Detailed information NTG0818915

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: QAO38_RS10690
• Genome accession: NZ_CP123110
• Coordinates: 2177570..2178457 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain IT-MSSA47
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2172570..2183457

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QAO38_RS10660 (QAO38_10635)	-	2173301..2174062 (+)	762	WP_000323451.1	alpha/beta hydrolase	-
QAO38_RS10665 (QAO38_10640)	-	2174308..2174763 (+)	456	WP_000106184.1	MarR family winged helix-turn-helix transcriptional regulator	-
QAO38_RS10670 (QAO38_10645)	-	2174885..2174986 (+)	102	WP_000731972.1	SE2200 family small protein	-
QAO38_RS10675 (QAO38_10650)	-	2175046..2176470 (-)	1425	WP_000953731.1	alkaline phosphatase	-
QAO38_RS10680 (QAO38_10655)	-	2176668..2176868 (+)	201	WP_000604723.1	hypothetical protein	-
QAO38_RS10685 (QAO38_10660)	braR	2176894..2177559 (+)	666	WP_000697883.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
QAO38_RS10690 (QAO38_10665)	braS	2177570..2178457 (+)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
QAO38_RS10695 (QAO38_10670)	-	2178565..2179320 (+)	756	WP_001670202.1	ABC transporter ATP-binding protein	-
QAO38_RS10700 (QAO38_10675)	-	2179317..2181317 (+)	2001	WP_000776746.1	ABC transporter permease	-
QAO38_RS10705 (QAO38_10680)	-	2181981..2182094 (+)	114	WP_072384844.1	hypothetical protein	-
QAO38_RS10710 (QAO38_10685)	-	2182476..2182736 (+)	261	WP_072434822.1	hypothetical protein	-
QAO38_RS10715 (QAO38_10690)	-	2182746..2183243 (+)	498	WP_001065267.1	glutathione peroxidase	-
QAO38_RS10720 (QAO38_10695)	-	2183351..2183439 (-)	89	Protein_2078	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=818915 QAO38_RS10690 WP_000143420.1 2177570..2178457(+) (braS) [Staphylococcus aureus strain IT-MSSA47]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=818915 QAO38_RS10690 WP_000143420.1 2177570..2178457(+) (braS) [Staphylococcus aureus strain IT-MSSA47]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATATGTAAAAGATAATGGTATCGGTATTAGTGAGGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993