Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   LLUL033_RS11960 Genome accession   NZ_CP122980
Coordinates   2353301..2354332 (-) Length   343 a.a.
NCBI ID   WP_011836077.1    Uniprot ID   A0A084AC41
Organism   Lactococcus cremoris strain UL033     
Function   processing of CSP (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 2351273..2352448 2353301..2354332 flank 853


Gene organization within MGE regions


Location: 2351273..2354332
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLUL033_RS11945 (LLUL033_11945) - 2351273..2352448 (+) 1176 WP_003138385.1 IS256-like element IS905 family transposase -
  LLUL033_RS11950 (LLUL033_11950) - 2352483..2352800 (-) 318 WP_259687568.1 hypothetical protein -
  LLUL033_RS11955 (LLUL033_11955) - 2352868..2352981 (-) 114 WP_011836076.1 KxxxW-cyclized peptide pheromone -
  LLUL033_RS11960 (LLUL033_11960) sepM 2353301..2354332 (-) 1032 WP_011836077.1 SepM family pheromone-processing serine protease Regulator

Sequence

Protein


Download         Length: 343 a.a.        Molecular weight: 37403.02 Da        Isoelectric Point: 9.9119

>NTDB_id=817702 LLUL033_RS11960 WP_011836077.1 2353301..2354332(-) (sepM) [Lactococcus cremoris strain UL033]
MNKKNKKISPKLKWGISIGLIIVALLVLVYPTNYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYS
HFNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAVYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELSDTITA
VNGEEFKSSADMIAYVSKQKVGDSVTIEYTRIDGSKHKSTGKYIKISNGKTGIGIGLVDHTEVVTDPKVTVNAGSIGGPS
AGMMFTLEIYSQLTGKNLRGGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAK
KLKTKMKIVPVKTIQDALTYLEK

Nucleotide


Download         Length: 1032 bp        

>NTDB_id=817702 LLUL033_RS11960 WP_011836077.1 2353301..2354332(-) (sepM) [Lactococcus cremoris strain UL033]
ATGAACAAAAAAAATAAAAAAATCAGTCCCAAATTAAAATGGGGCATCTCTATTGGCCTGATTATTGTCGCTCTCCTTGT
TTTAGTGTATCCAACAAATTACTATGTGGAAATGCCTGGAACAACCGAGCCATTAGGGAAAATGGTCAAAGTTGAAGGAA
AAAAAGATGAGCACAAAGGTGACTTTTTCCTTACTACCGTTCAAATTGCGCGTGCTAATCTTGCCACAATGATTTACAGT
CATTTTAATAGTTTTACAAGCATTTACAGTGAACAAGAAATGACCGGTGGTCTTAATGATGCGCAGTTCAATCGTGTCAA
CCAGTTTTACATGGAAACTGCACAAAATACAGCCGTTTATCAGGCCTTCAAGTTGGCAAATAAACCCTATGAACTGAAAT
ATGAAGGGGTTTATGTCCTTGATATCGCTAAAAATTCGACTTTTAAAAATAAATTGGAACTTTCGGACACGATTACAGCA
GTCAATGGGGAAGAATTTAAATCAAGTGCAGATATGATTGCTTACGTTTCGAAGCAAAAAGTCGGCGATTCAGTTACCAT
TGAATATACACGGATTGATGGCAGTAAACACAAGTCTACTGGAAAATATATCAAAATCTCTAATGGAAAAACCGGAATCG
GAATTGGACTAGTTGACCATACTGAAGTAGTCACAGACCCAAAAGTTACAGTCAATGCAGGTTCAATCGGTGGACCATCT
GCCGGAATGATGTTTACACTAGAGATTTACAGTCAGTTGACAGGTAAAAATTTACGTGGTGGTCGCGAAATAGCAGGAAC
TGGAACGATTGAACATGATGGAAGCATTGGCCAAATCGGTGGGGTTGATAAAAAAGTAGCTACTGCTAGCAAAGAAGGCG
CAAAAGTTTTCTTAGTTCCTGACTCAGGCACCAAAAAAGAAAGCAGCAATAACTATCTTGGAGCCAAAGCAGCCGCTAAA
AAATTAAAAACGAAGATGAAAATTGTTCCCGTCAAGACTATTCAGGACGCTTTAACTTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(229-339)

PDZ domain (PDZ_2)

(135-193)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A084AC41

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

48.406

100

0.487