Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   R4699_RS07665 Genome accession   NZ_CP137105
Coordinates   1532780..1534885 (-) Length   701 a.a.
NCBI ID   WP_050104862.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 16H2092     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1527780..1539885
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4699_RS07645 - 1528331..1528504 (-) 174 WP_001022228.1 S-ribosylhomocysteinase -
  R4699_RS07650 - 1528663..1530270 (-) 1608 WP_050105037.1 alpha-glucosidase -
  R4699_RS07655 - 1530423..1531907 (+) 1485 WP_050105038.1 DUF1846 domain-containing protein -
  R4699_RS07660 - 1532002..1532484 (+) 483 WP_000032550.1 S-ribosylhomocysteine lyase -
  R4699_RS07665 clpC 1532780..1534885 (-) 2106 WP_050104862.1 AAA family ATPase Regulator
  R4699_RS07670 mraY 1535476..1536456 (-) 981 WP_050104860.1 phospho-N-acetylmuramoyl-pentapeptide- transferase -
  R4699_RS07675 pbp2X 1536458..1538710 (-) 2253 WP_000872267.1 penicillin-binding protein 2X -
  R4699_RS07680 ftsL 1538714..1539031 (-) 318 WP_000818547.1 cell division protein FtsL -

Sequence

Protein


Download         Length: 701 a.a.        Molecular weight: 77530.25 Da        Isoelectric Point: 4.7315

>NTDB_id=819052 R4699_RS07665 WP_050104862.1 1532780..1534885(-) (clpC) [Streptococcus pneumoniae strain 16H2092]
MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEFAHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLG
RNLTAEAREGKLDPVIGRNKEIQETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKHKEIISIDISGL
EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKPALSRGELTVIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAENTFNILQGIRDLYQQHHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAA
QHPVTDVHAVEREIETEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTGIPVSQMGA
SDIERLKDMAHRLQGKVIGQDKAVEVVARAIRRNRAGFDEGNRPIGSFLFVGSTGVGKTELAKQLALDMFGTQDAIIRLD
MSEYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNT
VVIATSNAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLAEVNQTLAKKDIDLVVS
QAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLDAKHLEADMEDGVLVIREKA

Nucleotide


Download         Length: 2106 bp        

>NTDB_id=819052 R4699_RS07665 WP_050104862.1 1532780..1534885(-) (clpC) [Streptococcus pneumoniae strain 16H2092]
ATGAATAACAACTTTAATAATTTTAATAACATGGATGATTTATTTAACCAATTGATGGGTGGTATGCGAGGATACAGTTC
TGAAAATCGCCGTTACTTAATTAATGGACGCGAAGTCACACCTGAGGAATTTGCTCACTATCGTGCGACTGGTCAATTAC
CAGGAAATGCAGAAACTGATGTGCAAATGCCACAACAGGCATCAGGTATGAAACAAGACGGTGTCCTTGCAAAACTAGGT
CGAAACTTAACAGCAGAAGCGCGTGAGGGCAAGTTGGATCCTGTTATCGGACGAAACAAGGAAATTCAAGAAACATCTGA
AATCCTCTCACGCCGCACCAAGAACAATCCTGTTTTGGTCGGAGATGCAGGTGTTGGTAAGACAGCAGTTGTCGAAGGTC
TAGCGCAAGCCATTGTGAACGGAGATGTTCCTGCTGCTATCAAGCACAAGGAAATTATTTCTATTGATATCTCAGGTCTT
GAGGCTGGTACTCAATACCGTGGTAGCTTTGAAGAAAATGTCCAAAACTTAGTCAATGAAGTGAAAGAAGCAGGGAATAT
TATCCTCTTCTTTGATGAAATTCACCAAATTCTTGGTGCTGGTAGCACTGGTGGAGACAGTGGTTCTAAAGGACTTGCGG
ATATTCTCAAGCCAGCTCTCTCTCGTGGAGAATTGACAGTGATTGGGGCAACAACTCAAGACGAATACCGTAACACCATC
TTGAAGAATGCTGCTCTTGCTCGTCGTTTCAACGAAGTAAAGGTCAATGCTCCTTCAGCAGAGAATACTTTTAACATTCT
TCAAGGCATTCGTGATCTCTATCAACAACACCACAATGTCATCTTGCCAGACGAAGTCTTGAAAGCAGCGGTGGATTATT
CTGTTCAATACATTCCTCAACGTAGCTTGCCAGATAAGGCTATTGACCTTGTCGATGTAACGGCTGCTCACTTGGCGGCT
CAACATCCAGTAACAGATGTGCATGCTGTTGAACGAGAAATCGAAACGGAAAAAGACAAGCAAGAAAAAGCAGTTGAAGC
AGAAGATTTTGAAGCAGCTCTAAACTATAAAACACGCATTGCAGAATTGGAAAAGAAAATCGAAAACCACACAGAAGATA
TGAAAGTGACTGCAAGTGTCAACGATGTGGCTGAATCTGTGGAACGAATGACAGGTATCCCAGTATCGCAAATGGGAGCT
TCAGATATCGAACGTTTGAAAGATATGGCTCATCGCTTGCAAGGCAAGGTGATTGGTCAAGATAAGGCCGTAGAAGTTGT
AGCTCGTGCTATCCGTCGTAACCGTGCTGGTTTTGATGAAGGAAATCGCCCAATCGGCAGCTTCCTCTTTGTAGGGTCTA
CTGGGGTTGGTAAGACGGAGCTTGCTAAGCAATTGGCACTCGATATGTTTGGAACCCAGGATGCGATTATCCGTTTGGAT
ATGTCTGAATACAGTGACCGCACAGCTGTTTCTAAGCTAATTGGTACAACAGCAGGCTATGTGGGTTATGATGACAATAG
CAATACCTTAACAGAACGTGTTCGTCGCAATCCATACTCTATCATTCTCTTGGATGAAATTGAAAAGGCTGATCCTCAAG
TTATTACCCTTCTCCTCCAAGTTCTAGATGATGGTCGTTTGACAGATGGTCAAGGAAATACAGTAAACTTCAAGAATACT
GTCGTTATTGCGACCTCAAATGCTGGATTTGGCTATGAAGCCAATTTGACAGAAGATGCGGATAAACCAGAATTGATGGA
CCGTTTGAAACCCTTCTTCCGTCCAGAATTCCTCAACCGCTTTAATGCAGTCATCGAGTTCTCACACTTGACTAAGGAAG
ACCTTTCTAAGATTGTAGATTTGATGTTGGCTGAAGTTAACCAAACCTTGGCTAAGAAAGACATTGACTTGGTAGTCAGT
CAAGCGGCTAAAGATTATATCACAGAAGAAGGTTACGACGAAGTCATGGGGGTTCGTCCTCTCCGTCGAGTGGTTGAACA
AGAAATTCGTGATAAGGTGACAGACTTCCACTTGGATCATTTAGATGCTAAACATCTGGAAGCAGATATGGAAGATGGCG
TTTTGGTTATTCGTGAGAAAGCCTAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(610-680)

AAA domain (Cdc48 subfamily) (AAA_2)

(443-603)

AAA lid domain (AAA_lid_9)

(259-354)

ATPase family associated with various cellular activities (AAA) (AAA)

(118-250)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Lactococcus lactis subsp. cremoris KW2

49.766

91.441

0.455
  clpE Streptococcus mutans UA159

49.065

91.583

0.449
  clpE Streptococcus pneumoniae TIGR4

47.792

90.442

0.432
  clpE Streptococcus pneumoniae Rx1

47.792

90.442

0.432
  clpE Streptococcus pneumoniae D39

47.792

90.442

0.432
  clpE Streptococcus pneumoniae R6

47.792

90.442

0.432
  clpC Bacillus subtilis subsp. subtilis str. 168

44.684

92.582

0.414
  clpC Streptococcus pneumoniae Rx1

42.496

90.3

0.384
  clpC Streptococcus pneumoniae D39

42.496

90.3

0.384
  clpC Streptococcus pneumoniae TIGR4

42.338

90.3

0.382
  clpC Streptococcus thermophilus LMD-9

42.18

90.3

0.381
  clpC Streptococcus thermophilus LMG 18311

42.022

90.3

0.379
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

42.626

88.017

0.375
  clpC Streptococcus mutans UA159

41.748

88.16

0.368