Detailed information NTG0812631

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: QA595_RS08260
• Genome accession: NZ_CP121509
• Coordinates: 1775472..1776518 (-)
• Length: 348 a.a.
• NCBI ID: WP_001830374.1
• Uniprot ID: A0A0N1EGU4
• Organism: Staphylococcus epidermidis strain 21FSE01
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1770472..1781518

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QA595_RS08230	-	1770856..1772097 (-)	1242	WP_001832467.1	aminopeptidase	-
QA595_RS08235	-	1772099..1772314 (-)	216	WP_001830421.1	DUF1128 domain-containing protein	-
QA595_RS08240	-	1772455..1772919 (+)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
QA595_RS08245	-	1772927..1773211 (+)	285	WP_001830401.1	YtxH domain-containing protein	-
QA595_RS08250	-	1773618..1774796 (+)	1179	WP_002485151.1	YihY/virulence factor BrkB family protein	-
QA595_RS08255	vraR	1774853..1775482 (-)	630	WP_001830439.1	two-component system response regulator VraR	Regulator
QA595_RS08260	vraS	1775472..1776518 (-)	1047	WP_001830374.1	sensor histidine kinase	Regulator
QA595_RS08265	liaF	1776515..1777216 (-)	702	WP_002457093.1	cell wall-active antibiotics response protein LiaF	-
QA595_RS08270	-	1777231..1777617 (-)	387	WP_001830382.1	hypothetical protein	-
QA595_RS08275	map	1777775..1778530 (-)	756	WP_002457092.1	type I methionyl aminopeptidase	-
QA595_RS08280	-	1778704..1779690 (+)	987	WP_001830388.1	aromatic acid exporter family protein	-
QA595_RS08285	-	1779841..1780377 (-)	537	WP_278276335.1	hypothetical protein	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40066.49 Da
• Isoelectric Point: 5.8512

>NTDB_id=812631 QA595_RS08260 WP_001830374.1 1775472..1776518(-) (vraS) [Staphylococcus epidermidis strain 21FSE01]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLLIVLLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=812631 QA595_RS08260 WP_001830374.1 1775472..1776518(-) (vraS) [Staphylococcus epidermidis strain 21FSE01]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAATATTATCTTTTTTCAGGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATTGTTCTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCA
CAAATAGAAAGATCAATAGAAGGACAAACAGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAAAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAACGACTTGCCAGGGAATTACATGATTCTGTTAGT
CAACAATTATTTGCTGCGAGCATGATGCTATCGGCGATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTATTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTTTAGGTGAAGGAATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTGTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGCATTGAAGATCACTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACAAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GGTTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTGAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0N1EGU4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	93.023	98.851	0.92