Detailed information NTG0816191

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: R1T12_RS02305
• Genome accession: NZ_CP136909
• Coordinates: 500460..503255 (+)
• Length: 931 a.a.
• NCBI ID: WP_019484383.1
• Uniprot ID: -
• Organism: Pseudomonas aeruginosa PA103
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 495460..508255

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R1T12_RS02285 (R1T12_02285)	dbpA	495941..497317 (-)	1377	WP_003084703.1	ATP-dependent RNA helicase DbpA	-
R1T12_RS02290 (R1T12_02290)	-	497665..497874 (+)	210	WP_003084710.1	cold-shock protein	-
R1T12_RS02295 (R1T12_02295)	-	498025..498549 (+)	525	WP_003117916.1	ATP-dependent zinc protease	-
R1T12_RS02300 (R1T12_02300)	mdtD	498652..500085 (-)	1434	WP_003084717.1	multidrug transporter subunit MdtD	-
R1T12_RS02305 (R1T12_02305)	clpC	500460..503255 (+)	2796	WP_019484383.1	AAA family protein disaggregase ClpG	Regulator
R1T12_RS02310 (R1T12_02310)	-	503357..503935 (+)	579	WP_003084725.1	DUF2780 domain-containing protein	-
R1T12_RS02315 (R1T12_02315)	-	504375..505262 (-)	888	WP_003129039.1	acyltransferase	-
R1T12_RS02320 (R1T12_02320)	-	505405..505914 (+)	510	WP_003084733.1	ATP-dependent zinc protease	-
R1T12_RS02325 (R1T12_02325)	creB	505999..506688 (+)	690	WP_019484382.1	two-component system response regulator CreB	-
R1T12_RS02330 (R1T12_02330)	creC	506688..508112 (+)	1425	WP_003084735.1	two-component system sensor histidine kinase CreC	-

Sequence

Protein

• Length: 931 a.a.
• Molecular weight: 103370.92 Da
• Isoelectric Point: 6.8717

>NTDB_id=816191 R1T12_RS02305 WP_019484383.1 500460..503255(+) (clpC) [Pseudomonas aeruginosa PA103]
MAQELCAICHERPAVARVSLVQNGQRRELALCELHYRQLMRQQRMRSPLESLFGGGSPFDEIFSGFGEQSPVTPVRAREP
EAVDIAEYFSKQTTEYLQRAAQVAAEFGKREVDTEHLLYALADADVVQAVLKQFGLSPADLKQYIEANAMRGASKGEASE
DMTISPRVKSALQHAFALSRELGHSYVGPEHLLLGLAAVPDSFAGTLLKKYGLTEQALRQKAVKVVGKGAEDGRVDGPSN
TPQLDKFSRDLTRLAREGKLDPVIGRSKEVETTIEVLARRKKNNPVLIGEPGVGKTAIVEGLAQRMVQGEVPEVLRDKRL
VELNINAMVAGAKYRGEFEERLKQVMDELQAAQSEIILFIDEVHTIVGAGQGGGEGGLDVANVLKPAMARGEMNLIGATT
LNEYQKYIEKDAALERRFQPVFVPEPTVEQTISILRGLRDKLEGHHKVTIRDEAFVAAAELSDRYIGNRFLPDKAIDLID
QAAARVRIASTSRPAEIQELEAELAQLKREQDYAASRKWYDEAKVFEKRIQERKEHLEQITERWQQTQGSKTEEVRVEDI
AEIISKLTGIPVTELTAEEREKLLQMEERLHQRVIGQQEAITAVSDAVRLARAGLRQGSRPIATFLFLGPTGVGKTELAK
ALAEVVFGDEDAMIRIDMSEYMERHAVSRLIGAPPGYVGYDEGGQLTERVRRRPYSVILLDEIEKAHADVNNILLQVFDD
GRLTDGKGRVVDFTNTIIIATSNLGSELIMKNAQAGEFAQPPEKLKRELMTTLRGHFRPEFLNRLDEVIVFESLSKAQIE
DIVRLQLERVKRAAHAQDIYLHIDDSLVGHLAEEAYQPEFGARELKRQIRQQLETRLATAMLKGEVKEGETVTFFYDAKD
GVGYRKGAAPKPAARKKSGAGETPRGRATAARKPAKKGAAAKGKADKPKAK

Nucleotide

• Length: 2796 bp

>NTDB_id=816191 R1T12_RS02305 WP_019484383.1 500460..503255(+) (clpC) [Pseudomonas aeruginosa PA103]
ATGGCCCAGGAACTTTGCGCTATCTGCCACGAACGTCCCGCCGTCGCCCGCGTCAGCCTGGTACAGAACGGCCAGCGCCG
CGAACTCGCTCTCTGCGAACTGCATTACCGCCAGTTGATGCGCCAGCAGCGCATGCGCTCGCCGCTAGAGTCGCTGTTCG
GCGGCGGCAGCCCGTTCGACGAGATCTTCTCCGGCTTCGGCGAGCAGAGCCCGGTCACCCCGGTGCGCGCCCGCGAGCCG
GAGGCGGTGGACATCGCCGAGTACTTCAGCAAGCAGACCACCGAGTACCTGCAACGCGCCGCGCAGGTCGCCGCCGAATT
CGGCAAGCGCGAAGTGGACACCGAGCACCTGCTCTACGCCCTGGCCGACGCCGACGTGGTGCAGGCGGTGCTCAAGCAGT
TCGGCCTGTCGCCGGCCGACCTCAAGCAGTACATCGAGGCCAACGCCATGCGCGGCGCCAGCAAGGGCGAGGCGAGCGAG
GACATGACCATCTCGCCACGGGTGAAGAGCGCCTTGCAGCATGCCTTCGCCCTGTCCCGCGAACTCGGCCACAGCTATGT
CGGCCCCGAGCACCTGTTGCTCGGCCTGGCAGCGGTGCCGGACAGCTTCGCCGGGACGCTCCTGAAGAAGTACGGCCTGA
CCGAGCAGGCGCTACGGCAGAAAGCGGTCAAGGTGGTCGGCAAGGGCGCCGAGGACGGCCGCGTGGACGGCCCGAGCAAC
ACTCCGCAACTGGACAAGTTCAGCCGCGACCTGACCCGGCTGGCCCGCGAAGGCAAGCTCGATCCGGTGATCGGCCGCTC
GAAGGAAGTCGAGACCACCATCGAGGTGCTCGCCCGGCGCAAGAAGAACAACCCGGTGCTGATCGGCGAGCCCGGCGTCG
GCAAGACCGCCATCGTCGAAGGCCTGGCCCAGCGCATGGTCCAGGGCGAGGTGCCGGAGGTGCTGCGCGACAAGCGTCTG
GTCGAACTGAACATCAACGCCATGGTCGCCGGCGCCAAGTACCGCGGCGAGTTCGAGGAACGCCTCAAGCAGGTGATGGA
CGAACTGCAGGCGGCGCAGAGCGAGATCATCCTGTTCATCGACGAGGTGCACACCATCGTCGGTGCCGGCCAGGGCGGCG
GCGAAGGCGGGCTGGACGTGGCCAACGTGCTGAAGCCGGCGATGGCGCGCGGCGAGATGAACCTGATCGGCGCCACCACC
CTCAACGAGTACCAGAAGTACATCGAGAAGGACGCCGCGCTGGAGCGGCGCTTCCAGCCGGTGTTCGTCCCCGAGCCGAC
GGTGGAGCAGACCATCTCCATCCTCCGTGGCCTGCGCGACAAGCTCGAAGGCCACCACAAGGTGACCATCCGCGACGAGG
CCTTCGTCGCCGCCGCCGAGCTGTCCGACCGCTACATCGGCAACCGTTTCCTGCCGGACAAGGCCATCGACCTGATCGAC
CAGGCCGCCGCCCGCGTGCGCATCGCCAGCACCTCGCGGCCGGCCGAGATCCAGGAACTGGAGGCCGAGCTGGCGCAGCT
CAAGCGCGAGCAGGACTACGCCGCCAGCCGCAAGTGGTACGACGAGGCGAAGGTCTTCGAGAAACGCATCCAGGAACGCA
AGGAACACCTCGAGCAGATCACCGAGCGCTGGCAGCAGACCCAGGGGTCGAAGACCGAGGAGGTGCGGGTCGAGGACATC
GCCGAGATCATCTCCAAGCTCACCGGCATCCCGGTCACCGAACTGACCGCCGAGGAGCGCGAGAAGCTCCTGCAGATGGA
AGAGCGCCTGCACCAGCGGGTGATCGGCCAGCAGGAAGCGATCACCGCGGTCAGCGACGCCGTGCGCCTGGCCCGCGCCG
GGCTGCGCCAGGGCAGCCGGCCGATCGCCACCTTCCTGTTCCTCGGCCCGACCGGGGTGGGCAAGACCGAGCTGGCCAAG
GCCTTGGCCGAGGTGGTGTTCGGCGACGAAGACGCGATGATCCGCATCGACATGAGCGAATACATGGAGCGCCACGCGGT
GTCCCGGCTGATCGGTGCGCCGCCGGGCTACGTCGGCTACGACGAGGGCGGCCAGCTCACCGAGCGGGTGCGCCGGCGGC
CGTACAGCGTGATCCTGCTCGACGAGATCGAGAAGGCCCACGCCGACGTCAACAACATCCTCCTGCAGGTGTTCGACGAC
GGCCGCCTGACCGACGGCAAGGGGCGCGTGGTGGACTTCACCAACACCATCATCATCGCCACCAGCAACCTCGGCTCCGA
GCTGATCATGAAGAACGCCCAGGCCGGCGAGTTCGCCCAGCCGCCGGAGAAGCTCAAGCGCGAACTGATGACTACCCTGC
GCGGGCATTTCCGCCCGGAATTCCTCAACCGCCTCGACGAGGTGATCGTCTTCGAATCGTTGAGCAAGGCGCAGATCGAG
GACATCGTGCGCCTGCAACTGGAGCGGGTGAAGCGCGCCGCGCACGCCCAGGACATCTACCTGCACATCGACGACAGCCT
GGTCGGCCACCTCGCCGAAGAGGCCTACCAGCCGGAGTTCGGCGCCCGCGAACTGAAGCGGCAGATCCGCCAGCAACTGG
AGACGCGCCTGGCCACGGCGATGCTCAAGGGCGAGGTGAAGGAGGGCGAGACGGTCACCTTCTTCTACGACGCCAAGGAC
GGCGTCGGCTACCGCAAGGGCGCCGCGCCGAAGCCGGCGGCACGCAAGAAGTCCGGTGCCGGCGAGACGCCCAGGGGCCG
CGCGACGGCGGCGAGGAAGCCGGCGAAGAAAGGCGCCGCCGCCAAGGGCAAGGCCGACAAGCCGAAGGCCAAGTGA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (427-524)

• AAA domain (Cdc48 subfamily) (AAA_2) (620-788)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (100-147)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (175-226)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (794-873)

• ATPase family associated with various cellular activities (AAA) (AAA) (286-419)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	50.374	86.144	0.434
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	45.113	85.714	0.387
clpC	Streptococcus thermophilus LMD-9	42.563	88.829	0.378
clpC	Streptococcus thermophilus LMG 18311	42.322	88.829	0.376
clpC	Streptococcus mutans UA159	41.505	88.507	0.367