Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   QAO20_RS11460 Genome accession   NZ_CP123106
Coordinates   2349215..2349931 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain IT-MSSA50     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2344215..2354931
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QAO20_RS11440 (QAO20_11410) - 2345308..2346258 (+) 951 WP_000790321.1 LacI family DNA-binding transcriptional regulator -
  QAO20_RS11445 (QAO20_11415) - 2346407..2347891 (+) 1485 WP_000141436.1 sucrose-6-phosphate hydrolase -
  QAO20_RS11450 (QAO20_11420) - 2347888..2348847 (+) 960 WP_001253299.1 carbohydrate kinase family protein -
  QAO20_RS11455 (QAO20_11425) - 2349036..2349143 (-) 108 WP_042900011.1 hypothetical protein -
  QAO20_RS11460 (QAO20_11430) agrA 2349215..2349931 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  QAO20_RS11465 (QAO20_11435) agrC 2349950..2351233 (-) 1284 WP_000447891.1 quorum-sensing sensor histidine kinase AgrC -
  QAO20_RS11470 (QAO20_11440) agrD 2351263..2351406 (-) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  QAO20_RS11475 (QAO20_11445) - 2351409..2351972 (-) 564 WP_001105700.1 accessory gene regulator AgrB -
  QAO20_RS11480 hld 2352262..2352342 (+) 81 WP_000046022.1 delta-hemolysin -
  QAO20_RS11485 (QAO20_11455) - 2352943..2353728 (-) 786 WP_000867957.1 carbon-nitrogen family hydrolase -
  QAO20_RS11490 (QAO20_11460) - 2353848..2354117 (+) 270 WP_000566932.1 hypothetical protein -
  QAO20_RS11495 (QAO20_11465) - 2354164..2354790 (-) 627 WP_000522379.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=818825 QAO20_RS11460 WP_000688492.1 2349215..2349931(-) (agrA) [Staphylococcus aureus strain IT-MSSA50]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=818825 QAO20_RS11460 WP_000688492.1 2349215..2349931(-) (agrA) [Staphylococcus aureus strain IT-MSSA50]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTAACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACACGTATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTAT
TGTCTAAAGATAATAGCGTCGAAACGATTGAGTTAAAACGTGGCAGTAATTCTGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACTAAGTCACACAGACTCATTGCGCATTTAGACAATCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGCTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATTG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1