Detailed information NTG0816115

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: QAO53_RS10510
• Genome accession: NZ_CP122491
• Coordinates: 2144348..2145235 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain BE-MSSA3
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2139348..2150235

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QAO53_RS10480 (QAO53_10450)	-	2140079..2140840 (+)	762	WP_000323451.1	alpha/beta hydrolase	-
QAO53_RS10485 (QAO53_10455)	-	2141086..2141541 (+)	456	WP_000106184.1	MarR family winged helix-turn-helix transcriptional regulator	-
QAO53_RS10490 (QAO53_10460)	-	2141663..2141764 (+)	102	WP_000731972.1	SE2200 family small protein	-
QAO53_RS10495 (QAO53_10465)	-	2141824..2143248 (-)	1425	WP_000953731.1	alkaline phosphatase	-
QAO53_RS10500 (QAO53_10470)	-	2143446..2143646 (+)	201	WP_000604723.1	hypothetical protein	-
QAO53_RS10505 (QAO53_10475)	braR	2143672..2144337 (+)	666	WP_000697883.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
QAO53_RS10510 (QAO53_10480)	braS	2144348..2145235 (+)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
QAO53_RS10515 (QAO53_10485)	-	2145343..2146098 (+)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
QAO53_RS10520 (QAO53_10490)	-	2146095..2148095 (+)	2001	WP_053014809.1	ABC transporter permease	-
QAO53_RS10525 (QAO53_10495)	-	2148759..2148872 (+)	114	WP_072384844.1	hypothetical protein	-
QAO53_RS10530 (QAO53_10500)	-	2149254..2149514 (+)	261	WP_072434822.1	hypothetical protein	-
QAO53_RS10535 (QAO53_10505)	-	2149524..2150021 (+)	498	WP_001065267.1	glutathione peroxidase	-
QAO53_RS10540 (QAO53_10510)	-	2150129..2150217 (-)	89	Protein_2039	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=816115 QAO53_RS10510 WP_000143420.1 2144348..2145235(+) (braS) [Staphylococcus aureus strain BE-MSSA3]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=816115 QAO53_RS10510 WP_000143420.1 2144348..2145235(+) (braS) [Staphylococcus aureus strain BE-MSSA3]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATATGTAAAAGATAATGGTATCGGTATTAGTGAGGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993