Detailed information NTG0815650

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: RYQ61_RS03530
• Genome accession: NZ_CP136799
• Coordinates: 665942..668500 (-)
• Length: 852 a.a.
• NCBI ID: WP_102568415.1
• Uniprot ID: -
• Organism: Streptococcus intermedius strain XH2169
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 660942..673500

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RYQ61_RS03495 (RYQ61_03495)	-	661254..662081 (+)	828	WP_102568418.1	ATP-binding protein	-
RYQ61_RS03500 (RYQ61_03500)	-	662812..663252 (+)	441	WP_102568417.1	ArpU family phage packaging/lysis transcriptional regulator	-
RYQ61_RS03505 (RYQ61_03505)	-	663507..663620 (+)	114	Protein_671	phage terminase small subunit P27 family	-
RYQ61_RS03510 (RYQ61_03510)	-	663756..663947 (+)	192	WP_049508834.1	type II toxin-antitoxin system HicA family toxin	-
RYQ61_RS03515 (RYQ61_03515)	-	663983..664363 (+)	381	WP_102568416.1	type II toxin-antitoxin system HicB family antitoxin	-
RYQ61_RS03520 (RYQ61_03520)	brsR	664905..665345 (+)	441	WP_041823295.1	LytTR family DNA-binding domain-containing protein	Regulator
RYQ61_RS03525 (RYQ61_03525)	-	665342..665800 (+)	459	WP_020999243.1	DUF3021 domain-containing protein	-
RYQ61_RS03530 (RYQ61_03530)	hexA	665942..668500 (-)	2559	WP_102568415.1	DNA mismatch repair protein MutS	Machinery gene
RYQ61_RS03535 (RYQ61_03535)	argR	668663..669103 (-)	441	WP_003075336.1	arginine repressor	-
RYQ61_RS03540 (RYQ61_03540)	argS	669207..670895 (+)	1689	WP_102568414.1	arginine--tRNA ligase	-
RYQ61_RS03545 (RYQ61_03545)	nrdI	670947..671402 (-)	456	WP_020999246.1	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	-
RYQ61_RS03550 (RYQ61_03550)	-	671478..671987 (-)	510	WP_003077356.1	hypothetical protein	-

Sequence

Protein

• Length: 852 a.a.
• Molecular weight: 96049.41 Da
• Isoelectric Point: 4.8686

>NTDB_id=815650 RYQ61_RS03530 WP_102568415.1 665942..668500(-) (hexA) [Streptococcus intermedius strain XH2169]
MTKEKLSPGMQQYLDIKKDYPDAFLLFRMGDFYELFYEDAINAAQILEIALTSRNKNSEKPIPMAGVPYHSVQQYIDVLI
ESGYKVAIAEQVEDPKKAVGVVKREVVQVITPGTAVDSSKPDSQNNFLVALDKLEDFYGLAYMDVVTGEFQVTTLSDFNM
VCGEIRNLQAREVVLGYELPEAEHQVLANQMNLLLSQVETAFEDVQLLGDDLSRLEYQVAGKLLEYVHQTQLRELSHLKQ
VHHYEIKDFLQMDYATMTSLDLTENARTGKKHGSLYWLMDETKTAMGTRLLRRWIQHPLLDKERILKRQDVVQVFLDHFF
ERSDLADSLKGVYDIERLASRVSFGKTNPKDLLQLAATLSNVPQIKGILQGIDHPVLGQLIENLDDIPELANLIQSAISP
DAPNVITEGNIIQTGFDETLDKYRVVLRDGTSWIADIEAKERVASGINNLKIDYNKKDGYYFHVTNSQLEHVPSHFFRKA
TLKNSERFGTEELARIEGEMLEAREKSANLEYEIFIRIREEAGKYIKRLQSLAQTLATVDVLQSFAAVAEKQRFVRPEFI
ERPSIEIDKGRHAVVEKVMGAQTYIPNSISMDENVNLQLITGPNMSGKSTYMRQLAIIVIMAQMGSYVSAESAQLPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANHAISQATEHSLILFDELGRGTATYDGMALAQAIIEYIHNRTGAKTLFATHYHEL
TDLSTSLTQLENVHVATLEKDGKVTFLHKIEAGPADKSYGIHVARIAGLPNDLLMRADQILARLEEQANEKPSLNPSNKG
ANDSKENQVSEQISLFTETTESPILDELRQLDIYNMTPMEVMLAIAEMKKHL

Nucleotide

• Length: 2559 bp

>NTDB_id=815650 RYQ61_RS03530 WP_102568415.1 665942..668500(-) (hexA) [Streptococcus intermedius strain XH2169]
ATGACAAAAGAAAAACTATCTCCGGGAATGCAACAGTATTTAGATATAAAAAAAGATTATCCGGATGCTTTTTTGCTATT
TCGCATGGGAGATTTTTATGAATTATTCTATGAAGATGCGATCAATGCAGCACAGATTTTAGAAATTGCTCTGACTAGCC
GTAATAAAAATTCGGAAAAGCCAATCCCGATGGCAGGAGTTCCCTATCATTCGGTGCAACAATATATTGATGTTTTAATT
GAATCGGGCTATAAAGTAGCGATTGCAGAGCAGGTGGAAGATCCTAAAAAAGCAGTTGGTGTAGTCAAACGTGAGGTGGT
ACAAGTCATCACACCGGGGACAGCCGTTGATTCTTCAAAACCAGATAGTCAAAATAATTTCTTGGTAGCTTTAGATAAGC
TAGAAGATTTCTATGGGCTAGCTTATATGGATGTGGTAACTGGTGAATTTCAGGTGACAACTCTCAGTGACTTTAACATG
GTTTGTGGGGAAATTCGAAACCTACAAGCGCGTGAAGTGGTGTTGGGATATGAATTACCTGAAGCAGAGCACCAAGTGTT
GGCAAATCAAATGAATTTGTTATTATCACAGGTGGAAACTGCTTTTGAAGATGTTCAGCTATTAGGAGATGATTTGTCTC
GCCTAGAATATCAAGTAGCTGGGAAACTGTTAGAATATGTTCACCAGACGCAGCTGCGTGAGCTTAGTCACTTAAAGCAA
GTTCATCATTATGAAATTAAAGATTTCTTACAGATGGACTATGCAACTATGACAAGTCTAGATTTAACAGAGAATGCACG
GACGGGGAAGAAGCATGGCAGTCTTTATTGGTTGATGGACGAGACCAAGACAGCTATGGGGACGCGACTTCTAAGAAGAT
GGATCCAGCATCCGTTGCTTGATAAGGAACGGATTCTTAAGCGGCAGGATGTCGTACAAGTCTTTTTAGATCATTTTTTT
GAGCGTAGTGATTTGGCAGATAGTCTCAAAGGGGTTTATGATATTGAGCGCTTGGCAAGCCGTGTTTCTTTTGGGAAGAC
AAACCCGAAGGATTTATTGCAGTTGGCGGCAACATTGAGCAATGTCCCTCAGATTAAGGGAATTTTACAAGGAATCGATC
ATCCTGTTTTGGGACAGTTGATTGAAAACTTGGATGATATTCCAGAATTGGCAAACTTGATTCAGTCGGCAATTTCTCCT
GATGCTCCAAATGTTATTACGGAAGGGAATATCATTCAAACTGGTTTTGATGAAACCTTAGATAAGTATCGAGTGGTTCT
GCGAGATGGTACGAGCTGGATTGCTGATATTGAAGCGAAAGAAAGGGTGGCTAGTGGGATTAATAATCTAAAAATTGATT
ACAATAAAAAAGACGGTTATTATTTCCATGTTACTAATTCACAGTTGGAGCACGTACCTAGCCACTTTTTCCGAAAAGCA
ACGTTGAAAAATTCAGAACGATTTGGTACAGAGGAATTGGCTCGTATTGAAGGCGAAATGTTGGAAGCGCGTGAAAAATC
GGCCAATTTAGAGTATGAGATTTTTATACGTATTCGGGAAGAAGCTGGTAAATATATCAAACGATTACAATCCTTGGCAC
AAACTCTAGCAACAGTGGATGTATTGCAGAGTTTTGCAGCAGTTGCTGAAAAGCAACGCTTTGTACGCCCAGAATTTATT
GAACGTCCTTCCATTGAAATCGATAAGGGACGGCATGCAGTTGTAGAAAAGGTTATGGGTGCACAAACTTATATTCCGAA
TAGTATTTCAATGGATGAGAATGTCAATCTTCAGTTAATTACAGGTCCAAATATGAGTGGGAAGTCAACCTATATGCGGC
AATTAGCGATTATTGTTATCATGGCGCAAATGGGTTCCTATGTTTCAGCTGAGAGTGCTCAATTACCAATTTTTGATGCC
ATCTTCACTCGAATTGGTGCGGCAGATGACTTGGTATCTGGACAATCAACCTTTATGGTAGAAATGATGGAAGCAAATCA
TGCTATTTCTCAAGCGACTGAACACTCTCTTATTCTTTTTGATGAGTTGGGGAGAGGGACAGCAACATATGATGGGATGG
CTCTTGCTCAGGCAATTATTGAATATATCCACAATCGAACAGGAGCAAAGACCCTTTTTGCTACACACTATCATGAGTTG
ACAGACTTGTCAACTAGCTTGACACAGTTAGAAAATGTTCATGTGGCAACTTTAGAAAAAGATGGGAAAGTGACTTTTCT
TCATAAGATTGAAGCTGGTCCTGCAGATAAATCTTATGGGATTCATGTCGCAAGAATTGCAGGTTTACCAAATGATTTGT
TGATGAGAGCCGACCAGATACTAGCAAGACTAGAAGAACAAGCAAATGAGAAACCATCTCTCAATCCTTCTAATAAAGGA
GCTAATGATAGTAAGGAAAATCAAGTATCTGAGCAGATATCTTTATTCACAGAAACAACTGAATCACCTATTTTAGATGA
ACTACGTCAGTTGGATATTTATAATATGACCCCAATGGAAGTGATGCTAGCTATAGCTGAGATGAAAAAACATCTCTGA

Domains

Predicted by InterProScan.

• MutS domain III (MutS_III) (255-546)

• MutS domain V (MutS_V) (599-785)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain II (MutS_II) (126-239)

• MutS domain I (MutS_I) (8-118)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	75.469	100	0.755
mutS	Pseudomonas stutzeri strain ATCC 17587	36.311	100	0.367