Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   R4702_RS00510 Genome accession   NZ_CP137106
Coordinates   111552..112016 (-) Length   154 a.a.
NCBI ID   WP_001135768.1    Uniprot ID   A4L7L7
Organism   Streptococcus pneumoniae strain 16P4028     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 106552..117016
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4702_RS00490 - 107503..108471 (-) 969 WP_000105362.1 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha -
  R4702_RS00495 pdrM 108625..109986 (-) 1362 WP_050248721.1 sodium-coupled multidrug efflux MATE transporter PdrM -
  R4702_RS00500 - 109997..110257 (-) 261 WP_001105925.1 hypothetical protein -
  R4702_RS00505 - 110271..111539 (-) 1269 WP_050148311.1 dihydroorotase -
  R4702_RS00510 mutX 111552..112016 (-) 465 WP_001135768.1 8-oxo-dGTP diphosphatase Machinery gene
  R4702_RS00515 - 112026..112679 (-) 654 WP_001809694.1 uracil-DNA glycosylase -
  R4702_RS00520 - 112817..113464 (-) 648 WP_317810018.1 hypothetical protein -
  R4702_RS00525 - 113478..114191 (-) 714 WP_000499436.1 YjjG family noncanonical pyrimidine nucleotidase -
  R4702_RS00530 dhaM 114651..115031 (-) 381 WP_000443784.1 dihydroxyacetone kinase phosphoryl donor subunit DhaM -
  R4702_RS00535 - 115031..115105 (-) 75 Protein_107 dihydroxyacetone kinase subunit L -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 17812.16 Da        Isoelectric Point: 4.2287

>NTDB_id=819103 R4702_RS00510 WP_001135768.1 111552..112016(-) (mutX) [Streptococcus pneumoniae strain 16P4028]
MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGETPQECAAREILEETGLKAKPVLKGVITFPEFTPDLD
WYTYVFKVTEFEGDLIDCNEGTLEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE

Nucleotide


Download         Length: 465 bp        

>NTDB_id=819103 R4702_RS00510 WP_001135768.1 111552..112016(-) (mutX) [Streptococcus pneumoniae strain 16P4028]
ATGCCTCAGTTAGCGACGATTTGCTACATTGATAATGGGAAAGAACTGCTCATGCTCCATCGTAATAAGAAACCCAATGA
TGTCCATGAAGGGAAATGGATTGGTGTGGGTGGTAAGCTAGAGAGAGGAGAGACGCCCCAGGAATGCGCGGCGCGTGAAA
TCCTTGAAGAAACAGGGCTCAAAGCCAAGCCAGTTCTAAAAGGTGTCATCACTTTTCCTGAATTTACACCAGATTTAGAC
TGGTACACCTATGTTTTTAAGGTGACGGAGTTTGAGGGCGACTTGATTGACTGCAATGAGGGGACGCTAGAATGGGTTCC
CTATGATGAGGTTTTGAGCAAGCCGACTTGGGAAGGTGACCACACCTTTGTTGAGTGGCTTTTAGAGGATAAACCCTTCT
TTTCAGCCAAGTTTGTTTATGATGGGGATAAATTGTTGGATACCCAAGTTGATTTCTATGAATAA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A4L7L7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

98.701

100

0.987