Detailed information
Bioinformatically predicted
Overview
| Name | comB3 | Type | Machinery gene |
| Locus tag | QAD57_RS00160 | Genome accession | NZ_CP122947 |
| Coordinates | 45345..45608 (-) | Length | 87 a.a. |
| NCBI ID | WP_001177713.1 | Uniprot ID | - |
| Organism | Helicobacter pylori strain BS07 | ||
| Function | transformation-associated type IV transport system (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1303..111685 | 45345..45608 | within | 0 |
Gene organization within MGE regions
Location: 1303..111685
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QAD57_RS00010 (QAD57_00010) | - | 1650..2384 (+) | 735 | WP_286445820.1 | Fic family protein | - |
| QAD57_RS00015 (QAD57_00015) | - | 3408..5441 (+) | 2034 | WP_286445821.1 | relaxase/mobilization nuclease domain-containing protein | - |
| QAD57_RS00020 (QAD57_00020) | - | 6526..7597 (+) | 1072 | Protein_3 | tyrosine-type recombinase/integrase | - |
| QAD57_RS00025 (QAD57_00025) | ctkA | 7912..8889 (-) | 978 | WP_015642201.1 | serine/threonine-protein kinase CtkA | - |
| QAD57_RS00030 (QAD57_00030) | - | 9118..9846 (+) | 729 | WP_000620284.1 | hypothetical protein | - |
| QAD57_RS00035 (QAD57_00035) | - | 9868..11124 (-) | 1257 | WP_286445822.1 | hypothetical protein | - |
| QAD57_RS00040 (QAD57_00040) | - | 11121..12371 (-) | 1251 | WP_286445823.1 | P-type conjugative transfer protein TrbL | - |
| QAD57_RS00045 (QAD57_00045) | - | 12368..13801 (-) | 1434 | WP_286445824.1 | hypothetical protein | - |
| QAD57_RS00050 (QAD57_00050) | - | 13811..15814 (-) | 2004 | Protein_9 | hypothetical protein | - |
| QAD57_RS00055 (QAD57_00055) | - | 15814..16881 (-) | 1068 | WP_286445825.1 | ArdC family protein | - |
| QAD57_RS00060 (QAD57_00060) | - | 16882..17046 (-) | 165 | WP_286445826.1 | hypothetical protein | - |
| QAD57_RS00065 (QAD57_00065) | - | 17670..18317 (+) | 648 | WP_286445827.1 | ParA family protein | - |
| QAD57_RS00070 (QAD57_00070) | - | 18379..18756 (+) | 378 | WP_021308000.1 | hypothetical protein | - |
| QAD57_RS00075 (QAD57_00075) | - | 18734..19306 (+) | 573 | WP_286445828.1 | hypothetical protein | - |
| QAD57_RS00080 (QAD57_00080) | - | 19428..20231 (-) | 804 | WP_286445829.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | - |
| QAD57_RS00085 (QAD57_00085) | - | 20203..20454 (-) | 252 | WP_000006537.1 | hypothetical protein | - |
| QAD57_RS00090 (QAD57_00090) | - | 20505..22568 (-) | 2064 | WP_286445830.1 | type IA DNA topoisomerase | - |
| QAD57_RS00095 (QAD57_00095) | - | 22657..28512 (-) | 5856 | Protein_18 | SNF2-related protein | - |
| QAD57_RS07715 | - | 29091..29888 (-) | 798 | WP_350310569.1 | helicase | - |
| QAD57_RS00100 (QAD57_00100) | - | 31313..33577 (-) | 2265 | WP_286445831.1 | type IV secretory system conjugative DNA transfer family protein | - |
| QAD57_RS00105 (QAD57_00105) | - | 33574..34092 (-) | 519 | WP_286445832.1 | replication regulatory RepB family protein | - |
| QAD57_RS00110 (QAD57_00110) | - | 34089..35031 (-) | 943 | Protein_22 | CpaF/VirB11 family protein | - |
| QAD57_RS00115 (QAD57_00115) | - | 35051..35308 (-) | 258 | WP_286445833.1 | hypothetical protein | - |
| QAD57_RS00120 (QAD57_00120) | - | 35326..36303 (-) | 978 | WP_286445834.1 | hypothetical protein | - |
| QAD57_RS00125 (QAD57_00125) | - | 36316..38368 (-) | 2053 | Protein_25 | collagen-like protein | - |
| QAD57_RS00130 (QAD57_00130) | comB10 | 38352..39554 (-) | 1203 | WP_140528722.1 | DNA type IV secretion system protein ComB10 | Machinery gene |
| QAD57_RS00135 (QAD57_00135) | - | 39551..41227 (-) | 1677 | Protein_27 | TrbG/VirB9 family P-type conjugative transfer protein | - |
| QAD57_RS00140 (QAD57_00140) | - | 41224..42393 (-) | 1170 | WP_286445836.1 | VirB8/TrbF family protein | - |
| QAD57_RS00145 (QAD57_00145) | - | 42386..42520 (-) | 135 | WP_000738749.1 | hypothetical protein | - |
| QAD57_RS00150 (QAD57_00150) | - | 42540..45098 (-) | 2559 | WP_286445837.1 | VirB4 family type IV secretion/conjugal transfer ATPase | - |
| QAD57_RS00155 (QAD57_00155) | - | 45098..45334 (-) | 237 | WP_180521129.1 | hypothetical protein | - |
| QAD57_RS00160 (QAD57_00160) | comB3 | 45345..45608 (-) | 264 | WP_001177713.1 | hypothetical protein | Machinery gene |
| QAD57_RS00165 (QAD57_00165) | comB2 | 45619..45903 (-) | 285 | WP_286445838.1 | TrbC/VirB2 family protein | Machinery gene |
| QAD57_RS00170 (QAD57_00170) | - | 45900..46379 (-) | 480 | WP_180598625.1 | hypothetical protein | - |
| QAD57_RS00175 (QAD57_00175) | - | 46483..47271 (-) | 789 | WP_120945486.1 | integrase | - |
| QAD57_RS00180 (QAD57_00180) | - | 47319..47978 (-) | 660 | WP_286445839.1 | DEAD/DEAH box helicase family protein | - |
| QAD57_RS00185 (QAD57_00185) | - | 48034..48168 (+) | 135 | WP_001146209.1 | hypothetical protein | - |
| QAD57_RS00190 (QAD57_00190) | - | 48152..48836 (-) | 685 | Protein_38 | type I restriction endonuclease | - |
| QAD57_RS00195 (QAD57_00195) | - | 48884..50779 (-) | 1896 | WP_286445840.1 | motility associated factor glycosyltransferase family protein | - |
| QAD57_RS00200 (QAD57_00200) | - | 50805..51572 (-) | 768 | WP_286445841.1 | TerB family tellurite resistance protein | - |
| QAD57_RS00205 (QAD57_00205) | - | 51582..51896 (-) | 315 | WP_024117443.1 | hypothetical protein | - |
| QAD57_RS00210 (QAD57_00210) | - | 51898..53385 (-) | 1488 | WP_286445842.1 | DUF5644 domain-containing protein | - |
| QAD57_RS00215 (QAD57_00215) | - | 53397..53897 (-) | 501 | WP_015645271.1 | hypothetical protein | - |
| QAD57_RS00220 (QAD57_00220) | - | 53882..55618 (-) | 1737 | WP_286445845.1 | M3 family oligoendopeptidase | - |
| QAD57_RS00225 (QAD57_00225) | - | 55718..56968 (-) | 1251 | WP_199492616.1 | cation:proton antiporter | - |
| QAD57_RS00230 (QAD57_00230) | - | 57121..57303 (-) | 183 | WP_231170333.1 | hypothetical protein | - |
| QAD57_RS00235 (QAD57_00235) | - | 57287..57847 (-) | 561 | WP_000595776.1 | outer membrane beta-barrel protein | - |
| QAD57_RS07720 | - | 57891..58057 (-) | 167 | Protein_48 | orotate phosphoribosyltransferase | - |
| QAD57_RS00240 (QAD57_00240) | modA | 58086..58837 (+) | 752 | Protein_49 | molybdate ABC transporter substrate-binding protein | - |
| QAD57_RS00245 (QAD57_00245) | modB | 58859..59524 (+) | 666 | Protein_50 | molybdate ABC transporter permease subunit | - |
| QAD57_RS00250 (QAD57_00250) | - | 59521..60318 (+) | 798 | WP_286445846.1 | sulfate/molybdate ABC transporter ATP-binding protein | - |
| QAD57_RS00255 (QAD57_00255) | - | 60345..60437 (+) | 93 | Protein_52 | metalloprotease | - |
| QAD57_RS00260 (QAD57_00260) | gltX | 60487..61878 (-) | 1392 | WP_286445847.1 | glutamate--tRNA ligase | - |
| QAD57_RS00265 (QAD57_00265) | hopJ | 61997..63097 (+) | 1101 | WP_286445848.1 | Hop family outer membrane protein HopJ/HopK | - |
| QAD57_RS00270 (QAD57_00270) | - | 63106..64743 (+) | 1638 | WP_286445849.1 | class I SAM-dependent methyltransferase | - |
| QAD57_RS00275 (QAD57_00275) | - | 64709..65557 (+) | 849 | WP_286445850.1 | glycosyltransferase family 9 protein | - |
| QAD57_RS00280 (QAD57_00280) | typA | 65603..67402 (+) | 1800 | WP_286445851.1 | translational GTPase TypA | - |
| QAD57_RS00285 (QAD57_00285) | - | 67418..68347 (+) | 930 | WP_286445852.1 | DNA adenine methylase | - |
| QAD57_RS00290 (QAD57_00290) | - | 68350..68973 (+) | 624 | WP_050831459.1 | GIY-YIG nuclease family protein | - |
| QAD57_RS00295 (QAD57_00295) | - | 69068..70126 (+) | 1059 | WP_286445853.1 | DNA cytosine methyltransferase | - |
| QAD57_RS00300 (QAD57_00300) | - | 70116..70868 (+) | 753 | WP_286445854.1 | restriction endonuclease | - |
| QAD57_RS00305 (QAD57_00305) | - | 71105..72049 (-) | 945 | WP_286445855.1 | catalase | - |
| QAD57_RS00310 (QAD57_00310) | hofC | 72330..73916 (+) | 1587 | WP_286445856.1 | outer membrane beta-barrel protein HofC | - |
| QAD57_RS00315 (QAD57_00315) | hofD | 73991..75388 (+) | 1398 | WP_286445857.1 | outer membrane beta-barrel protein HofD | - |
| QAD57_RS00320 (QAD57_00320) | - | 75580..76221 (+) | 642 | WP_286445858.1 | hypothetical protein | - |
| QAD57_RS00325 (QAD57_00325) | - | 76245..78979 (+) | 2735 | Protein_66 | DUF3519 domain-containing protein | - |
| QAD57_RS00330 (QAD57_00330) | - | 79492..80223 (-) | 732 | WP_180393783.1 | NYN domain-containing protein | - |
| QAD57_RS00335 (QAD57_00335) | ruvC | 80356..80829 (+) | 474 | WP_001221180.1 | crossover junction endodeoxyribonuclease RuvC | - |
| QAD57_RS00340 (QAD57_00340) | - | 80830..83203 (-) | 2374 | Protein_69 | TonB-dependent receptor | - |
| QAD57_RS00345 (QAD57_00345) | - | 83526..85043 (+) | 1518 | WP_286445859.1 | catalase | - |
| QAD57_RS00350 (QAD57_00350) | - | 85194..86069 (+) | 876 | WP_286445860.1 | twin-arginine translocation signal domain-containing protein | - |
| QAD57_RS00355 (QAD57_00355) | - | 86154..86369 (+) | 216 | WP_001206520.1 | hypothetical protein | - |
| QAD57_RS00360 (QAD57_00360) | - | 86427..86756 (-) | 330 | WP_001153399.1 | zinc ribbon domain-containing protein YjdM | - |
| QAD57_RS00365 (QAD57_00365) | cdh | 86940..87838 (+) | 899 | Protein_74 | CDP-diacylglycerol diphosphatase | - |
| QAD57_RS00370 (QAD57_00370) | flgE | 88048..90204 (+) | 2157 | WP_000946418.1 | flagellar hook protein FlgE | - |
| QAD57_RS00375 (QAD57_00375) | hypA | 90263..90616 (+) | 354 | WP_000545288.1 | hydrogenase/urease nickel incorporation protein HypA | - |
| QAD57_RS00380 (QAD57_00380) | mua | 90623..91084 (+) | 462 | WP_286445861.1 | nickel-binding protein Mua | - |
| QAD57_RS00385 (QAD57_00385) | lpxB | 91084..92166 (+) | 1083 | WP_286445862.1 | lipid-A-disaccharide synthase | - |
| QAD57_RS00390 (QAD57_00390) | greA | 92207..92701 (+) | 495 | WP_001031323.1 | transcription elongation factor GreA | - |
| QAD57_RS00395 (QAD57_00395) | dut | 92691..93128 (+) | 438 | WP_000694155.1 | dUTP diphosphatase | - |
| QAD57_RS00400 (QAD57_00400) | - | 93125..93781 (+) | 657 | WP_000022994.1 | hypothetical protein | - |
| QAD57_RS00405 (QAD57_00405) | - | 93786..95438 (+) | 1653 | WP_286445863.1 | plasminogen-binding protein pgbA C-terminal domain-containing protein | - |
| QAD57_RS00410 (QAD57_00410) | - | 95443..96114 (+) | 672 | WP_286445865.1 | type III pantothenate kinase | - |
| QAD57_RS00415 (QAD57_00415) | - | 96105..96842 (+) | 738 | WP_286445866.1 | sulfite exporter TauE/SafE family protein | - |
| QAD57_RS00420 (QAD57_00420) | gmhB | 96829..97353 (+) | 525 | WP_154404878.1 | D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase | - |
| QAD57_RS00425 (QAD57_00425) | rfaD | 97362..98354 (+) | 993 | WP_286445868.1 | ADP-glyceromanno-heptose 6-epimerase | - |
| QAD57_RS00430 (QAD57_00430) | rfaE1 | 98351..99742 (+) | 1392 | WP_286445869.1 | D-glycero-beta-D-manno-heptose-7-phosphate kinase | - |
| QAD57_RS00435 (QAD57_00435) | gmhA | 99735..100313 (+) | 579 | WP_286445870.1 | D-sedoheptulose 7-phosphate isomerase | - |
| QAD57_RS00440 (QAD57_00440) | guaC | 100480..101457 (-) | 978 | WP_172417696.1 | GMP reductase | - |
| QAD57_RS00445 (QAD57_00445) | - | 101705..103306 (+) | 1602 | WP_286445871.1 | ATP-binding cassette domain-containing protein | - |
| QAD57_RS00450 (QAD57_00450) | - | 103303..104247 (+) | 945 | WP_286445872.1 | COG2958 family protein | - |
| QAD57_RS00455 (QAD57_00455) | - | 104270..104956 (-) | 687 | WP_286445873.1 | phosphatase PAP2 family protein | - |
| QAD57_RS00460 (QAD57_00460) | - | 104974..105161 (+) | 188 | Protein_93 | type I restriction endonuclease | - |
| QAD57_RS00465 (QAD57_00465) | - | 105133..106722 (+) | 1590 | WP_286445874.1 | type I restriction-modification system subunit M | - |
| QAD57_RS00470 (QAD57_00470) | - | 106715..107968 (+) | 1254 | WP_286445875.1 | restriction endonuclease subunit S | - |
| QAD57_RS00475 (QAD57_00475) | - | 107973..110984 (+) | 3012 | WP_286445876.1 | type I restriction endonuclease subunit R | - |
Sequence
Protein
Download Length: 87 a.a. Molecular weight: 10050.98 Da Isoelectric Point: 6.9718
>NTDB_id=817286 QAD57_RS00160 WP_001177713.1 45345..45608(-) (comB3) [Helicobacter pylori strain BS07]
MQLVGISVSNLKEISSKEKFLWLNAKSFLIAGFIPFVMIPWLDFLNSLMLYVCFLLVFSIAEFFDEYISDILIAHSKIKT
KTNSFYA
MQLVGISVSNLKEISSKEKFLWLNAKSFLIAGFIPFVMIPWLDFLNSLMLYVCFLLVFSIAEFFDEYISDILIAHSKIKT
KTNSFYA
Nucleotide
Download Length: 264 bp
>NTDB_id=817286 QAD57_RS00160 WP_001177713.1 45345..45608(-) (comB3) [Helicobacter pylori strain BS07]
ATGCAATTAGTCGGCATTTCAGTTTCTAATCTCAAAGAAATCAGTTCTAAAGAAAAGTTTCTTTGGCTCAATGCTAAGAG
CTTTTTAATCGCAGGATTTATTCCTTTTGTAATGATACCTTGGCTAGATTTTTTAAATTCTTTAATGCTGTATGTGTGCT
TTTTATTGGTTTTTAGCATAGCGGAGTTCTTTGATGAATATATAAGCGACATTTTAATCGCCCATTCTAAGATTAAAACC
AAAACTAATTCATTTTATGCTTAA
ATGCAATTAGTCGGCATTTCAGTTTCTAATCTCAAAGAAATCAGTTCTAAAGAAAAGTTTCTTTGGCTCAATGCTAAGAG
CTTTTTAATCGCAGGATTTATTCCTTTTGTAATGATACCTTGGCTAGATTTTTTAAATTCTTTAATGCTGTATGTGTGCT
TTTTATTGGTTTTTAGCATAGCGGAGTTCTTTGATGAATATATAAGCGACATTTTAATCGCCCATTCTAAGATTAAAACC
AAAACTAATTCATTTTATGCTTAA
Domains
No domain identified.
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comB3 | Helicobacter pylori 26695 |
58.621 |
100 |
0.586 |