Detailed information NTG0812706

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: QA594_RS11560
• Genome accession: NZ_CP121518
• Coordinates: 2413333..2414379 (-)
• Length: 348 a.a.
• NCBI ID: WP_001830374.1
• Uniprot ID: A0A0N1EGU4
• Organism: Staphylococcus epidermidis strain 6DSE07
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2408333..2419379

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QA594_RS11530	-	2408696..2409937 (-)	1242	WP_002503582.1	aminopeptidase	-
QA594_RS11535	-	2409939..2410154 (-)	216	WP_070501292.1	DUF1128 domain-containing protein	-
QA594_RS11540	-	2410295..2410759 (+)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
QA594_RS11545	-	2410767..2411051 (+)	285	WP_001830401.1	YtxH domain-containing protein	-
QA594_RS11550	-	2411479..2412657 (+)	1179	WP_049376906.1	YihY/virulence factor BrkB family protein	-
QA594_RS11555	vraR	2412714..2413343 (-)	630	WP_001830439.1	two-component system response regulator VraR	Regulator
QA594_RS11560	vraS	2413333..2414379 (-)	1047	WP_001830374.1	sensor histidine kinase	Regulator
QA594_RS11565	liaF	2414376..2415077 (-)	702	WP_002457093.1	cell wall-active antibiotics response protein LiaF	-
QA594_RS11570	-	2415092..2415478 (-)	387	WP_001830382.1	hypothetical protein	-
QA594_RS11575	map	2415636..2416391 (-)	756	WP_002457092.1	type I methionyl aminopeptidase	-
QA594_RS11580	-	2416565..2417551 (+)	987	WP_002457091.1	aromatic acid exporter family protein	-
QA594_RS11585	-	2417701..2418237 (-)	537	WP_001830372.1	hypothetical protein	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40066.49 Da
• Isoelectric Point: 5.8512

>NTDB_id=812706 QA594_RS11560 WP_001830374.1 2413333..2414379(-) (vraS) [Staphylococcus epidermidis strain 6DSE07]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLLIVLLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=812706 QA594_RS11560 WP_001830374.1 2413333..2414379(-) (vraS) [Staphylococcus epidermidis strain 6DSE07]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAATATTATCTTTTTTCAGGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATTGTTCTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCA
CAAATAGAAAGATCAATAGAAGGACAAACAGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAAAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAACGACTTGCCAGGGAATTACATGATTCTGTTAGT
CAACAATTATTTGCTGCGAGCATGATGCTATCGGCGATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTATTACATTTAAGGCCGATAGGTTTAAAAG
ATAAGTCTTTAGGTGAAGGAATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTGTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGCATTGAAGATCACTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACAAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GGTTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTGAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0N1EGU4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	93.023	98.851	0.92