Detailed information    

insolico Bioinformatically predicted

Overview

Name   brsR   Type   Regulator
Locus tag   R8613_RS01035 Genome accession   NZ_AP026919
Coordinates   182118..182558 (-) Length   146 a.a.
NCBI ID   WP_000861956.1    Uniprot ID   A0A0H2UNA2
Organism   Streptococcus pneumoniae strain PZ900700012     
Function   antagonizing the proteolysis of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 177118..187558
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8613_RS01000 (PC0012_01790) - 177520..177758 (+) 239 Protein_193 ABC transporter permease -
  R8613_RS01005 (PC0012_01800) - 177788..178357 (-) 570 WP_317648356.1 MptD family putative ECF transporter S component -
  R8613_RS01010 - 178495..178665 (+) 171 Protein_195 helix-turn-helix domain-containing protein -
  R8613_RS01015 (PC0012_01810) - 178717..179250 (+) 534 WP_000729029.1 hypothetical protein -
  R8613_RS01020 (PC0012_01820) nrdI 179328..179798 (+) 471 WP_000849621.1 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI -
  R8613_RS01025 (PC0012_01830) - 180091..181353 (-) 1263 WP_000075798.1 NRAMP family divalent metal transporter -
  R8613_RS01030 (PC0012_01840) - 181663..182121 (-) 459 WP_000745054.1 DUF3021 domain-containing protein -
  R8613_RS01035 (PC0012_01850) brsR 182118..182558 (-) 441 WP_000861956.1 LytTR family DNA-binding domain-containing protein Regulator
  R8613_RS01040 (PC0012_01860) hexB 182914..184863 (+) 1950 WP_317648357.1 DNA mismatch repair endonuclease MutL Machinery gene
  R8613_RS01045 (PC0012_01870) ribE 185188..185655 (-) 468 WP_001099502.1 6,7-dimethyl-8-ribityllumazine synthase -
  R8613_RS01050 (PC0012_01880) - 185656..186861 (-) 1206 WP_000456639.1 bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II -
  R8613_RS01055 (PC0012_01890) ribE 186881..187516 (-) 636 WP_000493842.1 riboflavin synthase -

Sequence

Protein


Download         Length: 146 a.a.        Molecular weight: 17183.84 Da        Isoelectric Point: 5.3783

>NTDB_id=81915 R8613_RS01035 WP_000861956.1 182118..182558(-) (brsR) [Streptococcus pneumoniae strain PZ900700012]
MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIKGKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSI
DLRLYQVLKLLPTNFIQISQSEIINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL

Nucleotide


Download         Length: 441 bp        

>NTDB_id=81915 R8613_RS01035 WP_000861956.1 182118..182558(-) (brsR) [Streptococcus pneumoniae strain PZ900700012]
ATGAAAGTAGAACTACAGATTAGTGAGACTTACGAGGAGGAAAAGCTGATTGTCCAAGCACCTCAAGAAACCGAAAAAGT
CCAGAAAGTCATCGAGTTCGCAGAAAATCTGGACCAAAGAGAAAAAATCAAAGGGAAAATCGATGATCAGGTCTATCTAG
TTGAGATTGGCAAGATTCAGCGCTTCTATATCGAGAATCGGAAGGTTCTAGCAGAAACCGCGAGTCAGACCTACAGCATT
GATTTGCGACTCTATCAGGTTCTTAAACTCTTGCCAACCAATTTTATCCAAATTTCCCAATCAGAAATCATCAATATCGA
TTCCATCTCTCACCTCAAGCTCACGCCAAACGGTCTGGTAGAAATTTTCTTGAAAAACGAAAGCTTCACCTACTCTTCAC
GCCGTTATCTAAAAACCATCAAGGAGAAATTAGAACTATGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(50-144)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UNA2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  brsR Streptococcus mutans UA159

36.054

100

0.363

Multiple sequence alignment