Detailed information NTG0812249

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: P8P68_RS07380
• Genome accession: NZ_CP121467
• Coordinates: 1510077..1512509 (+)
• Length: 810 a.a.
• NCBI ID: WP_278275838.1
• Uniprot ID: A0AAX3THH2
• Organism: Streptococcus sp. D7B5
• Function: degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 1505077..1517509

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P8P68_RS07370 (P8P68_07370)	-	1505687..1509445 (+)	3759	WP_278276308.1	FctA domain-containing protein	-
P8P68_RS07375 (P8P68_07375)	-	1509617..1510075 (+)	459	WP_001211258.1	CtsR family transcriptional regulator	-
P8P68_RS07380 (P8P68_07380)	clpC	1510077..1512509 (+)	2433	WP_278275838.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
P8P68_RS07385 (P8P68_07385)	-	1512655..1513713 (+)	1059	WP_278275839.1	AAA family ATPase	-
P8P68_RS07390 (P8P68_07390)	pnuC	1513723..1514502 (+)	780	WP_268710390.1	nicotinamide riboside transporter PnuC	-
P8P68_RS07395 (P8P68_07395)	-	1514504..1515277 (+)	774	WP_061428116.1	NUDIX hydrolase	-
P8P68_RS07400 (P8P68_07400)	-	1515327..1515557 (-)	231	WP_278275840.1	hypothetical protein	-
P8P68_RS07405 (P8P68_07405)	-	1515821..1516504 (+)	684	WP_278275841.1	hypothetical protein	-

Sequence

Protein

• Length: 810 a.a.
• Molecular weight: 90302.21 Da
• Isoelectric Point: 6.2768

>NTDB_id=812249 P8P68_RS07380 WP_278275838.1 1510077..1512509(+) (clpC) [Streptococcus sp. D7B5]
MNYSKALNECIESAYMVASHFGAHYLESWHLLIAMSNHSYSVAGATLNDYPYEMDRLEEVALELTETDYSQDETFTELPF
SHRLEVLFAEAEYVASVVHAKVLGTEHVLYAILHDGNALATRILERAGFSYEDQKDQVRIAALRRNLEERAGWTREDLKA
LRQRHRTVTDKQNSMANMMGMPQAQSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRMIQILSRKTKNNPVLVGDAGVGK
TALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAGTRFRGDFEERMNNIIKDIEEDGKVILFIDELHTIMGSGSGIDST
LDAANILKPALARGTLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSLADSMIILQGLKATYEKHHRVQITDEAVET
AVRMAHRYLTSRHLPDSAIDLLDEAAATVQNKSKHVKADESDLTPADKALMDGKWKQAAQLIAKEQEVPVYKDLVTESAI
LTTLSRLSGIPVQKLTQTDAKKYLNLEAELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAK
ALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQVLDD
GVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDIRFDQENMEKRIFEELKKAYRPEFINRIDEKVVFHSLDS
KHMQEIVKIMVKPLIASLAEKGIDLKLQASALKLLASHGYNPEMGARPLRRTLQTEVEDKLAELLLKGELVAGKTLKIGV
KAGQLKFDIA

Nucleotide

• Length: 2433 bp

>NTDB_id=812249 P8P68_RS07380 WP_278275838.1 1510077..1512509(+) (clpC) [Streptococcus sp. D7B5]
ATGAACTATTCAAAAGCATTGAATGAATGTATCGAAAGTGCCTACATGGTTGCGAGCCATTTTGGAGCCCATTATCTAGA
GTCTTGGCATTTATTGATTGCCATGTCCAATCACAGTTACAGTGTGGCAGGTGCGACTCTAAATGATTATCCATACGAGA
TGGACCGTTTAGAAGAGGTTGCGTTGGAACTGACTGAAACGGATTATAGCCAAGACGAAACCTTTACAGAATTACCCTTT
TCCCATCGTTTGGAGGTTCTCTTTGCAGAAGCAGAGTATGTGGCCTCAGTGGTCCATGCAAAGGTACTAGGGACAGAGCA
TGTCCTCTATGCGATTTTGCATGATGGCAATGCCTTGGCAACTCGCATCTTGGAGAGAGCGGGCTTTTCTTATGAAGACC
AAAAAGATCAGGTCAGAATTGCCGCTCTTCGTCGCAATCTAGAAGAGCGTGCAGGATGGACAAGAGAAGATCTCAAGGCT
TTGCGTCAACGCCATCGCACAGTAACTGACAAGCAAAATTCCATGGCTAATATGATGGGCATGCCTCAAGCTCAAAGTGG
TGGTCTAGAGGATTACACGCATGACCTGACGGAGCAAGCGCGCTCTGGCAAGTTAGAACCAGTTATCGGTCGTGACAAGG
AAATCTCGCGTATGATTCAGATTTTGAGTCGGAAGACCAAGAACAATCCTGTCTTGGTTGGAGATGCGGGTGTCGGGAAA
ACAGCTTTAGCACTTGGGCTTGCCCAGCGTATTGCTAGTGGGGACGTACCAGCTGAAATGGCAAAGATGCGTGTTCTAGA
GCTTGATTTGATGAATGTCGTTGCGGGAACACGTTTCCGTGGGGATTTTGAAGAGCGCATGAACAATATCATCAAGGACA
TCGAGGAAGATGGCAAAGTAATCCTCTTTATCGATGAACTTCACACCATCATGGGTTCTGGTAGCGGTATTGATTCGACT
CTGGATGCGGCCAATATCTTGAAGCCAGCCTTGGCTCGTGGAACTTTGAGAACGGTTGGTGCCACCACTCAGGAAGAATA
CCAGAAACACATCGAAAAAGATGCTGCCCTTTCTCGTCGGTTTGCCAAAGTGACGATTGAAGAGCCAAGCTTAGCTGACA
GCATGATCATTTTGCAAGGTTTGAAAGCGACCTATGAGAAACACCATCGTGTGCAAATCACAGATGAAGCTGTCGAAACG
GCTGTTAGGATGGCACATCGTTACTTGACCAGTCGTCACTTGCCAGACTCTGCTATCGACCTCTTGGATGAGGCGGCAGC
AACAGTGCAAAACAAATCCAAGCATGTGAAAGCAGACGAATCCGACTTGACTCCAGCTGACAAGGCCTTGATGGATGGCA
AGTGGAAACAAGCTGCCCAGTTAATCGCAAAAGAGCAGGAAGTCCCTGTCTATAAAGACTTGGTTACAGAATCCGCTATT
TTGACCACCTTGAGTCGCTTGTCAGGGATTCCAGTCCAAAAACTGACTCAGACTGATGCGAAGAAATACCTGAATCTGGA
AGCGGAACTGCACAAACGTGTCATCGGCCAAGATCAAGCTGTTTCAAGCATTAGTCGTGCCATTCGTCGCAATCAGTCAG
GTATTCGTAGTCACAAGCGTCCGATTGGTTCCTTTATGTTCCTAGGGCCGACAGGAGTCGGTAAGACCGAATTGGCAAAG
GCTCTGGCAGAAGTCCTCTTTGATGACGAATCAGCCCTTATCCGCTTTGATATGAGTGAGTATATGGAGAAATTTGCGGC
TAGCCGTCTCAATGGAGCACCTCCTGGCTATGTGGGCTACGAGGAAGGTGGGGAGTTGACCGAGAAGGTTCGCAACAAAC
CTTACTCAGTGCTTCTCTTTGACGAGGTAGAAAAGGCCCATCCAGACATCTTTAATGTCCTCTTGCAGGTTTTGGACGAC
GGCGTCTTGACAGATAGCAAGGGGCGCAAGGTTGATTTTTCAAATACCATTATCATCATGACGTCAAACCTTGGTGCGAC
GGCTCTTCGTGATGACAAGACGGTCGGCTTTGGGGCCAAGGATATTCGTTTTGACCAGGAAAATATGGAAAAACGAATCT
TTGAAGAGTTGAAAAAAGCTTATCGACCAGAGTTTATCAACCGTATTGATGAAAAGGTGGTCTTCCATAGCTTAGATAGC
AAGCACATGCAAGAAATTGTCAAGATTATGGTCAAACCATTGATTGCTAGCCTGGCAGAGAAAGGTATCGACTTGAAACT
GCAAGCTTCGGCACTGAAGTTGCTAGCTAGTCACGGTTACAATCCAGAAATGGGAGCTCGCCCACTTCGCAGAACCCTGC
AAACAGAAGTGGAAGACAAGTTGGCAGAACTTCTTCTCAAGGGAGAATTGGTGGCAGGTAAGACACTTAAGATTGGTGTC
AAAGCAGGCCAGTTAAAATTTGATATTGCTTAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (540-711)

• AAA lid domain (AAA_lid_9) (371-446)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (718-797)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (103-133)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (14-49)

• ATPase family associated with various cellular activities (AAA) (AAA) (231-362)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus pneumoniae D39	96.173	100	0.962
clpC	Streptococcus pneumoniae TIGR4	96.173	100	0.962
clpC	Streptococcus pneumoniae Rx1	96.173	100	0.962
clpC	Streptococcus mutans UA159	67.405	100	0.677
clpC	Streptococcus thermophilus LMD-9	66.953	100	0.673
clpC	Streptococcus thermophilus LMG 18311	66.83	100	0.672
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	49.396	100	0.505
clpC	Bacillus subtilis subsp. subtilis str. 168	44.951	100	0.451
clpE	Streptococcus mutans UA159	48.548	76.543	0.372