Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   QAP01_RS03375 Genome accession   NZ_CP122950
Coordinates   701271..703055 (-) Length   594 a.a.
NCBI ID   WP_286498683.1    Uniprot ID   -
Organism   Helicobacter pylori strain BS28-1     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 696271..708055
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QAP01_RS03345 (QAP01_03345) - 696805..697053 (+) 249 WP_000790557.1 RNA-binding protein -
  QAP01_RS03350 (QAP01_03350) - 697268..698092 (-) 825 WP_286498680.1 glycosyltransferase family 25 protein -
  QAP01_RS03355 (QAP01_03355) trxB 698300..699235 (-) 936 WP_286498681.1 thioredoxin-disulfide reductase -
  QAP01_RS03360 (QAP01_03360) trxA 699241..699561 (-) 321 WP_000020204.1 thioredoxin -
  QAP01_RS03365 (QAP01_03365) - 699650..699994 (-) 345 WP_001211718.1 YraN family protein -
  QAP01_RS03370 (QAP01_03370) - 699995..701260 (-) 1266 WP_286498682.1 homoserine dehydrogenase -
  QAP01_RS03375 (QAP01_03375) uvrC 701271..703055 (-) 1785 WP_286498683.1 excinuclease ABC subunit UvrC Machinery gene
  QAP01_RS03380 (QAP01_03380) - 703056..703517 (-) 462 WP_286498684.1 hypothetical protein -
  QAP01_RS03385 (QAP01_03385) - 703509..703688 (+) 180 WP_000468794.1 hypothetical protein -
  QAP01_RS03390 (QAP01_03390) - 703700..704341 (-) 642 WP_286498685.1 ATP-binding cassette domain-containing protein -
  QAP01_RS03395 (QAP01_03395) - 704345..706006 (-) 1662 WP_286498765.1 ABC transporter permease/substrate-binding protein -
  QAP01_RS03400 (QAP01_03400) - 706066..706503 (-) 438 WP_001879940.1 hypothetical protein -
  QAP01_RS03405 (QAP01_03405) motB 706509..707282 (-) 774 WP_121104643.1 flagellar motor protein MotB -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68695.00 Da        Isoelectric Point: 9.7467

>NTDB_id=817355 QAP01_RS03375 WP_286498683.1 701271..703055(-) (uvrC) [Helicobacter pylori strain BS28-1]
MADLLSSLKNLSNSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIRNNEITPNHRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDKLIKELELKMERLSNNLRFEEALIYRDRIEKIQKI
APFTCMDLAKLYDLDIFAFYGASNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLIPEQILLN
ACSNEVLKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFKLECMPYRVEIFDT
SHHANSQCVGGMVVYENNAFQKNSYRRYHLKGSNEYTQMSELLTRRALDFTKEPPPNLWVIDGGKAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTPSNTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASDQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=817355 QAP01_RS03375 WP_286498683.1 701271..703055(-) (uvrC) [Helicobacter pylori strain BS28-1]
ATGGCTGATTTATTGTCTAGTTTGAAAAACCTTTCTAACAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
GCTCTATATCGGTAAGGCGAAAAATTTAAAAAAACGCATCAAAAGCTATTTTTCCATCCGTAATAATGAAATCACGCCCA
ATCATCGCGCAAGCTTGCGCATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTATATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAGGATATTTTGGACAGCTTGTATGAATTGCTCCCATTAGTTCAAAAGAAA
AATTGCATCAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACTAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTAATTTACAGGGACAGGATTGAAAAAATCCAAAAAATC
GCCCCCTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATGGCGCAAGCAATAAGGCGGT
CTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTCAACGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTAATACCAGAACAGATTTTATTGAAC
GCTTGCTCTAACGAAGTGCTTAAGGAATTGCAAGAATTTATCTCCCATCAATATTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAAGGCGACAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCGATCGCTCTTCAAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATAACGCATTCCAAAAAAACTCTTATCGGCG
CTACCATTTAAAAGGCTCTAACGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGATTTTACTAAAGAGC
CGCCGCCTAATTTGTGGGTGATCGATGGAGGGAAGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGAGGCGCTAAAGACATTAT
CCATACGCCTAGCAATACTTTTAAATTGCTCCCTAGTGACAAACGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGCATA
GGAGAAGCCAGCGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGATCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATTTAA

Domains

Predicted by InterproScan.

UvrB/uvrC motif (UVR)

(205-239)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

97.811

100

0.978