Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   QAP02_RS03290 Genome accession   NZ_CP122948
Coordinates   677594..679378 (-) Length   594 a.a.
NCBI ID   WP_286464701.1    Uniprot ID   -
Organism   Helicobacter pylori strain BS21     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 672594..684378
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QAP02_RS07735 - 672774..672968 (-) 195 Protein_624 hypothetical protein -
  QAP02_RS03260 (QAP02_03260) - 673119..673367 (+) 249 WP_000790557.1 RNA-binding protein -
  QAP02_RS03265 (QAP02_03265) - 673588..674409 (-) 822 WP_286464699.1 glycosyltransferase family 25 protein -
  QAP02_RS03270 (QAP02_03270) trxB 674624..675559 (-) 936 WP_120926753.1 thioredoxin-disulfide reductase -
  QAP02_RS03275 (QAP02_03275) trxA 675565..675885 (-) 321 WP_000020189.1 thioredoxin -
  QAP02_RS03280 (QAP02_03280) - 675974..676318 (-) 345 WP_001211718.1 YraN family protein -
  QAP02_RS03285 (QAP02_03285) - 676318..677583 (-) 1266 WP_286464700.1 homoserine dehydrogenase -
  QAP02_RS03290 (QAP02_03290) uvrC 677594..679378 (-) 1785 WP_286464701.1 excinuclease ABC subunit UvrC Machinery gene
  QAP02_RS03295 (QAP02_03295) - 679379..679840 (-) 462 WP_000437191.1 hypothetical protein -
  QAP02_RS03300 (QAP02_03300) - 679832..680011 (+) 180 WP_000468796.1 hypothetical protein -
  QAP02_RS03305 (QAP02_03305) - 680023..680664 (-) 642 WP_286464702.1 ATP-binding cassette domain-containing protein -
  QAP02_RS03310 (QAP02_03310) - 680668..682329 (-) 1662 WP_286464703.1 ABC transporter permease/substrate-binding protein -
  QAP02_RS03315 (QAP02_03315) - 682398..682835 (-) 438 WP_014536745.1 hypothetical protein -
  QAP02_RS03320 (QAP02_03320) motB 682841..683614 (-) 774 WP_286464704.1 flagellar motor protein MotB -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68816.04 Da        Isoelectric Point: 9.6314

>NTDB_id=817314 QAP02_RS03290 WP_286464701.1 677594..679378(-) (uvrC) [Helicobacter pylori strain BS21]
MADLLSSLKNLSHSSGVYQYFDKNRQLLYIGKAKNLNKRIRSYFSIHNNEITPNHRTSLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDRLIKELELKMERLSNNLRFEEALIYRDRITKIQKI
APFTCMDLAKLYDLDIFAFYGGSNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAVINHYQSHLPLMPEQILLS
ACSNEVLKELQDFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEVRSLFKLECMPYRVEIFDT
SHHANSQCVGGMVVYENHEFQKNSYRRYHLKGSNEYTQMSELLTRRALDFAKEPPPNLWVIDGGRVQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTASDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=817314 QAP02_RS03290 WP_286464701.1 677594..679378(-) (uvrC) [Helicobacter pylori strain BS21]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTCATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAACAAGCGTATCAGAAGTTATTTTTCTATCCACAATAATGAAATCACGCCCA
ATCATCGCACCAGCTTACGCATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCCTATATTTACATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGTCCTTTTACGAGCGGGGCTAAGGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAAGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAGACTCATCAAAGAACTTGAATTAA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTCATTTATAGGGACAGGATTACAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTGGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATGGCGGGAGTAATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTCAACGGATTTGACA
CTGATGAAGCGATGAAACAAGCCGTTATCAATCATTACCAATCGCATTTGCCTTTGATGCCTGAACAGATCTTATTGAGC
GCTTGCTCTAATGAAGTGCTTAAAGAATTGCAAGATTTTATCTCTCACCAATACTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGTGCGATCGCTCTTTAAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGATACA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGAATTTCAAAAAAACTCCTATCGGCG
CTACCATTTAAAAGGCTCTAACGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGATTTTGCCAAAGAGC
CGCCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGTGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGTGCTAAAGACATCAT
CCATACCGCTAGCGATACTTTTAAATTGCTCCCTAGCGACAAGCGCTTGCAGTGGGTTCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGCATA
GGAGAAGCCAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATATAA

Domains

Predicted by InterproScan.

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrB/uvrC motif (UVR)

(205-239)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.465

100

0.965