Detailed information NTG0815992

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: QAY60_RS13810
• Genome accession: NZ_CP122488
• Coordinates: 2769490..2770377 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain IT-MRSA44
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2764490..2775377

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QAY60_RS13780 (QAY60_13740)	-	2764508..2764596 (+)	89	Protein_2676	hypothetical protein	-
QAY60_RS13785 (QAY60_13745)	-	2764704..2765201 (-)	498	WP_001065267.1	glutathione peroxidase	-
QAY60_RS13790 (QAY60_13750)	-	2765211..2765471 (-)	261	WP_072434822.1	hypothetical protein	-
QAY60_RS13795 (QAY60_13755)	-	2765853..2765966 (-)	114	WP_072384844.1	hypothetical protein	-
QAY60_RS13800 (QAY60_13760)	-	2766630..2768630 (-)	2001	WP_000776746.1	ABC transporter permease	-
QAY60_RS13805 (QAY60_13765)	-	2768627..2769382 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
QAY60_RS13810 (QAY60_13770)	braS	2769490..2770377 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
QAY60_RS13815 (QAY60_13775)	nsaR	2770388..2771053 (-)	666	Protein_2683	nisin susceptibility-associated two-component system response regulator NsaR	-
QAY60_RS13820 (QAY60_13780)	-	2771079..2771279 (-)	201	WP_000604723.1	hypothetical protein	-
QAY60_RS13825 (QAY60_13785)	-	2771477..2772901 (+)	1425	WP_000953731.1	alkaline phosphatase	-
QAY60_RS13830	-	2772961..2773062 (-)	102	WP_000731972.1	SE2200 family small protein	-
QAY60_RS13835 (QAY60_13795)	-	2773184..2773639 (-)	456	WP_000106184.1	MarR family winged helix-turn-helix transcriptional regulator	-
QAY60_RS13840 (QAY60_13800)	-	2773885..2774646 (-)	762	WP_000323451.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=815992 QAY60_RS13810 WP_000143420.1 2769490..2770377(-) (braS) [Staphylococcus aureus strain IT-MRSA44]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=815992 QAY60_RS13810 WP_000143420.1 2769490..2770377(-) (braS) [Staphylococcus aureus strain IT-MRSA44]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATATGTAAAAGATAATGGTATCGGTATTAGTGAGGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993