Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   R4713_RS07500 Genome accession   NZ_CP137103
Coordinates   1402444..1404549 (+) Length   701 a.a.
NCBI ID   WP_001063396.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 21334     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1397444..1409549
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4713_RS07485 ftsL 1398325..1398642 (+) 318 WP_000840840.1 cell division protein FtsL -
  R4713_RS07490 pbp2X 1398646..1400898 (+) 2253 WP_279513995.1 penicillin-binding protein PBP2X -
  R4713_RS07495 mraY 1400900..1401880 (+) 981 WP_000470802.1 phospho-N-acetylmuramoyl-pentapeptide- transferase -
  R4713_RS07500 clpC 1402444..1404549 (+) 2106 WP_001063396.1 AAA family ATPase Regulator
  R4713_RS07505 - 1404844..1405326 (-) 483 WP_000032550.1 S-ribosylhomocysteine lyase -
  R4713_RS07510 - 1405421..1406905 (-) 1485 WP_000743620.1 DUF1846 domain-containing protein -
  R4713_RS07515 - 1407058..1408665 (+) 1608 WP_001156769.1 alpha-glucosidase -
  R4713_RS07520 - 1408830..1408997 (+) 168 WP_033604964.1 S-ribosylhomocysteinase -

Sequence

Protein


Download         Length: 701 a.a.        Molecular weight: 77647.45 Da        Isoelectric Point: 4.7591

>NTDB_id=818829 R4713_RS07500 WP_001063396.1 1402444..1404549(+) (clpC) [Streptococcus pneumoniae strain 21334]
MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEFAHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLG
RNLTAEAREGKLDPVIGRNKEIQETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKPALSRGELTVIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQHHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAA
QHPVTDVHAVEREIETEKDKQEKAVEAEDFEAALNYKTRIAELERKIENHTEDMKVTASVNDVAESVERMTGIPVSQMGA
SDIERLKDMAHRLQDKVIGQDKAVEVVARAIRRNRAGFDEGNRPIGNFLFVGSTGVGKTELAKQLALDMFGTQDAIIRLD
MSEYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNT
VIIATSNAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLAEVNQTLAKKDIDLVVS
QAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLDAKHLEADMKDGVLVIREKA

Nucleotide


Download         Length: 2106 bp        

>NTDB_id=818829 R4713_RS07500 WP_001063396.1 1402444..1404549(+) (clpC) [Streptococcus pneumoniae strain 21334]
ATGAATAACAACTTTAATAATTTTAATAACATGGATGATTTATTTAACCAATTGATGGGTGGTATGCGAGGATACAGTTC
TGAAAATCGCCGTTACTTAATTAATGGACGCGAAGTCACACCTGAGGAATTTGCTCACTATCGTGCGACTGGTCAATTAC
CAGGAAATGCAGAAACTGATGTGCAAATGCCACAACAGGCATCAGGTATGAAACAAGACGGTGTCCTTGCAAAACTAGGT
CGAAACTTAACAGCAGAAGCGCGTGAGGGCAAGTTGGACCCTGTTATCGGACGAAACAAGGAAATTCAAGAAACATCTGA
AATCCTCTCACGCCGCACCAAGAACAATCCTGTTTTGGTCGGAGATGCAGGTGTTGGTAAGACAGCAGTTGTCGAAGGTC
TAGCGCAAGCCATTGTGAACGGAGATGTTCCTGCTGCTATCAAGAACAAGGAAATTATTTCTATTGATATCTCAGGTCTT
GAGGCTGGTACTCAATACCGTGGTAGCTTTGAAGAAAATGTCCAAAACTTAGTCAATGAAGTGAAAGAAGCAGGGAATAT
TATCCTCTTCTTTGATGAAATTCACCAAATTCTTGGTGCTGGTAGCACTGGTGGAGACAGTGGTTCTAAAGGGCTTGCGG
ATATTCTCAAGCCAGCTCTCTCTCGTGGAGAATTGACAGTGATTGGGGCAACAACTCAAGACGAATACCGTAACACCATC
TTGAAGAATGCTGCTCTTGCTCGTCGTTTCAACGAAGTGAAGGTCAATGCTCCTTCGGCAGAGAATACTTTTAAAATTCT
TCAAGGAATTCGTGACCTCTATCAACAACACCACAATGTCATCTTGCCAGACGAAGTCTTGAAAGCAGCGGTGGATTATT
CTGTTCAATACATTCCTCAACGTAGCTTGCCAGATAAGGCTATTGACCTTGTCGATGTAACGGCTGCTCACTTGGCGGCT
CAACATCCAGTAACAGATGTGCATGCTGTTGAACGAGAAATCGAAACGGAAAAAGACAAGCAAGAAAAAGCAGTTGAAGC
AGAAGATTTTGAAGCAGCTCTAAACTATAAAACACGCATTGCAGAATTGGAAAGGAAAATCGAAAACCACACAGAAGATA
TGAAAGTGACTGCAAGTGTCAACGATGTGGCTGAATCTGTGGAACGAATGACAGGTATCCCAGTATCGCAAATGGGAGCT
TCAGATATCGAACGTTTGAAAGATATGGCTCATCGCTTGCAAGACAAGGTGATTGGTCAAGATAAGGCCGTAGAAGTTGT
AGCTCGTGCTATCCGTCGTAACCGTGCTGGTTTTGATGAAGGAAATCGCCCAATCGGCAACTTCCTCTTTGTAGGGTCTA
CTGGGGTTGGTAAGACGGAGCTTGCTAAGCAATTGGCACTCGATATGTTTGGAACCCAGGATGCGATTATCCGTTTGGAT
ATGTCTGAATACAGTGACCGCACAGCTGTTTCTAAGCTAATTGGTACAACAGCAGGCTATGTGGGTTATGATGACAATAG
CAATACCTTAACAGAACGTGTTCGTCGCAATCCATACTCTATCATTCTCTTGGATGAAATTGAAAAGGCTGACCCTCAAG
TTATTACCCTTCTCCTCCAAGTTCTAGATGATGGTCGTTTGACAGATGGTCAAGGAAATACAGTAAACTTCAAGAACACT
GTCATTATTGCGACCTCAAATGCTGGATTTGGCTATGAAGCCAACTTGACAGAAGATGCGGATAAACCAGAATTGATGGA
CCGTTTGAAACCCTTCTTCCGTCCAGAATTCCTCAACCGCTTTAATGCAGTCATCGAGTTCTCACACTTGACTAAGGAAG
ACCTTTCTAAGATTGTAGATTTGATGTTGGCTGAAGTTAACCAAACCTTGGCTAAGAAAGACATTGACTTGGTAGTCAGT
CAAGCGGCTAAAGATTATATCACAGAAGAAGGTTACGACGAAGTCATGGGGGTTCGTCCTCTCCGTCGCGTGGTTGAACA
AGAAATTCGTGATAAGGTGACAGACTTCCACTTGGATCATTTAGATGCTAAACATCTGGAAGCAGATATGAAAGATGGCG
TTTTGGTTATTCGTGAGAAAGCCTAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(610-680)

AAA lid domain (AAA_lid_9)

(259-354)

ATPase family associated with various cellular activities (AAA) (AAA)

(118-250)

AAA domain (Cdc48 subfamily) (AAA_2)

(443-603)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Lactococcus lactis subsp. cremoris KW2

49.922

91.441

0.456
  clpE Streptococcus mutans UA159

48.91

91.583

0.448
  clpE Streptococcus pneumoniae Rx1

47.627

90.157

0.429
  clpE Streptococcus pneumoniae D39

47.627

90.157

0.429
  clpE Streptococcus pneumoniae R6

47.627

90.157

0.429
  clpE Streptococcus pneumoniae TIGR4

47.551

90.3

0.429
  clpC Bacillus subtilis subsp. subtilis str. 168

43.639

96.434

0.421
  clpC Streptococcus pneumoniae Rx1

42.496

90.3

0.384
  clpC Streptococcus pneumoniae D39

42.496

90.3

0.384
  clpC Streptococcus pneumoniae TIGR4

42.338

90.3

0.382
  clpC Streptococcus thermophilus LMD-9

42.18

90.3

0.381
  clpC Streptococcus thermophilus LMG 18311

42.022

90.3

0.379
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

42.788

88.017

0.377
  clpC Streptococcus mutans UA159

41.748

88.16

0.368