Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   R4708_RS03535 Genome accession   NZ_CP137104
Coordinates   737788..739893 (-) Length   701 a.a.
NCBI ID   WP_001063386.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain LM     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 732788..744893
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4708_RS03510 - 732825..733346 (+) 522 Protein_698 transposase -
  R4708_RS03515 - 733339..733506 (-) 168 WP_033607364.1 S-ribosylhomocysteinase -
  R4708_RS03520 - 733671..735278 (-) 1608 WP_001156827.1 alpha-glucosidase -
  R4708_RS03525 - 735431..736915 (+) 1485 WP_000743611.1 DUF1846 domain-containing protein -
  R4708_RS03530 - 737010..737492 (+) 483 WP_000032550.1 S-ribosylhomocysteine lyase -
  R4708_RS03535 clpC 737788..739893 (-) 2106 WP_001063386.1 AAA family ATPase Regulator
  R4708_RS03540 mraY 740502..741482 (-) 981 WP_000470817.1 phospho-N-acetylmuramoyl-pentapeptide- transferase -
  R4708_RS03545 pbp2X 741484..743736 (-) 2253 WP_000872242.1 penicillin-binding protein PBP2X -
  R4708_RS03550 ftsL 743740..744057 (-) 318 WP_000840840.1 cell division protein FtsL -

Sequence

Protein


Download         Length: 701 a.a.        Molecular weight: 77559.33 Da        Isoelectric Point: 4.7080

>NTDB_id=818894 R4708_RS03535 WP_001063386.1 737788..739893(-) (clpC) [Streptococcus pneumoniae strain LM]
MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEFAHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLG
RNLTAEAREGKLDPVIGRNKEIQETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKPALSRGELTVIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQHHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAA
QHPVTDVHAVEREIETEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTGIPVSQMGA
SDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLFVGSTGVGKTELAKQLALDMFGTQDAIIRLD
MSEYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNT
VIIATSNAGFGYEANLTEDADKPELMDRLKPFFRPELLNRFNAVIEFSHLTKEDLSKIVDLMLAEVNQTLAKKDIDLVVS
QAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLDAKHLEADMEDGVLVIREKV

Nucleotide


Download         Length: 2106 bp        

>NTDB_id=818894 R4708_RS03535 WP_001063386.1 737788..739893(-) (clpC) [Streptococcus pneumoniae strain LM]
ATGAATAACAACTTTAATAATTTTAATAACATGGATGATTTATTTAACCAATTGATGGGTGGTATGCGAGGATATAGTTC
TGAAAATCGCCGTTACTTAATTAATGGACGCGAAGTCACACCTGAGGAATTTGCTCACTATCGTGCGACTGGTCAATTAC
CAGGAAATGCAGAAACTGATGTGCAAATGCCACAACAGGCATCAGGTATGAAACAAGACGGTGTCCTTGCAAAACTAGGT
CGAAACTTGACAGCAGAAGCGCGTGAGGGCAAGTTGGATCCTGTTATCGGACGAAACAAGGAAATTCAAGAAACATCTGA
AATCCTCTCACGCCGCACCAAGAACAATCCTGTTTTGGTCGGAGATGCAGGTGTTGGTAAGACAGCAGTTGTCGAAGGTC
TAGCGCAAGCCATTGTGAACGGAGATGTTCCTGCTGCTATCAAGAACAAGGAAATTATTTCTATTGATATCTCAGGTCTT
GAGGCTGGTACTCAATACCGTGGTAGCTTTGAAGAAAATGTCCAAAACTTAGTCAATGAAGTGAAAGAAGCAGGGAATAT
TATCCTCTTCTTTGATGAAATTCACCAAATTCTTGGTGCTGGTAGCACTGGTGGAGACAGTGGTTCTAAAGGACTTGCGG
ATATTCTCAAGCCAGCTCTCTCTCGTGGAGAATTGACAGTGATTGGGGCAACAACTCAAGACGAATACCGTAACACCATC
TTGAAGAATGCTGCTCTTGCTCGTCGTTTCAACGAAGTGAAGGTCAATGCTCCTTCAGCAGAGAATACTTTTAAAATTCT
TCAAGGCATTCGTGACCTCTATCAACAACACCACAATGTCATCTTGCCAGACGAAGTCTTGAAAGCAGCGGTGGATTATT
CTGTTCAATACATTCCTCAACGTAGCTTGCCAGATAAGGCTATTGACCTTGTCGATGTAACGGCTGCTCACTTGGCGGCT
CAACATCCAGTAACAGATGTGCATGCTGTTGAACGAGAAATCGAAACGGAAAAAGACAAGCAAGAAAAAGCAGTTGAAGC
AGAAGATTTTGAAGCAGCTCTAAACTATAAAACACGCATTGCAGAATTGGAAAAGAAAATCGAAAACCACACAGAAGATA
TGAAAGTGACTGCAAGTGTCAACGATGTGGCTGAATCCGTGGAACGAATGACAGGTATCCCAGTATCGCAAATGGGAGCT
TCAGATATCGAACGTTTGAAAGATATGGCTCATCGCTTGCAAGACAAGGTGATTGGTCAAGATAAGGCCGTAGAAGCTGT
AGCTCGTGCTATCCGTCGTAACCGTGCTGGTTTTGATGAAGGAAATCGCCCAATCGGCAGCTTCCTCTTTGTAGGATCTA
CTGGGGTTGGTAAGACGGAGCTTGCTAAGCAATTGGCACTCGATATGTTTGGAACCCAGGATGCGATTATCCGTTTGGAT
ATGTCTGAATACAGTGACCGCACAGCTGTTTCTAAGCTAATTGGTACAACAGCAGGCTATGTGGGTTATGATGACAATAG
CAATACCTTAACAGAACGTGTTCGTCGCAATCCATACTCTATCATTCTCTTGGATGAAATTGAAAAGGCTGATCCTCAAG
TTATTACCCTTCTCCTCCAAGTTCTAGATGATGGTCGTTTGACAGATGGTCAAGGAAATACAGTAAACTTCAAGAACACT
GTCATTATTGCGACCTCAAATGCTGGATTTGGCTATGAAGCCAACTTGACAGAAGATGCGGATAAACCAGAATTGATGGA
CCGTTTGAAACCTTTCTTCCGTCCAGAACTCCTCAACCGCTTTAATGCAGTCATCGAGTTCTCACACTTGACTAAGGAAG
ACCTTTCTAAGATTGTAGATTTGATGTTGGCTGAAGTTAACCAAACCTTGGCTAAGAAAGACATTGACTTGGTAGTCAGT
CAAGCGGCTAAAGATTATATCACAGAAGAAGGTTACGACGAAGTCATGGGGGTTCGTCCTCTCCGTCGCGTGGTTGAACA
AGAAATTCGTGATAAGGTGACAGACTTCCACTTGGATCATTTAGATGCTAAACATCTGGAAGCAGATATGGAAGATGGCG
TTTTGGTTATTCGTGAGAAAGTCTAA

Domains

Predicted by InterProScan.

AAA lid domain (AAA_lid_9)

(259-354)

ATPase family associated with various cellular activities (AAA) (AAA)

(118-250)

AAA domain (Cdc48 subfamily) (AAA_2)

(443-603)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(610-680)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Lactococcus lactis subsp. cremoris KW2

49.922

91.441

0.456
  clpE Streptococcus mutans UA159

49.065

91.583

0.449
  clpE Streptococcus pneumoniae TIGR4

47.792

90.442

0.432
  clpE Streptococcus pneumoniae Rx1

47.792

90.442

0.432
  clpE Streptococcus pneumoniae D39

47.792

90.442

0.432
  clpE Streptococcus pneumoniae R6

47.792

90.442

0.432
  clpC Bacillus subtilis subsp. subtilis str. 168

44.737

92.154

0.412
  clpC Streptococcus pneumoniae Rx1

42.496

90.3

0.384
  clpC Streptococcus pneumoniae D39

42.496

90.3

0.384
  clpC Streptococcus pneumoniae TIGR4

42.338

90.3

0.382
  clpC Streptococcus thermophilus LMD-9

42.338

90.3

0.382
  clpC Streptococcus thermophilus LMG 18311

42.18

90.3

0.381
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

42.95

88.017

0.378
  clpC Streptococcus mutans UA159

41.748

88.16

0.368