Detailed information NTG0081136

Bioinformatically predicted

Overview

• Name: uvrA
• Type: Machinery gene
• Locus tag: OPA53_RS23460
• Genome accession: NZ_AP026794
• Coordinates: 4770313..4773135 (+)
• Length: 940 a.a.
• NCBI ID: WP_000357755.1
• Uniprot ID: -
• Organism: Escherichia coli strain IPCEC48
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 4765313..4778135

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OPA53_RS23445 (IPCEC48_45170)	-	4766534..4768132 (-)	1599	WP_001050717.1	tyrosine-type recombinase/integrase	-
OPA53_RS23450	-	4768129..4769304 (-)	1176	WP_044067894.1	tyrosine-type recombinase/integrase	-
OPA53_RS23455 (IPCEC48_45190)	ssb1	4769522..4770058 (-)	537	WP_000168305.1	single-stranded DNA-binding protein SSB1	-
OPA53_RS23460 (IPCEC48_45200)	uvrA	4770313..4773135 (+)	2823	WP_000357755.1	excinuclease ABC subunit UvrA	Machinery gene
OPA53_RS23465 (IPCEC48_45210)	yjbR	4773170..4773526 (-)	357	WP_000153726.1	MmcQ/YjbR family DNA-binding protein	-
OPA53_RS23470 (IPCEC48_45220)	yjbQ	4773530..4773946 (-)	417	WP_000270369.1	secondary thiamine-phosphate synthase enzyme YjbQ	-
OPA53_RS23475 (IPCEC48_45230)	aphA	4774057..4774770 (-)	714	WP_001226933.1	acid phosphatase AphA	-
OPA53_RS23480 (IPCEC48_45240)	-	4775047..4776867 (+)	1821	WP_000704416.1	ATP-binding protein	-

Sequence

Protein

• Length: 940 a.a.
• Molecular weight: 103869.51 Da
• Isoelectric Point: 6.6065

>NTDB_id=81136 OPA53_RS23460 WP_000357755.1 4770313..4773135(+) (uvrA) [Escherichia coli strain IPCEC48]
MDKIEVRGARTHNLKNINLVIPRDKLIVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLS
PAISIEQKSTSHNPRSTVGTITEIHDYLRLLYARVGEPRCPDHDVPLAAQTVSQMVDNVLSQPDGKRLMLLAPIIKERKG
EHTKTLENLASQGYIRARIDGEVCDLSDPPKLELQKKHTIEVVVDRFKVRDDLTQRLAESFETALELSGGTAVVADMDDP
KAEELLFSANFACPICGYSMRELEPRLFSFNNPAGACPTCDGLGVQQYFDPDRVIQNPELSLAGGAIRGWDRRNFYYFQM
LKSLADHYKFDVEAPWGSLSANVHKVVLYGSGKENIEFKYMNDRGDTSIRRHPFEGVLHNMERRYKETESSAVREELAKF
ISNRPCASCEGTRLRREARHVYVENTPLPAISDMSIGHAMEFFNNLKLAGQRAKIAEKILKEIGDRLKFLVNVGLNYLTL
SRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLGTLIHLRDLGNTVIVVEHDEDAIRAADHVIDI
GPGAGVHGGEVVAEGPLEAIMAVPESLTGQYMSGKRKIEVPKKRVPANPEKVLKLTGARGNNLKDVTLTLPVGLFTCITG
VSGSGKSTLINDTLFPIAQRQLNGATIAEPAPYRDIQGLEHFDKVIDIDQSPIGRTPRSNPATYTGVFTPVRELFAGVPE
SRARGYTPGRFSFNVRGGRCEACQGDGVIKVEMHFLPDIYVPCDQCKGKRYNRETLEIKYKGKTIHEVLDMTIEEAREFF
DAVPALARKLQTLMDVGLTYIRLGQSATTLSGGEAQRVKLARELSKRGTGQTLYILDEPTTGLHFADIQQLLDVLHKLRD
QGNTIVVIEHNLDVIKTADWIVDLGPEGGSGGGEILVSGTPETVAECEASHTARFLKPML

Nucleotide

• Length: 2823 bp

>NTDB_id=81136 OPA53_RS23460 WP_000357755.1 4770313..4773135(+) (uvrA) [Escherichia coli strain IPCEC48]
ATGGATAAGATCGAAGTTCGGGGCGCCCGCACCCATAATCTCAAAAACATCAACCTCGTTATCCCCCGCGACAAGCTCAT
TGTCGTGACCGGGCTTTCGGGTTCTGGCAAATCCTCGCTCGCTTTCGACACCTTATATGCCGAAGGGCAGCGCCGTTACG
TTGAATCCCTTTCCGCCTACGCGCGGCAGTTTCTGTCACTGATGGAGAAGCCGGACGTCGACCATATTGAGGGGCTTTCT
CCTGCCATCTCAATTGAGCAGAAATCGACGTCTCATAACCCGCGCTCTACGGTGGGGACAATCACCGAAATCCACGACTA
TTTGCGTCTGCTGTACGCTCGCGTTGGTGAGCCGCGCTGCCCGGACCACGATGTACCGCTGGCGGCGCAAACCGTCAGTC
AGATGGTGGATAACGTGTTGTCCCAGCCGGACGGCAAGCGTCTGATGCTGCTCGCGCCAATCATTAAAGAGCGCAAAGGC
GAACACACCAAAACGCTGGAGAACCTGGCAAGCCAGGGTTACATCCGTGCTCGTATTGATGGCGAAGTCTGCGATCTTTC
CGATCCGCCGAAACTGGAACTGCAAAAGAAACATACCATTGAAGTGGTGGTTGATCGCTTCAAAGTGCGTGACGATCTTA
CCCAACGTCTTGCCGAGTCGTTTGAAACCGCGCTGGAGCTTTCCGGTGGTACCGCGGTAGTGGCGGATATGGACGACCCG
AAAGCGGAAGAGCTGCTGTTCTCCGCCAACTTTGCCTGCCCGATTTGCGGTTACAGTATGCGCGAGCTGGAACCTCGCCT
GTTTTCATTTAACAACCCGGCGGGAGCCTGCCCGACCTGTGACGGACTTGGCGTACAGCAATATTTCGATCCTGACCGCG
TGATCCAGAATCCGGAATTATCGCTGGCTGGCGGTGCGATCCGTGGCTGGGATCGCCGCAACTTCTATTATTTCCAGATG
CTGAAATCGCTGGCAGATCACTATAAGTTCGACGTCGAAGCGCCGTGGGGCAGCCTGAGCGCGAACGTGCATAAAGTGGT
GTTGTACGGTTCTGGCAAAGAAAATATTGAATTCAAATACATGAACGATCGTGGCGATACCTCCATTCGTCGTCATCCGT
TCGAAGGCGTGCTGCACAATATGGAGCGCCGTTATAAAGAGACGGAATCCAGCGCGGTACGTGAAGAATTAGCCAAGTTT
ATCAGCAATCGTCCGTGCGCCAGCTGCGAAGGAACCCGTCTGCGTCGGGAAGCACGCCACGTGTATGTCGAGAATACGCC
GCTGCCCGCCATCTCCGACATGAGCATCGGTCATGCGATGGAATTCTTCAACAATCTCAAACTCGCAGGTCAGCGGGCGA
AGATTGCAGAAAAAATCCTTAAAGAGATCGGCGATCGTCTGAAATTCCTCGTTAACGTCGGCCTGAATTACCTGACACTT
TCCCGCTCAGCAGAGACACTTTCCGGCGGTGAAGCCCAGCGTATTCGTCTGGCGAGCCAGATTGGTGCAGGCCTGGTTGG
CGTGATGTACGTGCTGGATGAGCCGTCTATCGGCCTGCACCAGCGCGATAACGAGCGCCTGCTGGGTACGCTTATCCATC
TGCGCGATCTCGGTAATACCGTGATTGTGGTGGAGCACGACGAAGACGCGATTCGCGCCGCTGATCATGTGATCGATATC
GGTCCGGGTGCGGGTGTTCACGGCGGTGAAGTCGTCGCGGAAGGTCCGCTGGAAGCAATAATGGCGGTGCCTGAGTCGTT
GACCGGGCAGTACATGAGCGGTAAACGCAAGATTGAGGTGCCGAAGAAACGCGTTCCGGCAAATCCGGAAAAAGTGCTGA
AACTGACGGGCGCACGCGGCAACAACCTGAAAGACGTGACGCTGACGCTGCCGGTGGGTCTGTTTACCTGCATTACCGGA
GTTTCAGGTTCCGGTAAATCAACGCTGATTAACGACACACTGTTCCCAATTGCCCAACGCCAGTTGAATGGTGCGACCAT
CGCCGAACCAGCACCGTATCGCGATATTCAGGGGCTGGAGCATTTCGATAAAGTGATCGATATCGACCAAAGCCCAATTG
GTCGTACTCCGCGTTCTAACCCGGCGACCTATACCGGCGTGTTTACGCCTGTGCGCGAACTGTTTGCGGGCGTACCGGAA
TCCCGTGCGCGTGGTTATACGCCAGGACGTTTCAGCTTTAACGTTCGCGGCGGACGCTGCGAAGCCTGTCAGGGCGACGG
CGTGATCAAAGTGGAGATGCACTTCCTGCCGGACATTTACGTACCGTGCGACCAGTGCAAAGGCAAACGCTATAACCGTG
AAACGCTGGAGATTAAGTACAAAGGCAAAACCATCCACGAAGTGCTGGATATGACCATCGAAGAGGCGCGTGAGTTCTTT
GATGCGGTGCCAGCTCTGGCACGTAAGCTGCAAACATTGATGGACGTTGGTCTGACGTATATTCGTCTGGGTCAGTCCGC
AACCACACTTTCTGGTGGTGAAGCCCAGCGCGTGAAGCTGGCGCGTGAGCTGTCAAAACGCGGCACCGGGCAGACGCTGT
ATATTCTCGACGAGCCGACCACCGGTCTGCACTTCGCCGATATTCAGCAACTGCTCGACGTACTGCATAAACTGCGCGAT
CAGGGCAATACCATTGTGGTAATTGAGCACAATCTCGACGTGATCAAAACCGCTGACTGGATTGTCGACCTGGGACCAGA
AGGCGGCAGTGGGGGCGGCGAAATCCTCGTCTCCGGTACGCCAGAAACCGTCGCAGAGTGCGAAGCTTCGCATACGGCGC
GCTTCCTCAAGCCGATGCTGTAA

Domains

Predicted by InterProScan.

• UvrA interaction domain (UvrA_inter) (130-237)

• UvrA DNA-binding domain (UvrA_DNA-bind) (290-399)

• ABC transporter (ABC_tran) (806-860)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrA	Streptococcus pneumoniae R6	57.37	100	0.576
uvrA	Streptococcus pneumoniae TIGR4	57.37	100	0.576
uvrA	Streptococcus pneumoniae D39	57.37	100	0.576