Detailed information    

insolico Bioinformatically predicted

Overview


Name   cipB   Type   Regulator
Locus tag   R8563_RS02535 Genome accession   NZ_AP026917
Coordinates   491986..492135 (+) Length   49 a.a.
NCBI ID   WP_001818346.1    Uniprot ID   Q9FBH1
Organism   Streptococcus pneumoniae strain PZ900700007     
Function   indirect induction of ComX; activation of comRS system (predicted from homology)   
Competence regulation

Genomic Context


Location: 486986..497135
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8563_RS02485 (PC0007_04800) blpI 487898..488095 (+) 198 WP_001093259.1 bacteriocin-like peptide BlpI -
  R8563_RS02490 (PC0007_04820) blpJ 488561..488830 (+) 270 WP_001093249.1 bacteriocin-like peptide BlpJ -
  R8563_RS02500 (PC0007_04830) - 488899..489128 (+) 230 Protein_491 Blp family class II bacteriocin -
  R8563_RS02505 - 489131..489250 (+) 120 WP_000346298.1 PncF family bacteriocin immunity protein -
  R8563_RS02510 (PC0007_04840) - 489547..489711 (+) 165 WP_000727118.1 hypothetical protein -
  R8563_RS02515 (PC0007_04850) - 489708..490112 (+) 405 WP_000846943.1 hypothetical protein -
  R8563_RS02520 - 490315..491119 (+) 805 WP_151394153.1 IS5 family transposase -
  R8563_RS02525 (PC0007_04880) blpM 491269..491523 (+) 255 WP_000379879.1 two-peptide bacteriocin subunit BlpM -
  R8563_RS02530 (PC0007_04890) blpN 491539..491742 (+) 204 WP_001099492.1 two-peptide bacteriocin subunit BlpN -
  R8563_RS02535 (PC0007_04900) cipB 491986..492135 (+) 150 WP_001818346.1 bacteriocin-like peptide BlpO Regulator
  R8563_RS10835 - 492171..492236 (+) 66 Protein_499 ComC/BlpC family peptide pheromone/bacteriocin -
  R8563_RS02540 - 492239..492358 (+) 120 WP_000346296.1 PncF family bacteriocin immunity protein -
  R8563_RS02545 (PC0007_04920) - 493144..493527 (+) 384 WP_000877381.1 hypothetical protein -
  R8563_RS02550 (PC0007_04930) - 493579..494268 (+) 690 WP_000760529.1 CPBP family intramembrane glutamic endopeptidase -
  R8563_RS02555 (PC0007_04940) blpZ 494310..494543 (+) 234 WP_001849865.1 immunity protein BlpZ -
  R8563_RS02560 - 494694..495305 (+) 612 WP_000394037.1 CPBP family intramembrane glutamic endopeptidase -
  R8563_RS02565 (PC0007_04950) ccrZ 495466..496260 (+) 795 WP_000363010.1 cell cycle regulator CcrZ -
  R8563_RS02570 (PC0007_04960) trmB 496257..496892 (+) 636 WP_001266078.1 tRNA (guanosine(46)-N7)-methyltransferase TrmB -

Sequence


Protein


Download         Length: 49 a.a.        Molecular weight: 5134.91 Da        Isoelectric Point: 3.9133

>NTDB_id=81694 R8563_RS02535 WP_001818346.1 491986..492135(+) (cipB) [Streptococcus pneumoniae strain PZ900700007]
MDTKMMSQFAVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDGCATTV

Nucleotide


Download         Length: 150 bp        

>NTDB_id=81694 R8563_RS02535 WP_001818346.1 491986..492135(+) (cipB) [Streptococcus pneumoniae strain PZ900700007]
ATGGATACAAAAATGATGTCACAATTTGCAGTTATGGATAATGAAATGCTTGCTTGCGTTGAAGGTGGAGATATTGATTG
GGGAAGAAAAATTAGTTGTGCAGCAGGGGTTGCATATGGCGCAATTGATGGGTGTGCAACAACGGTTTGA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB Q9FBH1

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cipB Streptococcus mutans UA159

51.02

100

0.51


Multiple sequence alignment