Detailed information NTG0818619

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: QAO25_RS11985
• Genome accession: NZ_CP123095
• Coordinates: 2381730..2382617 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain MRSA-COL
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2376730..2387617

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QAO25_RS11955 (QAO25_11965)	-	2376749..2376841 (+)	93	WP_010956583.1	hypothetical protein	-
QAO25_RS11960 (QAO25_11970)	-	2376949..2377446 (-)	498	WP_001065268.1	glutathione peroxidase	-
QAO25_RS11965 (QAO25_11975)	-	2377456..2377716 (-)	261	WP_001789910.1	hypothetical protein	-
QAO25_RS11970 (QAO25_11980)	-	2378098..2378211 (-)	114	WP_011447078.1	hypothetical protein	-
QAO25_RS11975 (QAO25_11985)	-	2378870..2380870 (-)	2001	WP_000776751.1	ABC transporter permease	-
QAO25_RS11980 (QAO25_11990)	-	2380867..2381622 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
QAO25_RS11985 (QAO25_11995)	braS	2381730..2382617 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
QAO25_RS11990 (QAO25_12000)	braR	2382628..2383293 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
QAO25_RS11995 (QAO25_12005)	-	2383319..2383519 (-)	201	WP_000604728.1	hypothetical protein	-
QAO25_RS12000 (QAO25_12010)	-	2383717..2385141 (+)	1425	WP_000953744.1	alkaline phosphatase	-
QAO25_RS12005	-	2385201..2385302 (-)	102	WP_000731972.1	SE2200 family small protein	-
QAO25_RS12010 (QAO25_12020)	-	2385424..2385879 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
QAO25_RS12015 (QAO25_12025)	-	2386124..2386885 (-)	762	WP_000323455.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=818619 QAO25_RS11985 WP_000143419.1 2381730..2382617(-) (braS) [Staphylococcus aureus strain MRSA-COL]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=818619 QAO25_RS11985 WP_000143419.1 2381730..2382617(-) (braS) [Staphylococcus aureus strain MRSA-COL]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997