Detailed information NTG0818311

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: QAY63_RS09260
• Genome accession: NZ_CP123080
• Coordinates: 1798485..1799372 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain SW-MRSA59
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1793485..1804372

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QAY63_RS09230 (QAY63_09240)	-	1793504..1793596 (+)	93	WP_010956583.1	hypothetical protein	-
QAY63_RS09235 (QAY63_09245)	-	1793704..1794201 (-)	498	WP_001065268.1	glutathione peroxidase	-
QAY63_RS09240 (QAY63_09250)	-	1794211..1794471 (-)	261	WP_001791974.1	hypothetical protein	-
QAY63_RS09245 (QAY63_09255)	-	1794853..1794966 (-)	114	Protein_1795	hypothetical protein	-
QAY63_RS09250 (QAY63_09260)	-	1795625..1797625 (-)	2001	WP_000776751.1	ABC transporter permease	-
QAY63_RS09255 (QAY63_09265)	-	1797622..1798377 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
QAY63_RS09260 (QAY63_09270)	braS	1798485..1799372 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
QAY63_RS09265 (QAY63_09275)	braR	1799383..1800048 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
QAY63_RS09270 (QAY63_09280)	-	1800074..1800274 (-)	201	WP_000604730.1	hypothetical protein	-
QAY63_RS09275 (QAY63_09285)	-	1800472..1801896 (+)	1425	WP_015445964.1	alkaline phosphatase	-
QAY63_RS09280	-	1801956..1802057 (-)	102	WP_000731976.1	SE2200 family small protein	-
QAY63_RS09285 (QAY63_09295)	-	1802179..1802634 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
QAY63_RS09290 (QAY63_09300)	-	1802879..1803640 (-)	762	WP_015445965.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=818311 QAY63_RS09260 WP_000143425.1 1798485..1799372(-) (braS) [Staphylococcus aureus strain SW-MRSA59]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=818311 QAY63_RS09260 WP_000143425.1 1798485..1799372(-) (braS) [Staphylococcus aureus strain SW-MRSA59]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1