Detailed information    

insolico Bioinformatically predicted

Overview

Name   brsR   Type   Regulator
Locus tag   R4702_RS04270 Genome accession   NZ_CP137106
Coordinates   856595..857035 (+) Length   146 a.a.
NCBI ID   WP_000861968.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 16P4028     
Function   antagonizing the proteolysis of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 851595..862035
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4702_RS04245 ribE 851637..852272 (+) 636 WP_000493842.1 riboflavin synthase -
  R4702_RS04250 - 852292..853497 (+) 1206 WP_001820536.1 bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II -
  R4702_RS04255 ribE 853498..853965 (+) 468 WP_001099502.1 6,7-dimethyl-8-ribityllumazine synthase -
  R4702_RS04260 hexB 854290..856239 (-) 1950 WP_000018164.1 DNA mismatch repair endonuclease MutL Machinery gene
  R4702_RS04265 - 856382..856507 (+) 126 WP_001837110.1 hypothetical protein -
  R4702_RS04270 brsR 856595..857035 (+) 441 WP_000861968.1 LytTR family DNA-binding domain-containing protein Regulator
  R4702_RS04275 - 857032..857490 (+) 459 WP_000745059.1 DUF3021 domain-containing protein -
  R4702_RS04280 - 857800..859062 (+) 1263 WP_000075789.1 NRAMP family divalent metal transporter -
  R4702_RS04285 nrdI 859355..859825 (-) 471 WP_000849621.1 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI -
  R4702_RS04290 - 859903..860436 (-) 534 WP_000729034.1 hypothetical protein -
  R4702_RS04295 - 860497..861783 (-) 1287 WP_317810370.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 146 a.a.        Molecular weight: 17137.81 Da        Isoelectric Point: 5.9797

>NTDB_id=819138 R4702_RS04270 WP_000861968.1 856595..857035(+) (brsR) [Streptococcus pneumoniae strain 16P4028]
MKVELQISETYEEEKLIVQAPQPTDKVQKVIEFAENLDQREKIKGKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSI
DLRLYQVLKLLPTNFIQISQSEIINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL

Nucleotide


Download         Length: 441 bp        

>NTDB_id=819138 R4702_RS04270 WP_000861968.1 856595..857035(+) (brsR) [Streptococcus pneumoniae strain 16P4028]
ATGAAAGTAGAACTACAGATTAGTGAGACTTACGAGGAGGAAAAGCTGATTGTCCAAGCACCTCAGCCGACAGATAAAGT
CCAGAAAGTCATCGAGTTCGCAGAAAATCTGGACCAAAGAGAAAAAATCAAAGGGAAAATCGATGATCAGGTCTATCTAG
TTGAGATTGGCAAGATTCAGCGCTTCTATATCGAGAATCGGAAGGTTCTAGCAGAAACCGCGAGTCAGACCTACAGCATT
GATTTGCGACTCTATCAGGTTCTTAAACTCTTGCCAACCAATTTTATCCAAATTTCCCAATCAGAAATCATCAATATCGA
TTCCATCTCTCACCTCAAGCTCACGCCAAACGGTCTGGTAGAAATTTTCTTGAAAAACGAAAGCTTCACCTACTCTTCAC
GCCGTTATCTAAAAACCATCAAGGAGAAATTAGAACTATGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(50-144)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  brsR Streptococcus mutans UA159

36.054

100

0.363