Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   QAO16_RS10870 Genome accession   NZ_CP122489
Coordinates   2161930..2163279 (+) Length   449 a.a.
NCBI ID   WP_000806249.1    Uniprot ID   -
Organism   Staphylococcus aureus strain GE-MSSA42     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 2154701..2161597 2161930..2163279 flank 333


Gene organization within MGE regions


Location: 2154701..2163279
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QAO16_RS10840 (QAO16_10830) - 2154701..2155375 (+) 675 WP_001106068.1 IS6 family transposase -
  QAO16_RS10845 (QAO16_10835) - 2155702..2157261 (+) 1560 WP_000172880.1 hypothetical protein -
  QAO16_RS10850 (QAO16_10840) - 2157416..2157685 (+) 270 WP_000875688.1 hypothetical protein -
  QAO16_RS10855 (QAO16_10845) cch1 2157685..2159472 (+) 1788 WP_111142315.1 cassette chromosome replicative helicase -
  QAO16_RS10860 (QAO16_10850) - 2159543..2159821 (+) 279 WP_001100996.1 hypothetical protein -
  QAO16_RS10865 (QAO16_10855) - 2159951..2161597 (-) 1647 WP_000277741.1 IS1182-like element ISSau3 family transposase -
  QAO16_RS10870 (QAO16_10860) ccrA 2161930..2163279 (+) 1350 WP_000806249.1 cassette chromosome recombinase CcrA Machinery gene

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 52276.93 Da        Isoelectric Point: 10.0235

>NTDB_id=816025 QAO16_RS10870 WP_000806249.1 2161930..2163279(+) (ccrA) [Staphylococcus aureus strain GE-MSSA42]
MKQAIGYLRQSTTKQQSLVAQKQAIKTLAEKHNIQHITFYSDKQSGRTDKRNGYQQITELIQQGQCDVLCCYRLNRLHRN
LKNALKLMKLCQKYHVHILSIHDGYFDMDKAFDRLKLNIFISLAELESDNIGEQVKNGLREKAKQGKLITTHAPFGYTYR
NGTFTINQDEAPTVKAIFHYYLQDYGYKKIAQYLETDDKCINRKPYQVRAIITNPNYCGRVINQYGQYDNMFPSIVSTSI
YEQAQAIRSQKHTKRTPSSNQLKQKIKCPCCGSTLTNMTIRKKNHTLRYYVCPQNLNASRFVCEFKGINAQALEASVLST
CQDFFQNQQLYSKINRTIQQQLKRQRDIETKTTLNHEQLIEKLANGKIDAETFREQTQSLHQQSKPISSISAYQIQRAFQ
NIIQQRFTLNMLYPYIDQIHITKKKMLVGIYFKNEPLNIVNQKTQSSIA

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=816025 QAO16_RS10870 WP_000806249.1 2161930..2163279(+) (ccrA) [Staphylococcus aureus strain GE-MSSA42]
ATGAAACAAGCAATAGGTTACTTACGTCAGAGCACTACAAAGCAACAATCACTAGTAGCACAGAAACAAGCCATCAAGAC
ATTAGCTGAAAAACACAATATTCAACACATCACATTTTATAGCGATAAGCAATCAGGACGCACTGATAAGCGGAATGGTT
ATCAACAAATTACTGAACTGATTCAACAAGGACAATGTGACGTACTATGTTGTTATCGCTTGAATCGACTACATCGTAAT
TTGAAAAATGCATTAAAACTTATGAAACTGTGTCAAAAATATCATGTTCATATTCTAAGTATTCATGATGGCTATTTTGA
TATGGATAAAGCGTTTGATCGCCTAAAGCTCAATATATTCATAAGCCTCGCAGAATTAGAGTCCGATAATATTGGTGAAC
AAGTCAAAAATGGCCTTCGAGAAAAAGCAAAACAAGGTAAACTGATCACAACCCATGCACCATTTGGTTATACCTATCGC
AATGGCACATTCACAATTAATCAAGATGAAGCACCAACAGTTAAGGCAATATTCCATTACTACCTACAAGACTATGGTTA
TAAGAAAATTGCGCAATACCTAGAAACAGATGATAAATGTATTAATCGTAAACCTTACCAAGTACGCGCTATTATAACGA
ATCCTAATTATTGTGGTCGCGTTATCAATCAATATGGACAATATGACAACATGTTCCCATCTATTGTTTCGACCAGTATA
TACGAACAAGCTCAAGCAATAAGGTCACAAAAACATACCAAGCGGACTCCATCATCTAATCAACTCAAACAAAAAATCAA
ATGTCCGTGTTGTGGCTCAACACTCACAAATATGACAATTAGAAAAAAGAACCATACATTACGTTATTACGTCTGTCCTC
AAAATTTGAATGCATCTCGTTTTGTCTGTGAATTCAAGGGAATCAACGCACAAGCATTAGAAGCAAGTGTCTTATCTACA
TGTCAGGATTTCTTTCAGAACCAACAGCTGTATTCAAAAATTAACCGAACAATTCAACAACAACTCAAAAGACAAAGAGA
CATAGAAACTAAAACTACACTCAATCACGAACAGCTGATAGAAAAATTGGCCAACGGCAAAATTGATGCAGAAACGTTCA
GAGAACAAACGCAATCATTACATCAACAATCAAAACCTATATCATCAATCAGTGCGTATCAAATTCAAAGAGCGTTTCAA
AACATCATTCAACAACGTTTCACGCTAAACATGTTATACCCTTATATTGATCAAATTCATATCACAAAAAAGAAAATGCT
TGTTGGCATTTATTTCAAAAATGAACCCTTAAATATCGTCAATCAAAAAACGCAATCATCGATTGCTTAA

Domains

Predicted by InterproScan.

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(262-322)

Recombinase (Recombinase)

(169-250)

Resolvase, N terminal domain (Resolvase)

(4-147)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus COL

86.414

100

0.864
  ccrA Staphylococcus aureus N315

76.837

100

0.768