Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   QAY69_RS06395 Genome accession   NZ_CP123091
Coordinates   1249176..1249892 (+) Length   238 a.a.
NCBI ID   WP_000688493.1    Uniprot ID   G9IE49
Organism   Staphylococcus aureus strain MRSA-Mu50     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1244176..1254892
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QAY69_RS06365 (QAY69_06370) - 1244393..1245019 (+) 627 WP_000522381.1 nitroreductase family protein -
  QAY69_RS06370 (QAY69_06375) - 1245380..1246165 (+) 786 WP_000867951.1 carbon-nitrogen family hydrolase -
  QAY69_RS06375 (QAY69_06380) hld 1246765..1246845 (-) 81 WP_000046022.1 delta-hemolysin -
  QAY69_RS06380 (QAY69_06385) - 1247135..1247698 (+) 564 WP_001105696.1 accessory gene regulator AgrB -
  QAY69_RS06385 (QAY69_06390) agrD 1247701..1247844 (+) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  QAY69_RS06390 (QAY69_06395) agrC 1247874..1249157 (+) 1284 WP_000447888.1 quorum-sensing sensor histidine kinase AgrC -
  QAY69_RS06395 (QAY69_06400) agrA 1249176..1249892 (+) 717 WP_000688493.1 quorum-sensing response regulator AgrA Regulator
  QAY69_RS06400 (QAY69_06405) - 1249967..1250076 (+) 110 Protein_1235 hypothetical protein -
  QAY69_RS06405 (QAY69_06410) - 1250264..1251223 (-) 960 WP_001253315.1 carbohydrate kinase family protein -
  QAY69_RS06410 (QAY69_06415) - 1251220..1252704 (-) 1485 WP_000141432.1 sucrose-6-phosphate hydrolase -
  QAY69_RS06415 (QAY69_06420) - 1252853..1253803 (-) 951 WP_000790331.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27920.92 Da        Isoelectric Point: 6.3009

>NTDB_id=818522 QAY69_RS06395 WP_000688493.1 1249176..1249892(+) (agrA) [Staphylococcus aureus strain MRSA-Mu50]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKK

Nucleotide


Download         Length: 717 bp        

>NTDB_id=818522 QAY69_RS06395 WP_000688493.1 1249176..1249892(+) (agrA) [Staphylococcus aureus strain MRSA-Mu50]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACAAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAAAATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-236)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G9IE49

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

99.58

0.996