Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   QAP00_RS03335 Genome accession   NZ_CP122949
Coordinates   687483..689267 (-) Length   594 a.a.
NCBI ID   WP_309256937.1    Uniprot ID   -
Organism   Helicobacter pylori strain BS22     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 682483..694267
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QAP00_RS03305 (QAP00_03310) - 683068..683316 (+) 249 WP_000790557.1 RNA-binding protein -
  QAP00_RS03310 (QAP00_03315) - 683523..684344 (-) 822 WP_309256933.1 glycosyltransferase family 25 protein -
  QAP00_RS03315 (QAP00_03320) trxB 684512..685447 (-) 936 WP_024773194.1 thioredoxin-disulfide reductase -
  QAP00_RS03320 (QAP00_03325) trxA 685453..685773 (-) 321 WP_000020200.1 thioredoxin -
  QAP00_RS03325 (QAP00_03330) - 685862..686206 (-) 345 WP_001211669.1 YraN family protein -
  QAP00_RS03330 (QAP00_03335) - 686207..687472 (-) 1266 WP_309256936.1 homoserine dehydrogenase -
  QAP00_RS03335 (QAP00_03340) uvrC 687483..689267 (-) 1785 WP_309256937.1 excinuclease ABC subunit UvrC Machinery gene
  QAP00_RS03340 (QAP00_03345) - 689268..689729 (-) 462 WP_101025272.1 hypothetical protein -
  QAP00_RS03345 (QAP00_03350) - 689721..689900 (+) 180 WP_309256938.1 hypothetical protein -
  QAP00_RS03350 (QAP00_03355) - 689903..690553 (-) 651 WP_309256939.1 ABC transporter ATP-binding protein -
  QAP00_RS03355 (QAP00_03360) - 690557..692218 (-) 1662 WP_309256940.1 ABC transporter permease/substrate-binding protein -
  QAP00_RS03360 (QAP00_03365) - 692399..692836 (-) 438 WP_001031792.1 hypothetical protein -
  QAP00_RS03365 (QAP00_03370) motB 692840..693607 (-) 768 WP_140608582.1 flagellar motor protein MotB -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68731.97 Da        Isoelectric Point: 9.6287

>NTDB_id=817338 QAP00_RS03335 WP_309256937.1 687483..689267(-) (uvrC) [Helicobacter pylori strain BS22]
MADLLSSLKNLSSSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIRNNEITPNHRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDRLIKELELKMERLSNNLRFEEALIYRDRITKIQKI
APFTCMDLAKLYDLDIFAFYGGSNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAVINHYQSHLPLMPEQILLN
ACSNETLKELQDFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEVRSLFKLECMPYRVEIFDT
SHHANSQCVGGMVVYENHEFQKNSYRCYHLKGSNEYTQMSELLTRRALDFNKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTASDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=817338 QAP00_RS03335 WP_309256937.1 687483..689267(-) (uvrC) [Helicobacter pylori strain BS22]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTAGTAGTAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAAGCGAAAAACTTAAAAAAGCGCATCAAAAGCTATTTTTCCATCCGTAATAATGAAATCACGCCCA
ACCATCGCGCAAGCTTACGCATCCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTGGAAAATTCTTTAATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACCGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTCACGAGCGGGGCTAAAGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAGACTCATCAAAGAACTTGAATTAA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTCATTTATAGGGACAGGATTACAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTGGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATGGCGGGAGTAATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTCAACGGATTTGACA
CTGATGAAGCGATGAAACAAGCCGTTATCAATCATTACCAATCGCATTTGCCTTTAATGCCAGAACAGATTTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGATTTTATCTCTCACCAATACTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAAGGCGATAAGCTTGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGTGCGATCGCTCTTTAAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGATACA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGAATTTCAAAAAAACTCCTATCGGTG
CTACCATTTAAAAGGCTCTAATGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGATTTTAATAAAGAGC
CACCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGTGCTAAAGACATCAT
CCACACCGCTAGCGATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAATGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCACAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCCAGCGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCTGTTTTAAAAAAACGAATTTAA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

UvrB/uvrC motif (UVR)

(205-239)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

97.306

100

0.973