Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   QAY70_RS13475 Genome accession   NZ_CP123099
Coordinates   2727016..2727732 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain IT-MSSA55     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2722016..2732732
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QAY70_RS13455 (QAY70_13445) - 2723108..2724058 (+) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -
  QAY70_RS13460 (QAY70_13450) - 2724207..2725691 (+) 1485 WP_000141430.1 sucrose-6-phosphate hydrolase -
  QAY70_RS13465 (QAY70_13455) - 2725688..2726647 (+) 960 WP_001253305.1 carbohydrate kinase family protein -
  QAY70_RS13470 (QAY70_13460) - 2726835..2726944 (-) 110 Protein_2611 hypothetical protein -
  QAY70_RS13475 (QAY70_13465) agrA 2727016..2727732 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  QAY70_RS13480 (QAY70_13470) agrC 2727751..2729043 (-) 1293 WP_001789596.1 quorum-sensing sensor histidine kinase AgrC -
  QAY70_RS13485 (QAY70_13475) agrD 2729068..2729208 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  QAY70_RS13490 (QAY70_13480) agrB 2729205..2729774 (-) 570 WP_001105707.1 accessory gene regulator AgrB -
  QAY70_RS13495 (QAY70_13485) hld 2730064..2730144 (+) 81 WP_000046022.1 delta-hemolysin -
  QAY70_RS13500 (QAY70_13490) - 2730744..2731529 (-) 786 WP_000867942.1 carbon-nitrogen family hydrolase -
  QAY70_RS13505 (QAY70_13495) - 2731890..2732516 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=818708 QAY70_RS13475 WP_000688492.1 2727016..2727732(-) (agrA) [Staphylococcus aureus strain IT-MSSA55]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=818708 QAY70_RS13475 WP_000688492.1 2727016..2727732(-) (agrA) [Staphylococcus aureus strain IT-MSSA55]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGCGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1