Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   QAO25_RS08830 Genome accession   NZ_CP123095
Coordinates   1760376..1761092 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain MRSA-COL     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1755376..1766092
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QAO25_RS08800 (QAO25_08800) - 1755595..1756221 (+) 627 WP_000522384.1 nitroreductase family protein -
  QAO25_RS08805 (QAO25_08805) - 1756582..1757367 (+) 786 WP_000867960.1 carbon-nitrogen family hydrolase -
  QAO25_RS08810 (QAO25_08810) hld 1757964..1758044 (-) 81 WP_000046022.1 delta-hemolysin -
  QAO25_RS08815 (QAO25_08815) agrB 1758334..1758903 (+) 570 WP_001105707.1 accessory gene regulator AgrB -
  QAO25_RS08820 (QAO25_08820) agrD 1758900..1759040 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  QAO25_RS08825 (QAO25_08825) agrC 1759065..1760357 (+) 1293 WP_010956571.1 quorum-sensing sensor histidine kinase AgrC -
  QAO25_RS08830 (QAO25_08830) agrA 1760376..1761092 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  QAO25_RS08835 (QAO25_08835) - 1761164..1761271 (+) 108 WP_001790167.1 hypothetical protein -
  QAO25_RS08840 (QAO25_08840) - 1761459..1762418 (-) 960 WP_001253312.1 carbohydrate kinase family protein -
  QAO25_RS08845 (QAO25_08845) - 1762415..1763899 (-) 1485 WP_000141406.1 sucrose-6-phosphate hydrolase -
  QAO25_RS08850 (QAO25_08850) - 1764048..1764998 (-) 951 WP_000790330.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=818615 QAO25_RS08830 WP_000688492.1 1760376..1761092(+) (agrA) [Staphylococcus aureus strain MRSA-COL]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=818615 QAO25_RS08830 WP_000688492.1 1760376..1761092(+) (agrA) [Staphylococcus aureus strain MRSA-COL]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1