Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   PA12_RS25365 Genome accession   NZ_CP136598
Coordinates   5412629..5413843 (-) Length   404 a.a.
NCBI ID   WP_003112721.1    Uniprot ID   Q9I5N8
Organism   Pseudomonas aeruginosa strain PA12     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 5407629..5418843
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PA12_RS25360 (PA12_gene4946) - 5410938..5412116 (-) 1179 WP_023116094.1 substrate-binding domain-containing protein -
  PA12_RS25365 (PA12_gene4947) pilC 5412629..5413843 (-) 1215 WP_003112721.1 type II secretion system inner membrane protein GspF Machinery gene
  PA12_RS25370 (PA12_gene4948) pilB 5413843..5415252 (-) 1410 WP_003120811.1 type II secretion system ATPase GspE Machinery gene
  PA12_RS25375 (PA12_gene4949) gspD 5415249..5417660 (-) 2412 WP_191519327.1 type II secretion system secretin GspD -
  PA12_RS25380 (PA12_gene4950) - 5417657..5418250 (-) 594 WP_023096963.1 type II secretion system protein M -

Sequence

Protein


Download         Length: 404 a.a.        Molecular weight: 43409.42 Da        Isoelectric Point: 9.3769

>NTDB_id=815214 PA12_RS25365 WP_003112721.1 5412629..5413843(-) (pilC) [Pseudomonas aeruginosa strain PA12]
MQTFRYEAADAQGRIETGTLEADSQRGALGQLRARGLTPLEVREQAGGGTGQGAGALFAPRLSDGDLAWATRQLASLLAA
SLPLEAALSATLDQAERKHIAQTLSAVRSDVRGGMRLADALAARPRDFPEIYRALVAAGEESGDLAQVMERLADYIEERN
ALRGKILTAFIYPAVVGVVSIGIVIFLLGYVVPQVVSAFSQARQDLPALTRAMLQASDFVRAWGWLCAGAIGSAYWGWRL
YLRDPQARLGWHRRVLRLPLLGRFVLGVNTARFASTLAILGSAGVPLLRALDAARQTLANDCLAQAVEEATAQVREGVSL
ASALRTRQVFPPILTHLIASGEKTGALPPMLDRAAQTLSRDIERRAMGMTALLEPLMIVVMGGVVLTIVMAVLMPIIEMN
QLVQ

Nucleotide


Download         Length: 1215 bp        

>NTDB_id=815214 PA12_RS25365 WP_003112721.1 5412629..5413843(-) (pilC) [Pseudomonas aeruginosa strain PA12]
ATGCAGACCTTCCGTTACGAAGCCGCCGACGCCCAGGGCCGGATCGAGACCGGCACCCTGGAGGCGGACAGCCAGCGTGG
CGCCCTCGGCCAACTGCGCGCCCGCGGCCTGACCCCGCTGGAGGTCCGCGAGCAGGCTGGCGGCGGGACCGGGCAAGGGG
CGGGCGCGCTGTTCGCCCCGCGCCTGTCCGACGGCGACCTGGCCTGGGCCACCCGCCAGCTGGCCAGCCTGCTGGCCGCC
AGCCTGCCGCTGGAGGCGGCGCTGAGCGCCACCCTCGACCAGGCCGAGCGCAAGCACATCGCCCAGACCCTGAGCGCCGT
GCGCAGCGACGTACGCGGCGGCATGCGCCTGGCCGACGCCCTTGCCGCACGGCCGCGGGACTTCCCGGAAATCTACCGGG
CGCTGGTGGCTGCGGGCGAGGAGTCCGGCGACCTGGCCCAGGTGATGGAGCGCCTGGCCGACTACATCGAGGAACGCAAC
GCCCTGCGCGGCAAGATCCTCACCGCGTTCATCTACCCGGCGGTGGTCGGCGTGGTCTCCATCGGCATCGTCATTTTCCT
CCTCGGCTACGTGGTGCCGCAGGTGGTCAGCGCCTTCTCCCAGGCGCGCCAGGACCTGCCGGCGCTGACCCGGGCGATGC
TCCAGGCCAGCGACTTCGTGCGCGCCTGGGGCTGGCTCTGCGCCGGCGCCATCGGTAGCGCTTACTGGGGCTGGCGCTTG
TACCTGCGCGACCCGCAGGCGCGGCTCGGCTGGCACCGGCGAGTGCTGCGCCTGCCTCTGCTCGGTCGTTTCGTGCTCGG
GGTGAATACCGCGCGCTTCGCCTCCACCCTGGCGATCCTCGGCAGCGCTGGCGTACCGCTGCTGCGCGCGCTCGATGCGG
CGCGCCAGACGTTGGCCAACGACTGCCTCGCGCAGGCGGTGGAGGAGGCCACCGCGCAGGTTCGCGAAGGTGTCTCGCTG
GCCTCGGCGCTGCGCACGCGGCAGGTGTTCCCGCCGATCCTCACCCACCTGATCGCCAGCGGCGAGAAGACCGGTGCGCT
GCCGCCGATGCTCGACCGCGCAGCGCAGACCCTGTCGCGCGACATCGAGCGCCGCGCCATGGGCATGACCGCGTTGCTCG
AGCCGCTGATGATCGTGGTCATGGGCGGGGTGGTGCTGACCATCGTGATGGCGGTGCTGATGCCGATCATCGAGATGAAC
CAACTGGTCCAGTAG

Domains

Predicted by InterProScan.

Type II secretion system (T2SS), protein F (T2SSF)

(273-395)

Type II secretion system (T2SS), protein F (T2SSF)

(71-193)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9I5N8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Thermus thermophilus HB27

36.386

100

0.364