Detailed information NTG0819041

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: QAO48_RS10170
• Genome accession: NZ_CP123119
• Coordinates: 2090024..2090911 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain GE-MSSA41
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2085024..2095911

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QAO48_RS10140 (QAO48_10115)	-	2085755..2086516 (+)	762	WP_000323451.1	alpha/beta hydrolase	-
QAO48_RS10145 (QAO48_10120)	-	2086762..2087217 (+)	456	WP_000106184.1	MarR family winged helix-turn-helix transcriptional regulator	-
QAO48_RS10150 (QAO48_10125)	-	2087339..2087440 (+)	102	WP_000731972.1	SE2200 family small protein	-
QAO48_RS10155 (QAO48_10130)	-	2087500..2088924 (-)	1425	WP_000953731.1	alkaline phosphatase	-
QAO48_RS10160 (QAO48_10135)	-	2089122..2089322 (+)	201	WP_000604723.1	hypothetical protein	-
QAO48_RS10165 (QAO48_10140)	braR	2089348..2090013 (+)	666	WP_000697883.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
QAO48_RS10170 (QAO48_10145)	braS	2090024..2090911 (+)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
QAO48_RS10175 (QAO48_10150)	-	2091019..2091774 (+)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
QAO48_RS10180 (QAO48_10155)	-	2091771..2093771 (+)	2001	WP_053014809.1	ABC transporter permease	-
QAO48_RS10185 (QAO48_10160)	-	2094435..2094548 (+)	114	WP_072384844.1	hypothetical protein	-
QAO48_RS10190 (QAO48_10165)	-	2094930..2095190 (+)	261	WP_072434822.1	hypothetical protein	-
QAO48_RS10195 (QAO48_10170)	-	2095200..2095697 (+)	498	WP_001065267.1	glutathione peroxidase	-
QAO48_RS10200 (QAO48_10175)	-	2095805..2095893 (-)	89	Protein_1972	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=819041 QAO48_RS10170 WP_000143420.1 2090024..2090911(+) (braS) [Staphylococcus aureus strain GE-MSSA41]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=819041 QAO48_RS10170 WP_000143420.1 2090024..2090911(+) (braS) [Staphylococcus aureus strain GE-MSSA41]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATATGTAAAAGATAATGGTATCGGTATTAGTGAGGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993