Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   R4709_RS00540 Genome accession   NZ_CP137102
Coordinates   116503..116967 (-) Length   154 a.a.
NCBI ID   WP_001135768.1    Uniprot ID   A4L7L7
Organism   Streptococcus pneumoniae strain 16H3071-2     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 111503..121967
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4709_RS00520 - 112454..113422 (-) 969 WP_000105360.1 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha -
  R4709_RS00525 pdrM 113576..114937 (-) 1362 WP_000278537.1 sodium-coupled multidrug efflux MATE transporter PdrM -
  R4709_RS00530 - 114948..115208 (-) 261 WP_001105925.1 hypothetical protein -
  R4709_RS00535 - 115222..116490 (-) 1269 WP_000924492.1 dihydroorotase -
  R4709_RS00540 mutX 116503..116967 (-) 465 WP_001135768.1 8-oxo-dGTP diphosphatase Machinery gene
  R4709_RS00545 - 116977..117630 (-) 654 WP_001809694.1 uracil-DNA glycosylase -
  R4709_RS00550 - 117768..118415 (-) 648 WP_001824648.1 hypothetical protein -
  R4709_RS00555 - 118429..119142 (-) 714 WP_000499436.1 YjjG family noncanonical pyrimidine nucleotidase -
  R4709_RS00560 dhaM 119601..119981 (-) 381 WP_000443784.1 dihydroxyacetone kinase phosphoryl donor subunit DhaM -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 17812.16 Da        Isoelectric Point: 4.2287

>NTDB_id=818632 R4709_RS00540 WP_001135768.1 116503..116967(-) (mutX) [Streptococcus pneumoniae strain 16H3071-2]
MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGETPQECAAREILEETGLKAKPVLKGVITFPEFTPDLD
WYTYVFKVTEFEGDLIDCNEGTLEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE

Nucleotide


Download         Length: 465 bp        

>NTDB_id=818632 R4709_RS00540 WP_001135768.1 116503..116967(-) (mutX) [Streptococcus pneumoniae strain 16H3071-2]
ATGCCTCAGTTAGCGACGATTTGCTACATTGATAATGGGAAAGAACTGCTCATGCTCCATCGTAATAAGAAACCCAATGA
TGTCCATGAAGGGAAATGGATTGGTGTGGGTGGTAAGCTAGAGAGAGGAGAGACGCCCCAGGAATGCGCGGCGCGTGAAA
TCCTTGAAGAAACAGGGCTCAAAGCCAAGCCAGTTCTAAAAGGTGTCATCACTTTTCCTGAATTTACACCAGATTTAGAC
TGGTACACCTATGTTTTTAAGGTGACGGAGTTTGAGGGCGACTTGATTGACTGCAATGAGGGGACGCTAGAATGGGTTCC
CTATGACGAGGTTTTGAGCAAGCCGACTTGGGAAGGTGACCACACCTTTGTTGAGTGGCTTTTAGAGGATAAACCCTTCT
TTTCAGCTAAGTTTGTTTATGATGGGGATAAATTGTTGGATACCCAAGTTGATTTCTATGAATAA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A4L7L7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

98.701

100

0.987