Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   QCM40_RS06120 Genome accession   NZ_CP122516
Coordinates   1258008..1259792 (+) Length   594 a.a.
NCBI ID   WP_279954601.1    Uniprot ID   -
Organism   Helicobacter pylori strain HP34     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1253008..1264792
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QCM40_RS06090 (QCM40_06090) motB 1253671..1254438 (+) 768 WP_001085304.1 flagellar motor protein MotB -
  QCM40_RS06095 (QCM40_06095) - 1254442..1254879 (+) 438 WP_134889861.1 hypothetical protein -
  QCM40_RS06100 (QCM40_06100) - 1255058..1256719 (+) 1662 WP_279954573.1 ABC transporter permease/substrate-binding protein -
  QCM40_RS06105 (QCM40_06105) - 1256722..1257363 (+) 642 WP_279954576.1 ATP-binding cassette domain-containing protein -
  QCM40_RS06110 (QCM40_06110) - 1257375..1257554 (-) 180 WP_000468796.1 hypothetical protein -
  QCM40_RS06115 (QCM40_06115) - 1257546..1258007 (+) 462 WP_039704604.1 hypothetical protein -
  QCM40_RS06120 (QCM40_06120) uvrC 1258008..1259792 (+) 1785 WP_279954601.1 excinuclease ABC subunit UvrC Machinery gene
  QCM40_RS06125 (QCM40_06125) - 1259803..1261068 (+) 1266 WP_120926755.1 homoserine dehydrogenase -
  QCM40_RS06130 (QCM40_06130) - 1261069..1261413 (+) 345 WP_001211699.1 YraN family protein -
  QCM40_RS06135 (QCM40_06135) trxA 1261506..1261826 (+) 321 WP_000020199.1 thioredoxin -
  QCM40_RS06140 (QCM40_06140) trxB 1261832..1262767 (+) 936 WP_120926753.1 thioredoxin-disulfide reductase -
  QCM40_RS06145 (QCM40_06145) - 1262982..1263803 (+) 822 WP_279954639.1 glycosyltransferase family 25 protein -
  QCM40_RS06150 (QCM40_06150) - 1264024..1264272 (-) 249 WP_097682728.1 RNA-binding protein -
  QCM40_RS07780 - 1264423..1264617 (+) 195 Protein_1212 hypothetical protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68852.11 Da        Isoelectric Point: 9.7467

>NTDB_id=816270 QCM40_RS06120 WP_279954601.1 1258008..1259792(+) (uvrC) [Helicobacter pylori strain HP34]
MADLLSSLKNLSNSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIRNNEITPNHRTSLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYSKIAKECLEMIENKDKLVKELELKMERLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYSGSHKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQDFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEVRSLFKLECMPYRVEIFDT
SHHANSQCVGGMVVYENHEFQKNSYRRYHLKGSNEYTQMSELLTRRALDFNKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTANDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKKMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=816270 QCM40_RS06120 WP_279954601.1 1258008..1259792(+) (uvrC) [Helicobacter pylori strain HP34]
ATGGCTGATTTATTATCCAGTTTGAAAAACCTTTCTAATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCCATCCGTAATAATGAAATCACGCCAA
ACCATCGCACCAGCTTACGAATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTGATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGATGATAAAACTTA
CCCTTATATTTATATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAAGATATTTTAGACAGCTTGTATGAATTGCTCCCATTGGTTCAAAAGAAA
AATTGCATCAAAGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTCAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCGTCAAAGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCTCTCATTTATAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATAGTGGGAGCCATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTTAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTGATGCCAGAACAAATCTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGATTTTATCTCTCACCAATACTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGTGCGATCGCTCTTTAAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGAATTTCAAAAAAACTCCTATCGGCG
CTACCATTTAAAAGGCTCTAACGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGATTTTAATAAAGAGC
CACCACCTAATTTGTGGGTGATCGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGAGGTGCTAAAGACATCAT
CCACACCGCTAACGATACTTTTAAATTGCTCCCCAGCGACAAGCGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAAAATGAAACAAATCGCGCTTTTAAAAGAAAAGGGTATA
GGAGAAGCCAGCGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCTGTTTTAAAAAAACGAATCTAA

Domains

Predicted by InterproScan.

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

UvrB/uvrC motif (UVR)

(205-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.633

100

0.966