Detailed information
Bioinformatically predicted
Overview
| Name | pilK | Type | Machinery gene |
| Locus tag | HT073_RS02700 | Genome accession | NZ_AP023075 |
| Coordinates | 519308..519916 (+) | Length | 202 a.a. |
| NCBI ID | WP_003690900.1 | Uniprot ID | A0AB74EBN2 |
| Organism | Neisseria gonorrhoeae strain TUM16691 | ||
| Function | type IV pilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 515372..571445 | 519308..519916 | within | 0 |
Gene organization within MGE regions
Location: 515372..571445
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HT073_RS02680 (TUM16691C_05020) | dnaB | 515372..516778 (+) | 1407 | WP_003690896.1 | replicative DNA helicase | - |
| HT073_RS02685 (TUM16691C_05030) | pilH | 517086..517751 (+) | 666 | WP_003690897.1 | Tfp pilus assembly protein FimT/FimU | Machinery gene |
| HT073_RS02690 (TUM16691C_05040) | pilI | 517783..518391 (+) | 609 | WP_003690898.1 | type IV pilus modification protein PilV | Machinery gene |
| HT073_RS02695 (TUM16691C_05050) | pilJ | 518388..519329 (+) | 942 | WP_003690899.1 | PilW family protein | Machinery gene |
| HT073_RS02700 (TUM16691C_05060) | pilK | 519308..519916 (+) | 609 | WP_003690900.1 | PilX N-terminal domain-containing pilus assembly protein | Machinery gene |
| HT073_RS02705 (TUM16691C_05070) | pilL | 519918..520391 (+) | 474 | WP_025455782.1 | PilX family type IV pilin | Machinery gene |
| HT073_RS02710 (TUM16691C_05080) | - | 521003..521448 (-) | 446 | Protein_525 | AzlC family ABC transporter permease | - |
| HT073_RS02715 (TUM16691C_05090) | dut | 521614..522066 (+) | 453 | WP_003690909.1 | dUTP diphosphatase | - |
| HT073_RS02720 (TUM16691C_05100) | dapC | 522144..523331 (+) | 1188 | WP_003690911.1 | succinyldiaminopimelate transaminase | - |
| HT073_RS02725 (TUM16691C_05120) | yaaA | 523487..524266 (+) | 780 | WP_003690913.1 | peroxide stress protein YaaA | - |
| HT073_RS02740 (TUM16691C_05130) | - | 524797..525993 (+) | 1197 | WP_003704323.1 | integrase arm-type DNA-binding domain-containing protein | - |
| HT073_RS02745 (TUM16691C_05140) | - | 526349..526618 (-) | 270 | WP_003687928.1 | hypothetical protein | - |
| HT073_RS02750 (TUM16691C_05160) | - | 526813..527496 (-) | 684 | WP_003687929.1 | DUF2786 domain-containing protein | - |
| HT073_RS12150 | - | 527810..528043 (-) | 234 | Protein_532 | hypothetical protein | - |
| HT073_RS02760 (TUM16691C_05180) | - | 528154..528369 (-) | 216 | WP_003691538.1 | hypothetical protein | - |
| HT073_RS02765 (TUM16691C_05190) | - | 528421..528912 (-) | 492 | WP_003691537.1 | siphovirus Gp157 family protein | - |
| HT073_RS02770 (TUM16691C_05200) | - | 528909..529091 (-) | 183 | WP_003691535.1 | hypothetical protein | - |
| HT073_RS02775 (TUM16691C_05210) | - | 529231..529917 (-) | 687 | WP_003691532.1 | phage replication initiation protein, NGO0469 family | - |
| HT073_RS02780 (TUM16691C_05220) | - | 529986..530147 (-) | 162 | WP_003691530.1 | hypothetical protein | - |
| HT073_RS02785 (TUM16691C_05230) | - | 530144..530422 (-) | 279 | WP_003691529.1 | NGO1622 family putative holin | - |
| HT073_RS02790 (TUM16691C_05240) | - | 530575..530907 (-) | 333 | WP_003691528.1 | hypothetical protein | - |
| HT073_RS02795 (TUM16691C_05250) | - | 531048..531323 (-) | 276 | WP_003691527.1 | hypothetical protein | - |
| HT073_RS02800 (TUM16691C_05260) | - | 531320..531796 (-) | 477 | WP_003691526.1 | hypothetical protein | - |
| HT073_RS02805 (TUM16691C_05270) | - | 531829..532029 (-) | 201 | WP_003692842.1 | hypothetical protein | - |
| HT073_RS02810 (TUM16691C_05280) | - | 532227..532640 (-) | 414 | WP_003687963.1 | hypothetical protein | - |
| HT073_RS02815 (TUM16691C_05290) | - | 532637..533098 (-) | 462 | WP_003687965.1 | helix-turn-helix transcriptional regulator | - |
| HT073_RS02820 (TUM16691C_05300) | - | 533115..533552 (-) | 438 | WP_003687967.1 | hypothetical protein | - |
| HT073_RS02825 (TUM16691C_05310) | - | 533667..534383 (-) | 717 | WP_003687969.1 | LexA family transcriptional regulator | - |
| HT073_RS02830 (TUM16691C_05320) | - | 534452..534688 (+) | 237 | WP_003687971.1 | Cro/CI family transcriptional regulator | - |
| HT073_RS02835 (TUM16691C_05330) | - | 534768..534923 (+) | 156 | WP_047923772.1 | hypothetical protein | - |
| HT073_RS02840 (TUM16691C_05340) | - | 534900..535088 (-) | 189 | WP_050157615.1 | hypothetical protein | - |
| HT073_RS02845 (TUM16691C_05350) | - | 535262..535489 (+) | 228 | WP_003691442.1 | helix-turn-helix domain-containing protein | - |
| HT073_RS02850 (TUM16691C_05360) | - | 535486..536496 (+) | 1011 | WP_014580341.1 | helix-turn-helix domain-containing protein | - |
| HT073_RS02855 (TUM16691C_05370) | - | 536508..537287 (+) | 780 | WP_025455804.1 | ATP-binding protein | - |
| HT073_RS02860 (TUM16691C_05380) | - | 537300..537566 (+) | 267 | WP_172763933.1 | hypothetical protein | - |
| HT073_RS02865 (TUM16691C_05390) | - | 537605..538099 (+) | 495 | WP_003691434.1 | DUF3310 domain-containing protein | - |
| HT073_RS02870 (TUM16691C_05400) | - | 538276..538425 (+) | 150 | WP_003689110.1 | hypothetical protein | - |
| HT073_RS11665 (TUM16691C_05410) | - | 538454..538735 (+) | 282 | WP_003689109.1 | hypothetical protein | - |
| HT073_RS02875 (TUM16691C_05420) | - | 538726..539106 (+) | 381 | WP_017147222.1 | RusA family crossover junction endodeoxyribonuclease | - |
| HT073_RS12015 | - | 539123..539251 (-) | 129 | WP_012503747.1 | hypothetical protein | - |
| HT073_RS02880 (TUM16691C_05430) | - | 539373..539780 (+) | 408 | WP_003691430.1 | hypothetical protein | - |
| HT073_RS02885 (TUM16691C_05440) | - | 539871..541031 (+) | 1161 | WP_003691428.1 | type I restriction endonuclease | - |
| HT073_RS02890 (TUM16691C_05450) | - | 541315..542184 (+) | 870 | WP_106158880.1 | Bro-N domain-containing protein | - |
| HT073_RS02895 (TUM16691C_05460) | - | 542477..542926 (+) | 450 | WP_003695485.1 | hypothetical protein | - |
| HT073_RS02900 (TUM16691C_05470) | terL | 542988..544409 (+) | 1422 | WP_003697216.1 | phage terminase large subunit | - |
| HT073_RS02905 (TUM16691C_05480) | - | 544406..546553 (+) | 2148 | WP_003691423.1 | phage portal protein | - |
| HT073_RS02910 (TUM16691C_05490) | - | 546621..547778 (+) | 1158 | WP_010360058.1 | HK97 family phage prohead protease | - |
| HT073_RS02915 (TUM16691C_05500) | - | 547819..549318 (+) | 1500 | WP_003689084.1 | hypothetical protein | - |
| HT073_RS02920 (TUM16691C_05510) | - | 549325..549687 (+) | 363 | WP_003689082.1 | hypothetical protein | - |
| HT073_RS02925 (TUM16691C_05520) | - | 549690..550220 (+) | 531 | WP_003689080.1 | head-tail connector protein | - |
| HT073_RS02930 (TUM16691C_05530) | - | 550220..550702 (+) | 483 | WP_010360061.1 | HK97 gp10 family phage protein | - |
| HT073_RS02935 (TUM16691C_05540) | - | 550699..551127 (+) | 429 | WP_003689076.1 | hypothetical protein | - |
| HT073_RS02940 (TUM16691C_05550) | - | 551153..551926 (+) | 774 | WP_003692869.1 | hypothetical protein | - |
| HT073_RS02945 (TUM16691C_05560) | - | 551987..552316 (+) | 330 | WP_003689072.1 | hypothetical protein | - |
| HT073_RS02950 (TUM16691C_05570) | - | 552328..552594 (+) | 267 | WP_003689070.1 | hypothetical protein | - |
| HT073_RS02955 (TUM16691C_05580) | - | 552594..553193 (+) | 600 | WP_003691415.1 | DUF2460 domain-containing protein | - |
| HT073_RS02960 (TUM16691C_05590) | - | 553190..554044 (+) | 855 | WP_003698614.1 | DUF2163 domain-containing protein | - |
| HT073_RS02965 (TUM16691C_05600) | - | 554046..554477 (+) | 432 | WP_003689064.1 | NlpC/P60 family protein | - |
| HT073_RS02970 (TUM16691C_05610) | - | 554505..554783 (-) | 279 | WP_003689062.1 | XRE family transcriptional regulator | - |
| HT073_RS02975 (TUM16691C_05620) | - | 555023..559168 (+) | 4146 | WP_172763934.1 | phage tail protein | - |
| HT073_RS02980 (TUM16691C_05630) | - | 559280..559585 (+) | 306 | WP_003689058.1 | hypothetical protein | - |
| HT073_RS02985 (TUM16691C_05640) | - | 559656..560126 (+) | 471 | WP_003691410.1 | hypothetical protein | - |
| HT073_RS02990 (TUM16691C_05650) | - | 560127..560459 (+) | 333 | WP_003691408.1 | hypothetical protein | - |
| HT073_RS02995 (TUM16691C_05660) | - | 560827..561174 (-) | 348 | WP_003689051.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| HT073_RS03000 (TUM16691C_05670) | - | 561174..561410 (-) | 237 | WP_003689049.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | - |
| HT073_RS12020 | - | 561450..561575 (+) | 126 | WP_255294325.1 | hypothetical protein | - |
| HT073_RS03005 (TUM16691C_05680) | - | 561617..562156 (+) | 540 | WP_050163081.1 | TIGR02594 family protein | - |
| HT073_RS03010 (TUM16691C_05690) | - | 562157..562501 (+) | 345 | WP_003695464.1 | hypothetical protein | - |
| HT073_RS03015 (TUM16691C_05700) | - | 562485..562658 (+) | 174 | WP_017146757.1 | hypothetical protein | - |
| HT073_RS03020 | - | 562970..563119 (+) | 150 | WP_003691402.1 | hypothetical protein | - |
| HT073_RS03025 (TUM16691C_05710) | - | 563149..566196 (+) | 3048 | WP_172763935.1 | tape measure protein | - |
| HT073_RS03030 (TUM16691C_05720) | - | 566256..566735 (-) | 480 | WP_002241413.1 | DUF4760 domain-containing protein | - |
| HT073_RS03035 | - | 567077..568066 (-) | 990 | WP_003689040.1 | site-specific integrase | - |
| HT073_RS03040 (TUM16691C_05740) | - | 568326..568514 (-) | 189 | WP_003689039.1 | hypothetical protein | - |
| HT073_RS03045 (TUM16691C_05750) | purM | 568755..569789 (+) | 1035 | WP_003691398.1 | phosphoribosylformylglycinamidine cyclo-ligase | - |
| HT073_RS03055 (TUM16691C_05770) | - | 570792..571445 (+) | 654 | WP_017147274.1 | IS1595 family transposase | - |
Sequence
Protein
Download Length: 202 a.a. Molecular weight: 22023.05 Da Isoelectric Point: 7.5810
>NTDB_id=81125 HT073_RS02700 WP_003690900.1 519308..519916(+) (pilK) [Neisseria gonorrhoeae strain TUM16691]
MRKQNALTGIPTSEGQRGFALFIVLMVMIVVAFLVVTAAQSYNTEQRISANESDRKLALSLAEAALREGEFQVLDLEYTA
DSKVTFSENCENGLCTAVNVRTNDANEETFDNIVVKGKPTVEAVKRPCPAKSGKNSAGLCIDNKGMEYNKGVAGVSKMPR
YIIEYLGVKNGQNVYRVTAKAWGKNANTVVVLQSYVGNNDEQ
MRKQNALTGIPTSEGQRGFALFIVLMVMIVVAFLVVTAAQSYNTEQRISANESDRKLALSLAEAALREGEFQVLDLEYTA
DSKVTFSENCENGLCTAVNVRTNDANEETFDNIVVKGKPTVEAVKRPCPAKSGKNSAGLCIDNKGMEYNKGVAGVSKMPR
YIIEYLGVKNGQNVYRVTAKAWGKNANTVVVLQSYVGNNDEQ
Nucleotide
Download Length: 609 bp
>NTDB_id=81125 HT073_RS02700 WP_003690900.1 519308..519916(+) (pilK) [Neisseria gonorrhoeae strain TUM16691]
ATGCGCAAACAGAACGCTTTGACAGGAATCCCGACTTCTGAGGGACAGAGGGGGTTCGCACTGTTTATCGTGCTGATGGT
GATGATAGTCGTGGCCTTTTTGGTTGTAACTGCCGCCCAGTCCTACAATACCGAACAGAGGATCAGTGCCAACGAATCAG
ACAGGAAATTGGCTTTGTCTTTAGCCGAGGCGGCTTTGAGGGAAGGCGAATTTCAGGTTTTGGATTTGGAATATACTGCG
GATAGTAAGGTTACATTTAGCGAAAACTGTGAAAACGGCCTGTGTACCGCAGTGAATGTACGGACAAATGATGCTAATGA
AGAGACTTTTGACAATATCGTGGTGAAAGGCAAGCCTACCGTTGAGGCCGTGAAGCGTCCTTGCCCTGCAAAGTCTGGCA
AAAATTCTGCCGGTCTGTGCATTGACAATAAAGGGATGGAATATAATAAAGGCGTGGCAGGCGTCAGCAAAATGCCGCGC
TATATTATCGAATATTTAGGCGTGAAGAACGGACAAAATGTTTATCGGGTTACTGCCAAGGCTTGGGGTAAGAATGCCAA
TACCGTGGTCGTCCTTCAATCTTATGTAGGCAATAATGATGAGCAATAA
ATGCGCAAACAGAACGCTTTGACAGGAATCCCGACTTCTGAGGGACAGAGGGGGTTCGCACTGTTTATCGTGCTGATGGT
GATGATAGTCGTGGCCTTTTTGGTTGTAACTGCCGCCCAGTCCTACAATACCGAACAGAGGATCAGTGCCAACGAATCAG
ACAGGAAATTGGCTTTGTCTTTAGCCGAGGCGGCTTTGAGGGAAGGCGAATTTCAGGTTTTGGATTTGGAATATACTGCG
GATAGTAAGGTTACATTTAGCGAAAACTGTGAAAACGGCCTGTGTACCGCAGTGAATGTACGGACAAATGATGCTAATGA
AGAGACTTTTGACAATATCGTGGTGAAAGGCAAGCCTACCGTTGAGGCCGTGAAGCGTCCTTGCCCTGCAAAGTCTGGCA
AAAATTCTGCCGGTCTGTGCATTGACAATAAAGGGATGGAATATAATAAAGGCGTGGCAGGCGTCAGCAAAATGCCGCGC
TATATTATCGAATATTTAGGCGTGAAGAACGGACAAAATGTTTATCGGGTTACTGCCAAGGCTTGGGGTAAGAATGCCAA
TACCGTGGTCGTCCTTCAATCTTATGTAGGCAATAATGATGAGCAATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilK | Neisseria gonorrhoeae MS11 |
89.163 |
100 |
0.896 |