Detailed information NTG0818068

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: QAY81_RS00455
• Genome accession: NZ_CP123068
• Coordinates: 81737..82780 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain SW-MSSA65
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 76737..87780

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QAY81_RS00425 (QAY81_00425)	-	77044..77155 (+)	112	Protein_84	hypothetical protein	-
QAY81_RS00430 (QAY81_00430)	-	77184..77597 (+)	414	WP_001566709.1	hypothetical protein	-
QAY81_RS00435 (QAY81_00435)	-	78087..79073 (-)	987	WP_000999713.1	FUSC family protein	-
QAY81_RS00440 (QAY81_00440)	map	79663..80421 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
QAY81_RS00445 (QAY81_00445)	-	80638..81024 (+)	387	WP_001110179.1	hypothetical protein	-
QAY81_RS00450 (QAY81_00450)	liaF	81039..81740 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
QAY81_RS00455 (QAY81_00455)	vraS	81737..82780 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
QAY81_RS00460 (QAY81_00460)	vraR	82770..83399 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
QAY81_RS00465 (QAY81_00465)	-	83511..84728 (-)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
QAY81_RS00470 (QAY81_00470)	-	85006..85281 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
QAY81_RS00475 (QAY81_00475)	-	85288..85752 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
QAY81_RS00480 (QAY81_00480)	-	85899..86099 (+)	201	WP_000180460.1	DUF1128 family protein	-
QAY81_RS00485 (QAY81_00485)	-	86102..87358 (+)	1257	WP_001789555.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=818068 QAY81_RS00455 WP_001017131.1 81737..82780(+) (vraS) [Staphylococcus aureus strain SW-MSSA65]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=818068 QAY81_RS00455 WP_001017131.1 81737..82780(+) (vraS) [Staphylococcus aureus strain SW-MSSA65]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1