Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   R3H37_RS05395 Genome accession   NZ_CP136948
Coordinates   1081370..1081846 (-) Length   158 a.a.
NCBI ID   WP_002984880.1    Uniprot ID   A0A0H2UU18
Organism   Streptococcus pyogenes strain Spyo01     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1076370..1086846
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R3H37_RS05380 (R3H37_05380) fbp54 1077183..1078835 (+) 1653 WP_129284059.1 Rqc2 family fibronectin-binding protein Fbp54 -
  R3H37_RS05385 (R3H37_05385) - 1078894..1080141 (-) 1248 WP_129284060.1 tetratricopeptide repeat protein -
  R3H37_RS05390 (R3H37_05390) - 1080131..1081312 (-) 1182 WP_002990002.1 AI-2E family transporter -
  R3H37_RS05395 (R3H37_05395) mutX 1081370..1081846 (-) 477 WP_002984880.1 NUDIX hydrolase Machinery gene
  R3H37_RS05400 (R3H37_05400) rfbB 1082067..1083107 (-) 1041 WP_002984881.1 dTDP-glucose 4,6-dehydratase -
  R3H37_RS05405 (R3H37_05405) - 1083352..1083945 (-) 594 WP_002990099.1 dTDP-4-dehydrorhamnose 3,5-epimerase family protein -
  R3H37_RS05410 (R3H37_05410) rfbA 1083945..1084814 (-) 870 WP_014407521.1 glucose-1-phosphate thymidylyltransferase RfbA -
  R3H37_RS05415 (R3H37_05415) - 1084872..1085981 (-) 1110 WP_136038604.1 NAD(P)/FAD-dependent oxidoreductase -
  R3H37_RS05420 (R3H37_05420) - 1086021..1086809 (-) 789 WP_002984887.1 Nif3-like dinuclear metal center hexameric protein -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18462.68 Da        Isoelectric Point: 4.3268

>NTDB_id=816455 R3H37_RS05395 WP_002984880.1 1081370..1081846(-) (mutX) [Streptococcus pyogenes strain Spyo01]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=816455 R3H37_RS05395 WP_002984880.1 1081370..1081846(-) (mutX) [Streptococcus pyogenes strain Spyo01]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAGGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCCGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTCCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UU18

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

70.253

100

0.703