Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   QAP05_RS03070 Genome accession   NZ_CP122952
Coordinates   624959..626743 (-) Length   594 a.a.
NCBI ID   WP_286493369.1    Uniprot ID   -
Organism   Helicobacter pylori strain BS27-1     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 619959..631743
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QAP05_RS03040 (QAP05_03040) - 620506..620754 (+) 249 WP_000790557.1 RNA-binding protein -
  QAP05_RS03045 (QAP05_03045) - 620959..621780 (-) 822 WP_286493299.1 glycosyltransferase family 25 protein -
  QAP05_RS03050 (QAP05_03050) trxB 621988..622923 (-) 936 WP_000564430.1 thioredoxin-disulfide reductase -
  QAP05_RS03055 (QAP05_03055) trxA 622929..623249 (-) 321 WP_000020204.1 thioredoxin -
  QAP05_RS03060 (QAP05_03060) - 623338..623682 (-) 345 WP_140567389.1 YraN family protein -
  QAP05_RS03065 (QAP05_03065) - 623683..624948 (-) 1266 WP_286493355.1 homoserine dehydrogenase -
  QAP05_RS03070 (QAP05_03070) uvrC 624959..626743 (-) 1785 WP_286493369.1 excinuclease ABC subunit UvrC Machinery gene
  QAP05_RS03075 (QAP05_03075) - 626744..627205 (-) 462 WP_286493380.1 hypothetical protein -
  QAP05_RS03080 (QAP05_03080) - 627197..627376 (+) 180 WP_031249628.1 hypothetical protein -
  QAP05_RS03085 (QAP05_03085) - 627379..628029 (-) 651 WP_286493417.1 ABC transporter ATP-binding protein -
  QAP05_RS03090 (QAP05_03090) - 628026..629588 (-) 1563 WP_286493424.1 ABC transporter permease/substrate-binding protein -
  QAP05_RS03095 (QAP05_03095) - 629689..630135 (-) 447 WP_187845673.1 hypothetical protein -
  QAP05_RS03100 (QAP05_03100) motB 630132..630905 (-) 774 WP_286493453.1 flagellar motor protein MotB -
  QAP05_RS03105 (QAP05_03105) motA 630908..631681 (-) 774 WP_000366185.1 flagellar motor stator protein MotA -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68681.89 Da        Isoelectric Point: 9.5666

>NTDB_id=817397 QAP05_RS03070 WP_286493369.1 624959..626743(-) (uvrC) [Helicobacter pylori strain BS27-1]
MADLLSSLKNLSNSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSVRNNEITPNYRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDKLIKELELKMERLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGGSNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAVINHYQLHLPLMPEQILLN
ACSNETLKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEVRSLFELECMPYRVEIFDT
SHHANSQCVGGMVVYENNAFQKDAYRRYHLKGSDEYTQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTPSDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASDQEKNAVLKKRN

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=817397 QAP05_RS03070 WP_286493369.1 624959..626743(-) (uvrC) [Helicobacter pylori strain BS27-1]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTAACAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
GCTCTATATCGGTAAGGCGAAAAATTTAAAAAAACGCATCAAAAGCTATTTTTCTGTCCGTAATAATGAAATCACGCCCA
ATTATCGCGCTAGCTTACGCATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCCTATATTTACATGGATTTTTCCACCGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGTGGGGCTAAGGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTGGTTCAAAAGAAA
AATTGCATCAAAGATAAAAAGGCGTGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTGAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTCATTTACAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTGGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATGGCGGGAGTAATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTCAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCGTTATCAATCATTACCAATTGCATTTGCCTTTGATGCCAGAACAGATTTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGAATTTATCTCTCATCAATACTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGTCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGTGCGATCGCTCTTTGAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAACAATGCATTCCAAAAAGACGCTTATCGGCG
CTACCATTTAAAAGGCTCTGATGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGATTTTGCCAAAGAGC
CACCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGTTCTAAAGGGGGCGCTAAAGACATTAT
CCATACGCCTAGCGATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCACAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGCATA
GGAGAAGCCAGCGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCAAGCGATCAGGAAAAAAA
CGCCGTTTTGAAAAAACGAAATTAA

Domains

Predicted by InterproScan.

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

UvrB/uvrC motif (UVR)

(205-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

97.47

99.832

0.973