Detailed information NTG0812765

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: QA624_RS08175
• Genome accession: NZ_CP121526
• Coordinates: 1375482..1376528 (-)
• Length: 348 a.a.
• NCBI ID: WP_001830374.1
• Uniprot ID: A0A0N1EGU4
• Organism: Staphylococcus epidermidis strain 1FSE05
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1370482..1381528

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QA624_RS08145	-	1370866..1372107 (-)	1242	WP_002457094.1	aminopeptidase	-
QA624_RS08150	-	1372109..1372324 (-)	216	WP_001830421.1	DUF1128 domain-containing protein	-
QA624_RS08155	-	1372465..1372929 (+)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
QA624_RS08160	-	1372937..1373221 (+)	285	WP_001830401.1	YtxH domain-containing protein	-
QA624_RS08165	-	1373628..1374806 (+)	1179	WP_001830411.1	YihY/virulence factor BrkB family protein	-
QA624_RS08170	vraR	1374863..1375492 (-)	630	WP_001830439.1	two-component system response regulator VraR	Regulator
QA624_RS08175	vraS	1375482..1376528 (-)	1047	WP_001830374.1	sensor histidine kinase	Regulator
QA624_RS08180	liaF	1376525..1377226 (-)	702	WP_002457093.1	cell wall-active antibiotics response protein LiaF	-
QA624_RS08185	-	1377241..1377627 (-)	387	WP_001830382.1	hypothetical protein	-
QA624_RS08190	map	1377785..1378540 (-)	756	WP_002457092.1	type I methionyl aminopeptidase	-
QA624_RS08195	-	1378714..1379700 (+)	987	WP_002457091.1	aromatic acid exporter family protein	-
QA624_RS08200	-	1379851..1380387 (-)	537	WP_001830372.1	hypothetical protein	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40066.49 Da
• Isoelectric Point: 5.8512

>NTDB_id=812765 QA624_RS08175 WP_001830374.1 1375482..1376528(-) (vraS) [Staphylococcus epidermidis strain 1FSE05]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLLIVLLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=812765 QA624_RS08175 WP_001830374.1 1375482..1376528(-) (vraS) [Staphylococcus epidermidis strain 1FSE05]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAATATTATCTTTTTTCAGGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATTGTTCTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCA
CAAATAGAAAGATCAATAGAAGGACAAACAGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAAAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAACGACTTGCCAGGGAATTACATGATTCTGTTAGT
CAACAATTATTTGCTGCGAGCATGATGCTATCGGCGATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTATTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTTTAGGTGAAGGAATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTGTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGCATTGAAGATCACTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACAAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GATTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTGAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0N1EGU4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	93.023	98.851	0.92