Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   P8191_RS06880 Genome accession   NZ_CP121250
Coordinates   1328504..1329457 (-) Length   317 a.a.
NCBI ID   WP_010921802.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain 1044     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1323504..1334457
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P8191_RS06850 (P8191_06850) - 1323723..1324040 (-) 318 WP_011285355.1 thioredoxin family protein -
  P8191_RS06855 (P8191_06855) - 1324037..1324321 (-) 285 WP_002992749.1 DUF4651 domain-containing protein -
  P8191_RS06860 (P8191_06860) pepA 1324786..1325853 (+) 1068 WP_029714177.1 glutamyl aminopeptidase -
  P8191_RS06865 (P8191_06865) proC 1325901..1326671 (+) 771 WP_010921805.1 pyrroline-5-carboxylate reductase -
  P8191_RS06870 (P8191_06870) - 1326754..1327062 (-) 309 WP_010921804.1 hypothetical protein -
  P8191_RS06875 (P8191_06875) - 1327249..1328445 (-) 1197 WP_010921803.1 acetate kinase -
  P8191_RS06880 (P8191_06880) comYH 1328504..1329457 (-) 954 WP_010921802.1 class I SAM-dependent methyltransferase Machinery gene
  P8191_RS06885 (P8191_06885) comGG 1329555..1329881 (-) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  P8191_RS06890 (P8191_06890) comYF 1329865..1330299 (-) 435 WP_010921800.1 competence type IV pilus minor pilin ComGF Machinery gene
  P8191_RS06895 (P8191_06895) comGE 1330292..1330576 (-) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE -
  P8191_RS06900 (P8191_06900) comGD 1330533..1330961 (-) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD -
  P8191_RS06905 (P8191_06905) comYC 1330936..1331262 (-) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  P8191_RS06910 (P8191_06910) comYB 1331264..1332298 (-) 1035 WP_011054115.1 competence type IV pilus assembly protein ComGB Machinery gene
  P8191_RS06915 (P8191_06915) comYA 1332234..1333172 (-) 939 WP_010921798.1 competence type IV pilus ATPase ComGA Machinery gene
  P8191_RS06920 (P8191_06920) - 1333265..1333630 (-) 366 WP_002986560.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 36015.10 Da        Isoelectric Point: 4.7205

>NTDB_id=811345 P8191_RS06880 WP_010921802.1 1328504..1329457(-) (comYH) [Streptococcus pyogenes strain 1044]
MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEGASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQT
EQLQANHQFTPDAIGFILLYLLEQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSLKYLKKDGFAIFLAPVNLLTSPQ
SQLLKQWLKDYAQVVTLITLPDSIFGHPSNAKSIIVLQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN

Nucleotide


Download         Length: 954 bp        

>NTDB_id=811345 P8191_RS06880 WP_010921802.1 1328504..1329457(-) (comYH) [Streptococcus pyogenes strain 1044]
ATGACTTTTGAAAAAATTGAAGAAGCTTATCAGCTGCTCTTAGAGAACTGTCAACTAATTGAAAATGATCTAAAAACACA
TATATACGATGCCATTGTTGAACAAAACTCCTTTTATTTAGGGGCTGAGGGAGCTAGTCCTCAAGTTGCTCAAAATAGTG
ATAAACTGAAAGCCTTGTGCCTGACAAAAGAAGAATGGCGTAAGGCCTACCAGTTTCTTTTTATTAAGGCAGCTCAGACT
GAGCAACTCCAAGCCAACCATCAGTTCACACCAGATGCTATTGGCTTCATTCTGCTGTATCTTTTGGAACAATTGAGTGA
TAAAGATAGCTTAGAGGTACTTGAGATTGGAAGTGGAACAGGGAACCTAGCCCAAACCCTTCTCAACAACACGAGCAAGA
GCCTTGATTATGTAGGGATTGAACTTGATGATCTCTTGATTGATCTGTCAGCCAGTATTGCTGAGATAATGGATTCTTCA
GCTCATTTTATTCAAGAAGATGCGGTAAGGCCTCAATTACTAAAAGAAAGTGACATTGTCATCAGTGACTTACCAGTTGG
TTATTATCCTAACGATGATATTGCCAAACGGTACAAGGTGGCTAGTTCAGATAAGCATACCTATGCCCATCATTTATTAA
TGGAACAGTCTTTAAAATACTTGAAAAAAGACGGTTTTGCGATTTTTCTGGCACCAGTCAATTTATTGACGAGCCCTCAG
AGCCAGTTGTTGAAACAGTGGTTAAAAGATTATGCTCAGGTGGTGACCTTGATTACGCTACCAGATTCTATTTTTGGTCA
TCCCTCAAATGCCAAGTCCATTATTGTCTTACAAAAACAAACAGACCACCCAATGGAAACCTTTGTCTATCCAATTCGGG
ATTTGAAGCTTGCAGAGAATATTCATGATTTTATGGAAAATTTCAAAAAATGGAAACTGAGTAATGTCAATTAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(68-288)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA159

65.823

99.685

0.656
  comYH Streptococcus mutans UA140

65.506

99.685

0.653