Detailed information NTG0815818

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: QAY83_RS10120
• Genome accession: NZ_CP122484
• Coordinates: 2019224..2020111 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain SW-MSSA63
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2014224..2025111

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QAY83_RS10090 (QAY83_10075)	-	2014243..2014335 (+)	93	WP_010956583.1	hypothetical protein	-
QAY83_RS10095 (QAY83_10080)	-	2014443..2014940 (-)	498	WP_001065268.1	glutathione peroxidase	-
QAY83_RS10100 (QAY83_10085)	-	2014950..2015210 (-)	261	WP_001791974.1	hypothetical protein	-
QAY83_RS10105 (QAY83_10090)	-	2015592..2015705 (-)	114	Protein_1961	hypothetical protein	-
QAY83_RS10110 (QAY83_10095)	-	2016364..2018364 (-)	2001	WP_000776740.1	ABC transporter permease	-
QAY83_RS10115 (QAY83_10100)	-	2018361..2019116 (-)	756	WP_411905936.1	ABC transporter ATP-binding protein	-
QAY83_RS10120 (QAY83_10105)	braS	2019224..2020111 (-)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
QAY83_RS10125 (QAY83_10110)	braR	2020122..2020787 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
QAY83_RS10130 (QAY83_10115)	-	2020813..2021013 (-)	201	WP_000604727.1	hypothetical protein	-
QAY83_RS10135 (QAY83_10120)	-	2021211..2022635 (+)	1425	WP_000953748.1	alkaline phosphatase	-
QAY83_RS10140	-	2022695..2022796 (-)	102	WP_000731972.1	SE2200 family small protein	-
QAY83_RS10145 (QAY83_10130)	-	2022918..2023373 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
QAY83_RS10150 (QAY83_10135)	-	2023618..2024379 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=815818 QAY83_RS10120 WP_000143417.1 2019224..2020111(-) (braS) [Staphylococcus aureus strain SW-MSSA63]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=815818 QAY83_RS10120 WP_000143417.1 2019224..2020111(-) (braS) [Staphylococcus aureus strain SW-MSSA63]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99