Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   QCM05_RS07270 Genome accession   NZ_CP122515
Coordinates   1510010..1511794 (+) Length   594 a.a.
NCBI ID   WP_279962927.1    Uniprot ID   -
Organism   Helicobacter pylori strain HP22     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1505010..1516794
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QCM05_RS07235 (QCM05_07235) motA 1505080..1505853 (+) 774 WP_000366185.1 flagellar motor stator protein MotA -
  QCM05_RS07240 (QCM05_07240) motB 1505856..1506623 (+) 768 WP_001085315.1 flagellar motor protein MotB -
  QCM05_RS07245 (QCM05_07245) - 1506627..1507064 (+) 438 WP_001031792.1 hypothetical protein -
  QCM05_RS07250 (QCM05_07250) - 1507164..1508720 (+) 1557 WP_140446387.1 ABC transporter permease/substrate-binding protein -
  QCM05_RS07255 (QCM05_07255) - 1508724..1509365 (+) 642 WP_140446386.1 ATP-binding cassette domain-containing protein -
  QCM05_RS07260 (QCM05_07260) - 1509377..1509556 (-) 180 WP_000468796.1 hypothetical protein -
  QCM05_RS07265 (QCM05_07265) - 1509548..1510009 (+) 462 WP_039704604.1 hypothetical protein -
  QCM05_RS07270 (QCM05_07270) uvrC 1510010..1511794 (+) 1785 WP_279962927.1 excinuclease ABC subunit UvrC Machinery gene
  QCM05_RS07275 (QCM05_07275) - 1511805..1513070 (+) 1266 WP_279962929.1 homoserine dehydrogenase -
  QCM05_RS07280 (QCM05_07280) - 1513071..1513415 (+) 345 WP_120847080.1 YraN family protein -
  QCM05_RS07285 (QCM05_07285) trxA 1513504..1513824 (+) 321 WP_048944868.1 thioredoxin -
  QCM05_RS07290 (QCM05_07290) trxB 1513830..1514765 (+) 936 WP_279962931.1 thioredoxin-disulfide reductase -
  QCM05_RS07295 (QCM05_07295) - 1514928..1515749 (+) 822 WP_279962932.1 glycosyltransferase family 25 protein -
  QCM05_RS07300 (QCM05_07300) - 1515960..1516208 (-) 249 WP_000790557.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68729.06 Da        Isoelectric Point: 9.6558

>NTDB_id=816250 QCM05_RS07270 WP_279962927.1 1510010..1511794(+) (uvrC) [Helicobacter pylori strain HP22]
MADLLSSLKNLSHSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSVRNNEITPNHRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDKLIKELELKMECLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGKGHKAVLVKMFMRGGKIISSAFEKIYSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQDFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFKLECMPYRVEIFDA
SHHANSQCVGGMVVYENHEFQKNSYRRYHLKGSNEYTQMSELLTRRALDFNKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTASDTFKLLPSDKRLQWVQKLRDESHRYAISFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=816250 QCM05_RS07270 WP_279962927.1 1510010..1511794(+) (uvrC) [Helicobacter pylori strain HP22]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTCATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGTTATTTTTCTGTCCGCAATAATGAAATCACGCCCA
ATCATCGTGCAAGCTTACGCATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTGAGAGATGATAAAACTTA
CCCTTATATTTATATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGTGGGGCTAAGGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAAGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTGAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTAA
AAATGGAGTGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTCATTTATAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATGGCAAGGGCCATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCTACTCTCTCAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTAATGCCTGAACAGATCTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGATTTTATCTCTCACCAATACTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCGATCGCTTTTTAAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGATGCA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGAATTTCAAAAAAACTCTTATCGGCG
CTACCATTTAAAAGGCTCTAATGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGATTTTAATAAAGAGC
CACCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGCGCTAAAGACATTAT
CCATACCGCTAGCGATACTTTTAAATTACTCCCTAGCGACAAGCGCTTGCAGTGGGTGCAAAAATTGCGTGATGAAAGCC
ACCGGTATGCGATAAGCTTCCATAGATCCACTAAACTTAAAAACATGAAGCAAATCGCTCTTTTAAAAGAAAAGGGCATA
GGAGAAGCCAGCGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCAAGCGAGCAGGAAAAAAA
CGCTGTTTTAAAAAAACGAATCTAA

Domains

Predicted by InterproScan.

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

UvrB/uvrC motif (UVR)

(205-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.633

100

0.966