Detailed information NTG0812889

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: QA712_RS10620
• Genome accession: NZ_CP121539
• Coordinates: 1980092..1982542 (+)
• Length: 816 a.a.
• NCBI ID: WP_372757131.1
• Uniprot ID: -
• Organism: Lactococcus lactis strain MA5
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1975092..1987542

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QA712_RS10595 (QA712_10595)	-	1975856..1976368 (+)	513	WP_012897343.1	adenine phosphoribosyltransferase	-
QA712_RS10600 (QA712_10600)	rpoE	1976585..1977148 (+)	564	WP_047205762.1	DNA-directed RNA polymerase subunit delta	-
QA712_RS10605 (QA712_10605)	mltG	1977285..1978937 (+)	1653	WP_047205763.1	endolytic transglycosylase MltG	-
QA712_RS10610 (QA712_10610)	greA	1978997..1979470 (+)	474	WP_025016857.1	transcription elongation factor GreA	-
QA712_RS10615 (QA712_10615)	-	1979647..1980102 (+)	456	WP_010905471.1	CtsR family transcriptional regulator	-
QA712_RS10620 (QA712_10620)	clpC	1980092..1982542 (+)	2451	WP_372757131.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
QA712_RS10625 (QA712_10625)	hpf	1982677..1983234 (+)	558	WP_003129564.1	ribosome hibernation-promoting factor, HPF/YfiA family	-
QA712_RS10630 (QA712_10630)	eno	1983422..1984723 (+)	1302	WP_010905473.1	surface-displayed alpha-enolase	-
QA712_RS10635 (QA712_10635)	-	1984838..1985509 (-)	672	WP_015425956.1	ABC transporter ATP-binding protein	-
QA712_RS10640 (QA712_10640)	-	1985512..1986585 (-)	1074	WP_017864217.1	ABC transporter permease	-
QA712_RS10645 (QA712_10645)	-	1986597..1987166 (-)	570	WP_372757134.1	TetR/AcrR family transcriptional regulator	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 90473.95 Da
• Isoelectric Point: 6.8034

>NTDB_id=812889 QA712_RS10620 WP_372757131.1 1980092..1982542(+) (clpC) [Lactococcus lactis strain MA5]
MKFENIKYTPTLDRILEKAEEYAHQYQYGTIESAHLLAAMATTSGSIAYSLLAGMNVDSSDLLIDLEDLSSHVKVKRSTL
RFSPRAEEVMTAASFLAIHNNSEAVGTEHLLYALLQVEDGFGLQLLKLQKINIVSLRKELEKRTGLKVPESKKAVTPMSK
RKMAKGVAENSTTPTLDSVSSDLTEEARLGKLDPMIGREAEIDRLIHILSRRTKNNPVLVGEPGVGKSAIIEGLAQRIVN
GQVPIGLMNSRIMALNMATVVAGTKFRGEFEDRLTAIVEEVSSDPDVIIFIDELHTIIGAGGGMDSVNDAANILKPALAR
GDFQMVGATTYHEYQKYIEKDEALERRLARINVDEPSPDEAIAILQGLREKFEDYHQVKFTDQAIKSAVMLSVRYMTSRK
LPDKAIDLLDEAAAAVKISVKNQQTKRLDLEKELAKAQEELSEAVIKLDIKASRTKEKAVEKIADKIYKFSVKEDKRQEV
TDQAVVTVASTLTGVPITQMTKSESDRLINLEKELHKRVVGQEEAISAVSRAIRRARSGVADSRRPMGSFMFLGPTGVGK
TELAKALADSVFGSEDNMIRVDMSEFMEKHSTSRLIGAPPGYVGYDEGGQLTERVRNKPYSVVLLDEVEKAHPDVFNIML
QILDDGFVTDTKGRKVDFRNTIIIMTSNLGATALRDDKTVGFGAKNITADYSAMKSRILEELKRHYRPEFLNRIDENIVF
HSLESQEIEQIVKIMSKSLIKRLAEQDIHVKLTPSAVKLIAEVGFDPEYGARPLRKALQKEVEDLLSEQLLSGEIKAGNR
VSIGASNKKIKIAQIV

Nucleotide

• Length: 2451 bp

>NTDB_id=812889 QA712_RS10620 WP_372757131.1 1980092..1982542(+) (clpC) [Lactococcus lactis strain MA5]
ATGAAATTTGAAAATATAAAATATACACCAACGCTTGACCGAATTTTAGAAAAAGCGGAAGAGTATGCTCACCAATATCA
ATATGGCACTATTGAAAGTGCTCATTTACTGGCTGCAATGGCAACGACCTCAGGCTCAATTGCTTACAGCCTTCTTGCAG
GAATGAATGTTGATTCTTCTGACTTACTGATTGATTTAGAGGATTTATCAAGTCATGTTAAGGTCAAACGTTCAACTTTA
CGTTTTTCACCTCGTGCAGAAGAAGTGATGACTGCGGCAAGTTTTTTAGCAATTCATAATAACTCCGAAGCCGTTGGAAC
AGAACACTTGCTTTATGCCCTACTTCAAGTAGAAGATGGATTTGGTCTTCAACTTCTGAAATTACAAAAAATCAATATTG
TATCTTTGCGAAAAGAGCTTGAGAAAAGAACTGGACTCAAAGTTCCAGAAAGTAAAAAAGCTGTGACTCCAATGTCAAAG
CGTAAGATGGCAAAGGGAGTTGCAGAAAATTCAACGACGCCAACGTTAGACTCTGTATCCTCAGATTTAACCGAAGAAGC
TCGCTTGGGTAAACTTGACCCAATGATTGGACGAGAAGCTGAAATTGACCGTTTGATTCATATTCTCAGCCGCAGAACAA
AAAATAATCCTGTCTTAGTTGGAGAGCCCGGTGTTGGGAAATCAGCAATTATTGAAGGTTTGGCCCAAAGAATTGTCAAT
GGTCAAGTTCCAATTGGTTTGATGAATAGTCGAATTATGGCCTTGAATATGGCGACTGTTGTTGCTGGGACAAAATTTAG
AGGTGAATTTGAGGATCGTTTGACAGCTATTGTTGAAGAAGTTAGCAGTGATCCAGATGTCATTATTTTCATTGATGAAT
TACACACAATCATTGGTGCTGGTGGCGGTATGGATTCTGTCAATGATGCCGCAAATATTTTGAAACCAGCGCTTGCTCGT
GGTGATTTTCAAATGGTCGGAGCAACAACCTATCATGAATATCAAAAATATATTGAAAAGGATGAAGCTTTAGAACGCCG
TTTGGCGAGAATAAATGTTGATGAGCCAAGTCCAGATGAAGCGATTGCTATTTTGCAAGGCTTACGTGAAAAATTTGAAG
ACTATCATCAAGTGAAATTTACTGACCAAGCCATTAAAAGTGCTGTAATGCTCAGTGTTCGCTATATGACTAGCCGAAAA
TTGCCTGACAAAGCCATTGATTTACTTGATGAAGCTGCAGCAGCAGTGAAAATTTCTGTCAAAAATCAACAAACAAAACG
TCTTGATTTAGAAAAAGAATTAGCCAAAGCTCAAGAAGAATTATCAGAAGCTGTCATTAAACTTGATATCAAAGCGTCTC
GTACAAAAGAAAAAGCAGTTGAAAAAATTGCTGACAAGATTTATAAATTCTCAGTAAAAGAAGATAAACGTCAAGAAGTT
ACTGATCAAGCTGTTGTTACTGTTGCCTCAACACTGACAGGTGTTCCAATCACACAAATGACTAAGTCTGAAAGTGATCG
TTTAATCAATCTTGAAAAAGAATTACACAAACGAGTTGTTGGACAAGAAGAAGCTATTTCTGCCGTTTCAAGAGCCATTC
GTCGGGCACGTTCCGGTGTTGCTGACAGCCGCCGTCCAATGGGTTCTTTCATGTTCCTTGGACCAACAGGGGTCGGTAAA
ACCGAACTTGCTAAAGCACTGGCTGACAGTGTGTTTGGTAGTGAAGATAATATGATTCGTGTTGACATGAGTGAATTCAT
GGAAAAACATTCAACTTCACGCTTGATTGGGGCTCCTCCAGGGTATGTAGGTTATGATGAGGGTGGTCAATTGACAGAAC
GCGTTCGTAATAAACCTTATTCTGTTGTTCTTTTAGATGAAGTCGAAAAAGCTCATCCTGACGTTTTCAACATCATGTTG
CAAATTCTAGATGATGGCTTTGTGACTGATACTAAAGGTCGCAAAGTTGATTTCAGAAATACAATTATTATAATGACTTC
AAACTTGGGAGCGACTGCTCTTCGTGATGATAAGACAGTTGGTTTTGGCGCTAAAAATATCACAGCTGATTATTCAGCCA
TGAAATCAAGAATTTTAGAAGAGCTTAAACGTCATTATCGCCCTGAGTTTCTTAATCGAATTGATGAAAATATTGTTTTC
CATTCATTGGAAAGTCAAGAGATTGAACAAATTGTTAAAATTATGAGTAAATCTTTGATTAAACGTCTGGCAGAACAAGA
TATTCATGTTAAACTCACGCCGTCAGCGGTGAAACTAATTGCTGAGGTAGGTTTTGACCCAGAATATGGTGCACGTCCGC
TTCGTAAGGCACTTCAAAAAGAAGTCGAAGACCTTTTAAGTGAACAATTGCTCTCTGGTGAAATCAAAGCAGGGAATCGT
GTTTCAATTGGTGCATCTAATAAAAAAATTAAAATCGCTCAAATTGTTTGA

Domains

Predicted by InterproScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (19-69)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (96-144)

• AAA domain (Cdc48 subfamily) (AAA_2) (545-716)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (723-802)

• AAA lid domain (AAA_lid_9) (357-453)

• ATPase family associated with various cellular activities (AAA) (AAA) (218-334)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	99.632	100	0.996
clpC	Streptococcus thermophilus LMG 18311	50.662	100	0.516
clpC	Streptococcus thermophilus LMD-9	50.542	100	0.515
clpC	Streptococcus pneumoniae Rx1	48.854	100	0.496
clpC	Streptococcus pneumoniae D39	48.854	100	0.496
clpC	Streptococcus pneumoniae TIGR4	48.733	100	0.495
clpC	Bacillus subtilis subsp. subtilis str. 168	50.249	98.284	0.494
clpC	Streptococcus mutans UA159	48.317	100	0.493
clpC	Lactococcus lactis subsp. cremoris KW2	47.328	80.27	0.38
clpE	Streptococcus mutans UA159	47.692	79.657	0.38
clpE	Streptococcus pneumoniae TIGR4	47.528	76.838	0.365
clpE	Streptococcus pneumoniae Rx1	47.528	76.838	0.365
clpE	Streptococcus pneumoniae D39	47.528	76.838	0.365
clpE	Streptococcus pneumoniae R6	47.528	76.838	0.365