Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   P8632_RS04365 Genome accession   NZ_CP121263
Coordinates   869464..870180 (-) Length   238 a.a.
NCBI ID   WP_002455088.1    Uniprot ID   -
Organism   Staphylococcus hominis strain FSEL1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 864464..875180
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P8632_RS04345 (P8632_04335) - 865132..865356 (+) 225 WP_002448268.1 sulfurtransferase TusA family protein -
  P8632_RS04350 (P8632_04340) - 865467..866711 (+) 1245 WP_002448259.1 ammonium transporter -
  P8632_RS12380 - 866817..866884 (+) 68 Protein_850 LacI family DNA-binding transcriptional regulator -
  P8632_RS04355 (P8632_04345) - 866966..868453 (+) 1488 WP_002455086.1 sucrose-6-phosphate hydrolase -
  P8632_RS04360 (P8632_04350) - 868454..869425 (+) 972 WP_064207046.1 carbohydrate kinase family protein -
  P8632_RS04365 (P8632_04355) agrA 869464..870180 (-) 717 WP_002455088.1 quorum-sensing response regulator AgrA Regulator
  P8632_RS04370 (P8632_04360) agrC 870193..871482 (-) 1290 WP_002488053.1 quorum-sensing sensor histidine kinase AgrC -
  P8632_RS04375 (P8632_04365) agrD 871504..871644 (-) 141 WP_002488089.1 cyclic lactone autoinducer peptide AgrD -
  P8632_RS04380 (P8632_04370) - 871647..872213 (-) 567 WP_049437391.1 accessory gene regulator AgrB -
  P8632_RS04385 (P8632_04375) - 872913..873698 (-) 786 WP_002488076.1 carbon-nitrogen family hydrolase -
  P8632_RS04390 (P8632_04380) - 873829..874452 (-) 624 WP_326515178.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27858.75 Da        Isoelectric Point: 5.2104

>NTDB_id=811451 P8632_RS04365 WP_002455088.1 869464..870180(-) (agrA) [Staphylococcus hominis strain FSEL1]
MKIFICEDDVKQRENMVSIINNYIMIEEKPMEIALATDDPYEIIEQSKEMNDVGCYFLDIQLEADINGIKLGSEIRKYDP
IGNIIFVTSHSELTYLTFVYKVSAMDFIFKDDPNQLKTRIIDCIETAHTRLKLLSKESNVETIELKRGSNSIYVQYDDVM
FFESSTKSHRLIAHLDNRQIEFYGNLKELAQLDDRFFRCHNSFVVNRHNIDSVDSKERIVTFRNGEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=811451 P8632_RS04365 WP_002455088.1 869464..870180(-) (agrA) [Staphylococcus hominis strain FSEL1]
ATGAAAATATTCATTTGTGAAGACGATGTGAAACAACGTGAAAATATGGTTTCAATTATTAACAACTATATAATGATTGA
AGAAAAACCGATGGAAATAGCGTTAGCGACAGATGATCCTTATGAAATTATTGAACAGTCAAAAGAAATGAATGATGTTG
GATGTTATTTTTTAGATATACAATTGGAAGCTGATATTAACGGTATTAAACTTGGAAGTGAAATTCGAAAGTATGATCCT
ATTGGGAATATCATCTTTGTTACAAGTCATAGTGAACTCACTTACCTAACATTTGTCTATAAGGTATCTGCAATGGATTT
TATTTTTAAAGATGATCCTAATCAACTGAAAACGCGAATAATAGATTGCATTGAAACTGCTCATACACGTTTAAAATTAC
TTTCAAAAGAAAGCAATGTTGAAACAATTGAATTAAAACGTGGTAGCAATTCAATATATGTACAATATGATGATGTCATG
TTCTTTGAATCGTCTACAAAATCCCATCGTTTAATTGCACATCTTGATAACCGTCAGATTGAATTCTACGGAAATCTTAA
AGAATTAGCACAACTCGATGATCGTTTTTTCAGATGTCACAATAGTTTTGTTGTAAATCGCCATAATATCGATTCAGTCG
ATTCTAAAGAACGAATTGTAACTTTCAGAAATGGTGAGCATTGCTATGCCTCTGTACGTAATGTTAAAAAGATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

87.395

100

0.874