Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilH   Type   Machinery gene
Locus tag   PA12_RS02280 Genome accession   NZ_CP136598
Coordinates   485737..486102 (+) Length   121 a.a.
NCBI ID   WP_003084587.1    Uniprot ID   A0A0H2ZKW2
Organism   Pseudomonas aeruginosa strain PA12     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 480737..491102
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PA12_RS02250 (PA12_gene444) pyrR 481359..481871 (-) 513 WP_003084574.1 bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase PyrR -
  PA12_RS02255 (PA12_gene445) ruvX 481983..482417 (-) 435 WP_003084575.1 Holliday junction resolvase RuvX -
  PA12_RS02260 (PA12_gene446) - 482417..482986 (-) 570 WP_003084577.1 YqgE/AlgH family protein -
  PA12_RS02265 (PA12_gene447) - 483035..483928 (-) 894 WP_003162015.1 energy transducer TonB -
  PA12_RS02270 (PA12_gene448) gshB 484075..485028 (-) 954 WP_003100943.1 glutathione synthase -
  PA12_RS02275 (PA12_gene449) pilG 485283..485690 (+) 408 WP_003084583.1 twitching motility response regulator PilG Regulator
  PA12_RS02280 (PA12_gene450) pilH 485737..486102 (+) 366 WP_003084587.1 twitching motility response regulator PilH Machinery gene
  PA12_RS02285 (PA12_gene451) - 486153..486689 (+) 537 WP_003084590.1 chemotaxis protein CheW -
  PA12_RS02290 (PA12_gene452) pilJ 486774..488822 (+) 2049 WP_003100940.1 chemotaxis chemoreceptor PilJ -
  PA12_RS02295 (PA12_gene453) pilK 488883..489758 (+) 876 WP_031757002.1 type 4 fimbrial methyltransferase PilK -

Sequence

Protein


Download         Length: 121 a.a.        Molecular weight: 13273.30 Da        Isoelectric Point: 5.1961

>NTDB_id=815162 PA12_RS02280 WP_003084587.1 485737..486102(+) (pilH) [Pseudomonas aeruginosa strain PA12]
MARILIVDDSPTEMYKLTAMLEKHGHQVLKAENGGDGVALARQEKPDVVLMDIVMPGLNGFQATRQLTKDAETSAIPVII
VTTKDQETDKVWGKRQGARDYLTKPVDEETLLKTINAVLAG

Nucleotide


Download         Length: 366 bp        

>NTDB_id=815162 PA12_RS02280 WP_003084587.1 485737..486102(+) (pilH) [Pseudomonas aeruginosa strain PA12]
ATGGCTCGTATTTTGATTGTTGATGACTCTCCGACCGAGATGTACAAGCTGACCGCCATGCTGGAAAAGCATGGTCACCA
GGTACTCAAGGCCGAGAACGGCGGCGACGGCGTCGCCCTGGCCCGCCAGGAAAAGCCCGACGTGGTCCTGATGGACATCG
TCATGCCCGGCCTCAACGGCTTCCAGGCGACCCGTCAATTGACCAAGGACGCCGAGACCAGCGCCATCCCGGTGATCATC
GTCACCACCAAGGACCAGGAGACCGACAAGGTCTGGGGCAAGCGCCAGGGCGCTCGCGACTACCTGACCAAGCCGGTGGA
CGAAGAGACCCTGCTGAAAACCATCAATGCGGTGCTGGCGGGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2ZKW2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilH Synechocystis sp. PCC 6803

36.975

98.347

0.364