Detailed information    

insolico Bioinformatically predicted

Overview

Name   brsR   Type   Regulator
Locus tag   R8522_RS00960 Genome accession   NZ_AP026916
Coordinates   174308..174748 (-) Length   146 a.a.
NCBI ID   WP_000861973.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700006     
Function   antagonizing the proteolysis of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 169308..179748
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8522_RS00935 (PC0006_01870) - 169660..170193 (+) 534 WP_000729030.1 hypothetical protein -
  R8522_RS00940 (PC0006_01880) nrdI 170271..170741 (+) 471 WP_000849621.1 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI -
  R8522_RS00945 (PC0006_01890) - 171034..172296 (-) 1263 WP_000075789.1 NRAMP family divalent metal transporter -
  R8522_RS00950 (PC0006_01900) - 172439..173392 (-) 954 WP_001155321.1 IS30-like element ISSpn8 family transposase -
  R8522_RS00955 (PC0006_01910) - 173853..174311 (-) 459 WP_000745059.1 DUF3021 domain-containing protein -
  R8522_RS00960 (PC0006_01920) brsR 174308..174748 (-) 441 WP_000861973.1 LytTR family DNA-binding domain-containing protein Regulator
  R8522_RS00965 - 174836..174961 (-) 126 WP_001813544.1 hypothetical protein -
  R8522_RS00970 (PC0006_01930) hexB 175104..177053 (+) 1950 WP_000018178.1 DNA mismatch repair endonuclease MutL Machinery gene
  R8522_RS00975 (PC0006_01940) ribE 177378..177845 (-) 468 WP_001099502.1 6,7-dimethyl-8-ribityllumazine synthase -
  R8522_RS00980 (PC0006_01950) - 177846..179051 (-) 1206 WP_000456641.1 bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II -
  R8522_RS00985 (PC0006_01960) ribE 179071..179706 (-) 636 WP_000493843.1 riboflavin synthase -

Sequence

Protein


Download         Length: 146 a.a.        Molecular weight: 17151.84 Da        Isoelectric Point: 5.9842

>NTDB_id=81558 R8522_RS00960 WP_000861973.1 174308..174748(-) (brsR) [Streptococcus pneumoniae strain PZ900700006]
MKVELQISETYEEEKLIVQAPQPTEKVQKVIEFAENLDQREKIKGKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSI
DLRLYQVLKLLPTNFIQISQSEIINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL

Nucleotide


Download         Length: 441 bp        

>NTDB_id=81558 R8522_RS00960 WP_000861973.1 174308..174748(-) (brsR) [Streptococcus pneumoniae strain PZ900700006]
ATGAAAGTAGAACTACAGATTAGTGAGACTTACGAGGAGGAAAAGCTGATTGTCCAAGCACCTCAGCCGACAGAAAAAGT
CCAGAAAGTCATCGAGTTCGCAGAAAATCTGGACCAAAGAGAAAAAATCAAAGGAAAAATCGATGATCAGGTCTATCTAG
TTGAGATTGGCAAGATTCAGCGCTTCTATATCGAGAATCGGAAGGTTCTAGCAGAAACCGCGAGTCAGACCTACAGCATT
GATTTGCGACTCTATCAGGTTCTTAAACTCTTGCCAACCAATTTTATCCAAATTTCCCAATCAGAAATCATCAATATCGA
TTCCATCTCTCACCTCAAGCTCACGCCAAACGGTCTGGTAGAAATTTTCTTGAAAAACGAAAGCTTCACCTACTCTTCAC
GCCGTTATCTAAAAACCATCAAGGAGAAATTAGAACTATGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(50-144)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  brsR Streptococcus mutans UA159

36.054

100

0.363

Multiple sequence alignment