Detailed information NTG0813765

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: QBE57_RS00680
• Genome accession: NZ_CP121670
• Coordinates: 135644..136693 (+)
• Length: 349 a.a.
• NCBI ID: WP_012775295.1
• Uniprot ID: A0A2K1T047
• Organism: Streptococcus suis strain HBXY-SL
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 130644..141693

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QBE57_RS00645	-	130948..132042 (+)	1095	WP_012027602.1	sensor histidine kinase	-
QBE57_RS00650	-	132039..132641 (+)	603	WP_012027601.1	response regulator transcription factor	-
QBE57_RS00655	-	132949..133167 (+)	219	WP_004194736.1	YqgQ family protein	-
QBE57_RS00660	-	133167..133553 (+)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
QBE57_RS00665	-	133610..134332 (+)	723	WP_012027598.1	lipoprotein	-
QBE57_RS00670	rsmD	134640..135179 (+)	540	WP_009910569.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
QBE57_RS00675	coaD	135169..135657 (+)	489	WP_012027597.1	pantetheine-phosphate adenylyltransferase	-
QBE57_RS00680	sepM	135644..136693 (+)	1050	WP_012775295.1	SepM family pheromone-processing serine protease	Regulator
QBE57_RS00685	-	136881..137522 (+)	642	WP_012027595.1	YutD family protein	-
QBE57_RS00690	rlmN	137531..138643 (+)	1113	WP_012028433.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
QBE57_RS00695	-	138640..139167 (+)	528	WP_012027591.1	VanZ family protein	-
QBE57_RS00700	nadE	140463..141287 (-)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37761.83 Da
• Isoelectric Point: 4.6112

>NTDB_id=813765 QBE57_RS00680 WP_012775295.1 135644..136693(+) (sepM) [Streptococcus suis strain HBXY-SL]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=813765 QBE57_RS00680 WP_012775295.1 135644..136693(+) (sepM) [Streptococcus suis strain HBXY-SL]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAGGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAGACATCGCAAAATATGGCGAAGTACCAAGGTTTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGGATAGGTATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACAGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAATCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACAAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A2K1T047

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605