Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   R8522_RS05810 Genome accession   NZ_AP026916
Coordinates   1161924..1162388 (-) Length   154 a.a.
NCBI ID   WP_001135766.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700006     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1156924..1167388
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8522_RS05790 (PC0006_11800) - 1157875..1158843 (-) 969 WP_000105360.1 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha -
  R8522_RS05795 (PC0006_11810) pdrM 1158997..1160358 (-) 1362 WP_000278530.1 sodium-coupled multidrug efflux MATE transporter PdrM -
  R8522_RS05800 (PC0006_11820) - 1160369..1160629 (-) 261 WP_001105925.1 hypothetical protein -
  R8522_RS05805 (PC0006_11830) - 1160643..1161911 (-) 1269 WP_000924490.1 dihydroorotase -
  R8522_RS05810 (PC0006_11840) mutX 1161924..1162388 (-) 465 WP_001135766.1 8-oxo-dGTP diphosphatase Machinery gene
  R8522_RS05815 (PC0006_11850) - 1162398..1163051 (-) 654 WP_000401326.1 uracil-DNA glycosylase -
  R8522_RS05820 (PC0006_11860) - 1163187..1163789 (-) 603 WP_001811694.1 hypothetical protein -
  R8522_RS05825 (PC0006_11870) - 1163847..1164560 (-) 714 WP_000499438.1 YjjG family noncanonical pyrimidine nucleotidase -
  R8522_RS05830 (PC0006_11880) - 1164621..1165559 (-) 939 WP_001828301.1 FRG domain-containing protein -
  R8522_RS05835 (PC0006_11890) - 1165724..1165927 (-) 204 Protein_1160 transposase -
  R8522_RS05840 (PC0006_11900) - 1166012..1166386 (-) 375 WP_050123123.1 phospholipase D-like domain-containing protein -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 17842.25 Da        Isoelectric Point: 4.2287

>NTDB_id=81598 R8522_RS05810 WP_001135766.1 1161924..1162388(-) (mutX) [Streptococcus pneumoniae strain PZ900700006]
MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGETPQECAAREILEETGLKAKPVLKGVITFPEFTPDLD
WYTYVFKVTEFEGDLIDCNEGMLEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE

Nucleotide


Download         Length: 465 bp        

>NTDB_id=81598 R8522_RS05810 WP_001135766.1 1161924..1162388(-) (mutX) [Streptococcus pneumoniae strain PZ900700006]
ATGCCTCAGTTAGCGACGATTTGCTACATTGATAATGGGAAAGAACTGCTCATGCTCCATCGTAATAAGAAACCCAATGA
TGTCCATGAAGGGAAATGGATTGGTGTGGGTGGTAAGCTAGAGAGAGGAGAGACGCCCCAGGAATGCGCGGCGCGTGAAA
TCCTTGAAGAAACAGGGCTCAAAGCCAAGCCAGTTCTAAAAGGTGTCATCACTTTTCCTGAATTTACACCAGATTTAGAC
TGGTACACCTATGTTTTTAAGGTGACGGAGTTTGAGGGCGACTTGATTGACTGCAATGAGGGGATGCTAGAATGGGTTCC
CTATGATGAGGTTTTGAGCAAGCCGACTTGGGAAGGTGACCACACCTTTGTTGAGTGGCTTTTAGAGGATAAACCCTTCT
TTTCAGCCAAGTTTGTTTATGATGGGGATAAATTGTTGGATACCCAAGTTGATTTCTATGAATAA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

99.351

100

0.994

Multiple sequence alignment