Detailed information NTG0818526

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: QAY69_RS09520
• Genome accession: NZ_CP123091
• Coordinates: 1866772..1867659 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain MRSA-Mu50
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1861772..1872659

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QAY69_RS09490 (QAY69_09490)	-	1861791..1861883 (+)	93	WP_010956583.1	hypothetical protein	-
QAY69_RS09495 (QAY69_09495)	-	1861991..1862488 (-)	498	WP_001065268.1	glutathione peroxidase	-
QAY69_RS09500 (QAY69_09500)	-	1862498..1862758 (-)	261	WP_001791974.1	hypothetical protein	-
QAY69_RS09505 (QAY69_09505)	-	1863140..1863253 (-)	114	Protein_1842	hypothetical protein	-
QAY69_RS09510 (QAY69_09510)	-	1863912..1865912 (-)	2001	WP_000776751.1	ABC transporter permease	-
QAY69_RS09515 (QAY69_09515)	-	1865909..1866664 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
QAY69_RS09520 (QAY69_09520)	braS	1866772..1867659 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
QAY69_RS09525 (QAY69_09525)	braR	1867670..1868335 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
QAY69_RS09530 (QAY69_09530)	-	1868361..1868561 (-)	201	WP_000604730.1	hypothetical protein	-
QAY69_RS09535 (QAY69_09535)	-	1868759..1870183 (+)	1425	WP_000953755.1	alkaline phosphatase	-
QAY69_RS09540	-	1870243..1870344 (-)	102	WP_000731976.1	SE2200 family small protein	-
QAY69_RS09545 (QAY69_09545)	-	1870466..1870921 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
QAY69_RS09550 (QAY69_09550)	-	1871166..1871927 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=818526 QAY69_RS09520 WP_000143425.1 1866772..1867659(-) (braS) [Staphylococcus aureus strain MRSA-Mu50]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=818526 QAY69_RS09520 WP_000143425.1 1866772..1867659(-) (braS) [Staphylococcus aureus strain MRSA-Mu50]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1