Detailed information NTG0818746

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: QAY65_RS10015
• Genome accession: NZ_CP123102
• Coordinates: 2072839..2073726 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain IT-MSSA54
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2067839..2078726

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QAY65_RS09985 (QAY65_10025)	-	2068571..2069332 (+)	762	WP_000323441.1	alpha/beta hydrolase	-
QAY65_RS09990 (QAY65_10030)	-	2069577..2070032 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
QAY65_RS09995 (QAY65_10035)	-	2070154..2070255 (+)	102	WP_000731976.1	SE2200 family small protein	-
QAY65_RS10000 (QAY65_10040)	-	2070315..2071739 (-)	1425	WP_000953755.1	alkaline phosphatase	-
QAY65_RS10005 (QAY65_10045)	-	2071937..2072137 (+)	201	WP_000604730.1	hypothetical protein	-
QAY65_RS10010 (QAY65_10050)	braR	2072163..2072828 (+)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
QAY65_RS10015 (QAY65_10055)	braS	2072839..2073726 (+)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
QAY65_RS10020 (QAY65_10060)	-	2073834..2074589 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
QAY65_RS10025 (QAY65_10065)	-	2074586..2076586 (+)	2001	WP_000776751.1	ABC transporter permease	-
QAY65_RS10030 (QAY65_10070)	-	2077245..2077358 (+)	114	Protein_1937	hypothetical protein	-
QAY65_RS10035 (QAY65_10075)	-	2077740..2078000 (+)	261	WP_001791974.1	hypothetical protein	-
QAY65_RS10040 (QAY65_10080)	-	2078010..2078507 (+)	498	WP_001065268.1	glutathione peroxidase	-
QAY65_RS10045 (QAY65_10085)	-	2078615..2078707 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=818746 QAY65_RS10015 WP_000143425.1 2072839..2073726(+) (braS) [Staphylococcus aureus strain IT-MSSA54]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=818746 QAY65_RS10015 WP_000143425.1 2072839..2073726(+) (braS) [Staphylococcus aureus strain IT-MSSA54]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACATACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1