Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   QAO35_RS05105 Genome accession   NZ_CP123074
Coordinates   1063913..1064629 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain SW-MRSA61     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1058913..1069629
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QAO35_RS05085 (QAO35_05100) - 1060005..1060955 (+) 951 WP_000790331.1 LacI family DNA-binding transcriptional regulator -
  QAO35_RS05090 (QAO35_05105) - 1061104..1062588 (+) 1485 WP_000141432.1 sucrose-6-phosphate hydrolase -
  QAO35_RS05095 (QAO35_05110) - 1062585..1063544 (+) 960 WP_001253312.1 carbohydrate kinase family protein -
  QAO35_RS05100 (QAO35_05115) - 1063732..1063841 (-) 110 Protein_993 hypothetical protein -
  QAO35_RS05105 (QAO35_05120) agrA 1063913..1064629 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  QAO35_RS05110 (QAO35_05125) agrC 1064648..1065931 (-) 1284 WP_015445896.1 quorum-sensing sensor histidine kinase AgrC -
  QAO35_RS05115 (QAO35_05130) agrD 1065961..1066104 (-) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  QAO35_RS05120 (QAO35_05135) - 1066107..1066670 (-) 564 WP_001105696.1 accessory gene regulator AgrB -
  QAO35_RS05125 (QAO35_05140) hld 1066960..1067040 (+) 81 WP_000046022.1 delta-hemolysin -
  QAO35_RS05130 (QAO35_05145) - 1067640..1068425 (-) 786 WP_000867951.1 carbon-nitrogen family hydrolase -
  QAO35_RS05135 (QAO35_05150) - 1068786..1069412 (-) 627 WP_000522381.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=818202 QAO35_RS05105 WP_000688492.1 1063913..1064629(-) (agrA) [Staphylococcus aureus strain SW-MRSA61]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=818202 QAO35_RS05105 WP_000688492.1 1063913..1064629(-) (agrA) [Staphylococcus aureus strain SW-MRSA61]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1