Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   QAD58_RS04550 Genome accession   NZ_CP122956
Coordinates   956582..958366 (+) Length   594 a.a.
NCBI ID   WP_286447978.1    Uniprot ID   -
Organism   Helicobacter pylori strain BT112     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 951582..963366
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QAD58_RS04520 (QAD58_04525) - 951883..952455 (-) 573 WP_101004270.1 Hpy99I family type II restriction endonuclease -
  QAD58_RS04525 (QAD58_04530) - 952449..953267 (-) 819 WP_000125518.1 DNA methyltransferase -
  QAD58_RS04530 (QAD58_04535) - 953631..955292 (+) 1662 WP_286447976.1 ABC transporter permease/substrate-binding protein -
  QAD58_RS04535 (QAD58_04540) - 955296..955937 (+) 642 WP_286447977.1 ATP-binding cassette domain-containing protein -
  QAD58_RS04540 (QAD58_04545) - 955949..956128 (-) 180 WP_000468796.1 hypothetical protein -
  QAD58_RS04545 (QAD58_04550) - 956120..956581 (+) 462 WP_000437191.1 hypothetical protein -
  QAD58_RS04550 (QAD58_04555) uvrC 956582..958366 (+) 1785 WP_286447978.1 excinuclease ABC subunit UvrC Machinery gene
  QAD58_RS04555 (QAD58_04560) - 958377..959642 (+) 1266 WP_286447979.1 homoserine dehydrogenase -
  QAD58_RS04560 (QAD58_04565) - 959643..959987 (+) 345 WP_001211660.1 YraN family protein -
  QAD58_RS04565 (QAD58_04570) trxA 960076..960396 (+) 321 WP_000020204.1 thioredoxin -
  QAD58_RS04570 (QAD58_04575) trxB 960402..961337 (+) 936 WP_286447980.1 thioredoxin-disulfide reductase -
  QAD58_RS04575 (QAD58_04580) - 961503..962324 (+) 822 WP_286447981.1 glycosyltransferase family 25 protein -
  QAD58_RS04580 (QAD58_04585) - 962522..962770 (-) 249 WP_000790557.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68852.02 Da        Isoelectric Point: 9.6142

>NTDB_id=817489 QAD58_RS04550 WP_286447978.1 956582..958366(+) (uvrC) [Helicobacter pylori strain BT112]
MADLLSSLKNLSHSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSVRNNEITPNYRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTNGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQVERCKAPCENKITKEEYLKIAKECLEMIENKDKLIKELELKMERLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYSGSNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQDFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFNQEKTSNEDLILEEARSLFQLECMPYRVEIFDT
SHHANSQCVGGMVVYENHEFQKNSYRHYHLKGSNEYTQMSELLTRRALDFNKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTPSDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=817489 QAD58_RS04550 WP_286447978.1 956582..958366(+) (uvrC) [Helicobacter pylori strain BT112]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTCATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCTGTCCGTAATAATGAAATCACGCCCA
ATTATCGCGCAAGCTTACGAATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAACAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAACCCAAATACAACATTCTTTTAAGAGATGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAACGGGGCTAAGGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAAGATAAAAAGGCATGCATGTTTTATCAAGTAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTGAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTCATTTATAGGGATAGGATTGCAAAAATCCAAAAAATC
GCCCCCTTTACTTGTATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATAGTGGGAGTAATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTCAACGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTAATGCCTGAACAGATTTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGATTTTATCTCTCACCAATACTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAACCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCGATCGCTCTTTCAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGACACC
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGAATTTCAAAAAAACTCCTATCGGCA
CTACCATTTAAAAGGCTCTAATGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGATTTTAATAAAGAGC
CACCGCCTAATTTGTGGGTGATCGATGGAGGAAGGGCACAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGTGCTAAAGACATTAT
CCATACGCCTAGCGATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCCAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCTGTTTTAAAAAAACGGATTTAA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrB/uvrC motif (UVR)

(205-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.633

100

0.966